Data Sheet 2_Aurantii Fructus extract alleviates DSS-induced colitis in mice via regulating NF-κB and Nrf2/HO-1 signaling pathways and modulating intestinal microbiota.zip by JunBao Yu (22442218)

“…This study aimed to investigate the protective effects of Aurantii Fructus extract (AFE) on dextran sulfate sodium (DSS)-induced UC in mice and its impact on the gut microbiota.…”

Data Sheet 1_Allicin ameliorates acute myocardial infarction in rats by modulating calcium homeostasis in cardiomyocytes through the induction of hydrogen sulfide production.docx by Weiyu Liu (3879487)

“…</p>Results<p>The results indicate that allicin significantly enhanced cardiac function, raised H₂S levels in myocardial tissue and serum, reduced necrosis tissue size, decreased myocardial enzyme levels, and improved myocardial pathological changes. …”

Table 1_A dosimetric comparison of non-coplanar volumetric modulated arc therapy and non-coplanar fixed field intensity modulated radiation therapy in hippocampus-avoidance whole-b... by Huaqu Zeng (20601563)

“…VMAT significantly improved the V₃₀ of PTV-brain-SIB (p<0.001), decreased HI (p=0.003), and increased CI (p<0.001). …”

Table 1_WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer.docx by Jing Lv (128179)

“…MR analysis demonstrated that MSMB may be an important protective factor for prostate cancer. In q-PCR experiments conducted on tumor tissues and adjacent non-cancerous tissues from prostate cancer patients, it was found that: compared to the adjacent non-cancerous tissues, the expression level of ARHGEF38 in prostate cancer tumor tissues significantly increased, while the expression levels of SLC14A1, NEFH, MSMB, KRT23, and KRT15 significantly decreased. …”

Image 1_WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer.tif by Jing Lv (128179)

“…MR analysis demonstrated that MSMB may be an important protective factor for prostate cancer. In q-PCR experiments conducted on tumor tissues and adjacent non-cancerous tissues from prostate cancer patients, it was found that: compared to the adjacent non-cancerous tissues, the expression level of ARHGEF38 in prostate cancer tumor tissues significantly increased, while the expression levels of SLC14A1, NEFH, MSMB, KRT23, and KRT15 significantly decreased. …”

Data Sheet 1_Molecular insights into Atorvastatin’s role in delaying intervertebral disc degeneration.zip by Yupeng Li (507508)

“…Atorvastatin enhanced the antioxidant capacity of NPCs and decreased intracellular ROS accumulation. It promoted Nrf2 activation and upregulated the expression of downstream antioxidant factors, thereby exerting a protective effect against oxidative stress–induced injury. …”

Table 1_GLP1 receptor agonists and SGLT2 inhibitors for the prevention or delay of type 2 diabetes mellitus onset: a systematic review and meta-analysis.docx by Farah Ghobar (22480732)

“…Background<p>SGLT-2 inhibitors (SGLT-2i) and GLP-1 receptor agonists (GLP-1 RA) are two widely used classes of medications in the treatment of diabetes, each demonstrating significant efficacy and adoption. These medications have shown promising results in glycemic control and offer additional health benefits such as weight loss and cardiovascular protection. …”

Table 1_A global analysis of nasopharynx cancer burden attributable to occupational formaldehyde exposure.docx by Jian Li (41607)

“…From 1990 to 2021, global age-standardized mortality rates (ASMR) and age-standardized DALYs rates (ASDR) decreased, although significant increases were observed in the Caribbean and Central Asia. …”

Data Sheet 1_Prepandemic levels of cytokines and immunoglobulins and risk of SARS-CoV-2 infection and COVID-19 in the general population of Barcelona.docx by Miquel Porta (199379)

“…</p>Results<p>Higher concentrations in 2016–17 of IL-8 and TNF-α significantly decreased the risk of SARS-CoV-2 seropositivity in 2020–21, whereas higher concentrations of MIP-1α were a risk factor for seropositivity. …”

Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer” by Chanping You (9067448)

“…Inhibition of NHEJ with the DNA-PKcs inhibitor KU-57788 reversed the protective effect of CRY2, confirming AR modulates doxorubicin response via CRY2-driven NHEJ activation.…”

Rutin attenuates iron overload induced-ferroptosis in rats’ heart tissue by Haidy A. Abdullah (21339819)

“…After rutin treatment, our results revealed that TIBC, ferritin, transferrin, hepicidin, MDA&NO were significantly decreased, while GSH level and GPx&SOD activities were significantly increased. …”

Da-Yuan-Yin decoction suppresses NETs formation, inhibits the IL-23/JAK2/STAT3 signalling pathway, and modulates metabolic profiles and gut microbiota composition in damp-heat synd... by Yun Yang (417125)

“…Complete blood count (CBC), blood biochemistry, short-chain fatty acids (SCFAs), gut microbiota composition in the colon, and metabolites in the cecum were analyzed.</p> <p>DYY significantly reduced symptom scores and decreased CRP level, while also regulating parameters in CBC and biochemical profiles. …”

Data Sheet 1_Role of RGS17 in cisplatin-induced cochlear inflammation and ototoxicity via caspase-3 activation.zip by Raheem F. H. Al Aameri (14951800)

“…<p>Cisplatin is a chemotherapy drug used to treat different solid tumors, including ovarian, bladder, lung, and head and neck cancers. One of its significant side effects is ototoxicity, especially when high doses are required. …”

Data Sheet 1_Crop rotation complexity affects soil properties shaping antibiotic resistance gene types and resistance mechanisms.docx by Rong Hu (153724)

“…Furthermore, differential gene analysis identified four specific types of ARGs—glycopeptide, multidrug, fluoroquinolone, and macrolide-lincosamide-streptogramin B (MLSB)—and two resistance mechanisms—cellular protection and efflux pump. Notably, soil microbial biomass carbon, soil microbial biomass nitrogen, and soil organic carbon are significantly correlated with ARGs in complex crop rotation systems, whereas soil pH and C/N ratio show significant associations in BL. …”

Cholecalciferol alleviates testicular dysfunction in experimental hyperthyroidism via antioxidant, anti-inflammatory and antiapoptotic effects by Heba Rady Salem (21356361)

“…It significantly decreased the levels of serum inflammatory markers and malondialdehyde levels. …”

Source data.zip by Xiaoyan Pan (21158717)

“…In vivo, melatonin significantly increased MT1R (melatonin receptor 1A) expression in BPA-treated mouse testicular cells and the content of catalase, superoxide dismutase 2, and glutathione, while decreasing the level of malondialdehyde. …”

Mitigation of Senescence Burden in Doxorubicin-Induced Senescent Endothelial Cells by MitoQ Treatment Through Diminishing Mitochondrial ROS and DNA Damage. by Hossein Abdeahad (22177792)

“…DOXO increased mtROS, decreased mitochondrial mass, and induced senescence. …”

Table 3_Effects of silver nanoparticles on the physiology, stress, and mineral uptake of banana cultivars in vitro and greenhouse.xlsx by Natalia Mendoza (22038296)

“…Rooting experiments revealed similar trends with high AgNP concentrations resulting in a decreasing root number and size. Greenhouse experiments on Gros Michel bananas, evaluating AgNP uptake through foliar and drench applications at 0, 25, 50, and 100 mg L^-1, monitored over a month, showed no statistically significant differences in growth parameters between treated plants and controls. …”

Table 5_Effects of silver nanoparticles on the physiology, stress, and mineral uptake of banana cultivars in vitro and greenhouse.xlsx by Natalia Mendoza (22038296)

“…Rooting experiments revealed similar trends with high AgNP concentrations resulting in a decreasing root number and size. Greenhouse experiments on Gros Michel bananas, evaluating AgNP uptake through foliar and drench applications at 0, 25, 50, and 100 mg L^-1, monitored over a month, showed no statistically significant differences in growth parameters between treated plants and controls. …”

Table 2_Effects of silver nanoparticles on the physiology, stress, and mineral uptake of banana cultivars in vitro and greenhouse.xlsx by Natalia Mendoza (22038296)

“…Rooting experiments revealed similar trends with high AgNP concentrations resulting in a decreasing root number and size. Greenhouse experiments on Gros Michel bananas, evaluating AgNP uptake through foliar and drench applications at 0, 25, 50, and 100 mg L^-1, monitored over a month, showed no statistically significant differences in growth parameters between treated plants and controls. …”