يعرض 301 - 320 نتائج من 401 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant proteomic decrease ))~', وقت الاستعلام: 0.31s تنقيح النتائج
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    Table1_Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pat... حسب Boris Jakopovic (9265517)

    منشور في 2024
    "…</p>Methods<p>In this study, we performed both qualitative and quantitative proteomic analyses using tandem mass tags (TMT) on CT26 wild type (CT26. …"
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    ZIKV infection enriches the HLA Class I pathway in brain tumour cells. حسب Matt Sherwood (22530221)

    منشور في 2025
    "…Normalised enrichment score (NES) denotes the degree to which the enrichment increased (+) or decreased (-). GSEA analysis significance is defined by p ≤ 0.05 and FDR ≤ 0.25. …"
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    Reduced mitochondrial function and protein expression in 21-28wk-old R14<sup>Δ/+</sup> mice. حسب Brian Foo (19273132)

    منشور في 2024
    "…. * p < 0.05, ns = non-significant. E-H) Global protein expression assessed in 21 wk-old ♂ WT and R14<sup>Δ/+</sup> mice via bottom-up DIA-MS proteomics workflows (N = 4). …"
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    DataSheet1_Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic... حسب Boris Jakopovic (9265517)

    منشور في 2024
    "…</p>Methods<p>In this study, we performed both qualitative and quantitative proteomic analyses using tandem mass tags (TMT) on CT26 wild type (CT26. …"
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    Figure 2 from mTORC1-Driven Protein Translation Correlates with Clinical Benefit of Capivasertib within a Genetically Preselected Cohort of <i>PIK3CA</i>-Altered Tumors حسب Constance A. Sobsey (19373550)

    منشور في 2025
    "…Node size increases as the <i>P</i>-value decreases. <b>B,</b> Top 20 canonical pathways that are significantly differentially activated between clinical benefit (CB) and no clinical benefit (NCB) groups, based on assessment with Fisher’s exact test in Qiagen IPA. …"
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    Additional file 1 of MDM2-amplified esophageal adenocarcinomas exhibit an activated metabolic and immunosuppressive phenotype with multiple potential therapeutic targets حسب Karl Knipper (15016346)

    منشور في 2025
    "…Grey: not significantly different expressed, blue: significantly decreased expression in neoadjuvantly treated MDM2-amplified tumors, red: significantly increased expression in neoadjuvantly treated MDM2-amplified tumors. …"
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    Unraveling the immunosuppressive role of Elastase B produced by cystic fibrosis isolates of <i>Pseudomonas aeruginosa</i> in an organotypic 3D lung epithelial cell model حسب Merel Wauters (21333023)

    منشور في 2025
    "…Compared to the <i>lasB</i> mutant, the wild-type strain significantly decreased inflammation by degrading MCP-1, IL-1β, GM-CSF, and IL-8. …"
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    Downregulation of ATM1 affects iron-sulfur cluster proteins in <i>Toxoplasma</i> and iron levels in <i>Plasmodium</i>. حسب Deepti Shrivastava (17715780)

    منشور في 2024
    "…The number of significantly increased and decreased proteins is given and the NEET protein CDGSH1 is indicated. …"
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    Multi-omics revealed GOT1/ALDH3A1 pathway attenuated head and neck squamous cell carcinoma and increased cisplatin sensitivity through ROS induced by mitochondrial dysfunction حسب Zhihui Liu (95891)

    منشور في 2025
    "…Given that mitochondria are the primary source of reactive oxygen species (ROS), we assessed cellular ROS and mitochondrial superoxide levels by flow cytometry and found a significant increase. GOT1 knockdown increased the sensitivity of cells to cisplatin and decreased the volume of tumors in vivo. …"
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    Multiomics Identified the Nutritional Improvement in LAB-Fermented Goat Milk حسب Liyan Ge (13017372)

    منشور في 2025
    "…Using multiomics, we found that FGM has reduced microbial diversity, with increased <i>Streptococcus</i> and <i>Lactobacillus</i> and decreased <i>Klebsiella</i>. Metabolomics identified 364 metabolites (59 differential), and proteomics found 334 proteins (20 differential). …"
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    Down-Regulation of Annexin A Proteins in Human Mesangial Cells by TEGDMA and Bis-GMA Treatment Disrupts Proteins Involved in Cellular Function حسب Ayse Nur Dogan (21015836)

    منشور في 2025
    "…Transient knockdown of annexin A2 protein expression using annexin A2 siRNA resulted in a significant decrease in alpha smooth muscle actin and non-muscle myosin protein expression in human mesangial cells when compared to cells transfected with non-targeting control siRNA. …"
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    TgHCF101 is involved in Fe-S cluster biogenesis of the CIA pathway. حسب Eléa A. Renaud (18192764)

    منشور في 2025
    "…Significant hits corresponding to predicted Fe-S cluster proteins are highlighted in red on the graph. …"