Search alternatives:
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant protein » significant proteomic (Expand Search), significant protective (Expand Search), significant promoting (Expand Search)
protein database » prospero database (Expand Search), protein data (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant protein » significant proteomic (Expand Search), significant protective (Expand Search), significant promoting (Expand Search)
protein database » prospero database (Expand Search), protein data (Expand Search)
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Presentation 1_Decreased brain-derived neurotrophic factor expression in chronic kidney disease: integrated clinical and experimental evidence.pptx
Published 2025“…However, the evidence and regulatory mechanisms underlying decreased BDNF levels in CKD remain inconclusive.</p>Methods<p>This study systematically evaluated circulating BDNF alterations in CKD patients through a meta-analysis of clinical studies involving 1,549 participants, complemented by experimental validation in unilateral ureteral obstruction (UUO) mice and single-cell transcriptomic database analysis to investigate tissue-specific BDNF protein expression and regulatory patterns.…”
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Data Sheet 1_Decreased brain-derived neurotrophic factor expression in chronic kidney disease: integrated clinical and experimental evidence.docx
Published 2025“…However, the evidence and regulatory mechanisms underlying decreased BDNF levels in CKD remain inconclusive.</p>Methods<p>This study systematically evaluated circulating BDNF alterations in CKD patients through a meta-analysis of clinical studies involving 1,549 participants, complemented by experimental validation in unilateral ureteral obstruction (UUO) mice and single-cell transcriptomic database analysis to investigate tissue-specific BDNF protein expression and regulatory patterns.…”
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Quantitative analysis.
Published 2024“…ELISA results revealed that the levels of key inflammatory cytokines (TNF-α, IL-1β, IL-17 and IL-23) were significantly elevated in the LPS-treated model group (<i>P</i><0.0001, <i>P</i><0.001), but these levels were significantly decreased after NMRAL1 siRNA transfection (<i>P</i><0.0001, <i>P</i><0.01, <i>P</i><0.05).…”
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GSVA results.
Published 2024“…Additionally, decreased PDHB mRNA and protein expression levels were observed in the cardiac tissue of septic mice compared to control mice.…”
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Differential expressed genes.
Published 2024“…Additionally, decreased PDHB mRNA and protein expression levels were observed in the cardiac tissue of septic mice compared to control mice.…”
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S1 Raw image -
Published 2024“…Additionally, decreased PDHB mRNA and protein expression levels were observed in the cardiac tissue of septic mice compared to control mice.…”
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Venn plot.
Published 2024“…Additionally, decreased PDHB mRNA and protein expression levels were observed in the cardiac tissue of septic mice compared to control mice.…”
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Key module genes.
Published 2024“…Additionally, decreased PDHB mRNA and protein expression levels were observed in the cardiac tissue of septic mice compared to control mice.…”
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Univariate and multivariate Cox analysis.
Published 2024“…Additionally, decreased PDHB mRNA and protein expression levels were observed in the cardiac tissue of septic mice compared to control mice.…”