Search alternatives:
significant protective » significant positive (Expand Search), significant potential (Expand Search), significant proteomic (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
protective decrease » progressive decrease (Expand Search)
significant protective » significant positive (Expand Search), significant potential (Expand Search), significant proteomic (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
protective decrease » progressive decrease (Expand Search)
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1221
DataSheet1_Synergistic combinations of Angelica sinensis for myocardial infarction treatment: network pharmacology and quadratic optimization approach.docx
Published 2024“…Further research revealed that Z-LIG/CGA treatment significantly increased IL-1R2 levels, significantly decreased IL-17RA levels, and inhibited the activation of p-STAT1, thereby alleviating cell apoptosis after MI. …”
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1222
Table 1_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx
Published 2025“…In MAFLD mice, TFA treatment significantly decreased body weight gain, hepatic lipid accumulation, and the serum levels of ALT, AST, TC, and TG. …”
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1223
Table 2_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx
Published 2025“…In MAFLD mice, TFA treatment significantly decreased body weight gain, hepatic lipid accumulation, and the serum levels of ALT, AST, TC, and TG. …”
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1224
Image 3_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif
Published 2025“…Auditory brainstem response (ABR) thresholds were significantly elevated, and distortion-product otoacoustic emissions (DPOAE) indicated outer hair cell dysfunction. …”
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1225
Image 5_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif
Published 2025“…Auditory brainstem response (ABR) thresholds were significantly elevated, and distortion-product otoacoustic emissions (DPOAE) indicated outer hair cell dysfunction. …”
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1226
Data Sheet 2_Preventive hyperbaric oxygen therapy improves acute graft-versus-host disease by activating the Nrf2/HO-1 pathway.docx
Published 2025“…ML385, an Nrf2 inhibitor, was used to validate the protective role of Nrf2 in the beneficial effect of HBOT on aGVHD. …”
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1227
Image 2_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif
Published 2025“…Auditory brainstem response (ABR) thresholds were significantly elevated, and distortion-product otoacoustic emissions (DPOAE) indicated outer hair cell dysfunction. …”
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1228
Table_1_RETRACTED: miR-335 Targets LRRK2 and Mitigates Inflammation in Parkinson’s Disease.DOCX
Published 2025“…LRRK2-Wt-induced proinflammatory gene expression was also significantly reduced by miR-335 overexpression. Finally, in SH-SY5Y neuroblastoma cells, miR-335 decreased the expression of pro-inflammatory genes triggered by α-synuclein. …”
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1229
Data Sheet 1_Preventive hyperbaric oxygen therapy improves acute graft-versus-host disease by activating the Nrf2/HO-1 pathway.pdf
Published 2025“…ML385, an Nrf2 inhibitor, was used to validate the protective role of Nrf2 in the beneficial effect of HBOT on aGVHD. …”
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1230
Image 1_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif
Published 2025“…Auditory brainstem response (ABR) thresholds were significantly elevated, and distortion-product otoacoustic emissions (DPOAE) indicated outer hair cell dysfunction. …”
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1231
Supplementary Material for: Bidirectional Impact of Varying Severity of Acute Kidney Injury on Calcium Oxalate Stone Formation
Published 2024“…Transcriptomic analysis revealed that genes associated with inflammation and cell adhesion pathways were significantly upregulated after severe AKI, while genes related to energy metabolism pathways were significantly upregulated after mild AKI. …”
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1232
Image 4_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif
Published 2025“…Auditory brainstem response (ABR) thresholds were significantly elevated, and distortion-product otoacoustic emissions (DPOAE) indicated outer hair cell dysfunction. …”
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1233
Data Sheet 1_Assessing ecological environmental quality and conservation effectiveness in the World’s largest urban green heart using the remote sensing ecological index (RSEI) and...
Published 2025“…The findings reveal that: (1) The RSEI demonstrated an average annual growth rate of 0.0038 years<sup>-1</sup> over 31 years, with significant increases during 1990–2013 (0.0045 years<sup>-1</sup>) and 2013–2020 (0.0089 years<sup>-1</sup>). (2) Comparing pre- and post-GH policy implementation periods (1990–2013 vs. 2013–2020), areas showing EEQ improvement increased from 77.15% to 89.69%, while areas with stable and decreased EEQ declined from 22.36% to 10.17%. (3) GH policy demonstrates substantial positive conservation effects, with both GH and the 3 km buffer zone exhibiting EEQ improvements. …”
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1234
Data source and description.
Published 2025“…<div><p>It is significant to explore the evolution pattern and driving mechanism of non-grain of cultivated land in the main grain-producing areas to promote the sustainable development of agriculture and guarantee national food security. …”
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1235
Analytical framework.
Published 2025“…<div><p>It is significant to explore the evolution pattern and driving mechanism of non-grain of cultivated land in the main grain-producing areas to promote the sustainable development of agriculture and guarantee national food security. …”
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1236
Table1_Interannual hydrological changes affect plant communities across different elevation zones in plateau lakeshores: insights from Lake Erhai.docx
Published 2024“…The results showed that (1) In drought years, the Shannon-Wiener index of plants significantly decreased across the three elevation ranges, and other plant diversity indices, biomass, and coverage also decreased to varying degrees; (2) except for soil pH, soil water (SW) and nutrient content decreased to varying degrees in the drought year; (3) SW was the primary factor influencing plant biomass, coverage, and diversity in the 1965.0-1965.3m and 1965.3-1965.6m ranges; nitrate nitrogen, C/N ratio, total phosphorus were the primary factors in the 1965.6-1966.4m ranges. …”
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1237
Data Sheet 1_Polydatin combined with hawthorn flavonoids alleviate high fat diet induced atherosclerosis by remodeling the gut microbiota and glycolipid metabolism.pdf
Published 2025“…</p>Results<p>Polydatin combined with hawthorn flavonoids administration significantly reduced lipid and inflammatory cytokine levels, meanwhile, the atherosclerotic lesions in a high-fat diet-induced ApoE<sup>−/−</sup> mice were significantly decreased. …”
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1238
Soluble average Klotho level as a prognostic marker for acute kidney injury outcomes: a 90-day follow-up study
Published 2025“…</p> <p>The sKlotho level decreased significantly with kidney injury and represented severity. …”
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1239
Table 1_Global burden of pneumoconiosis from 1990 to 2021: a comprehensive analysis of incidence, mortality, and socio-demographic inequalities in 204 countries and territories.doc...
Published 2025“…These occupational hazards are exacerbated by inadequate dust control measures, insufficient use of personal protective equipment (PPE), and underreporting in low-and middle-income countries (LMICs). …”
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1240
Table 1_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx
Published 2025“…</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …”