Search alternatives:
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
reduction decrease » reduction decreased (Expand Search), reduction reuse (Expand Search), production increases (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
reduction decrease » reduction decreased (Expand Search), reduction reuse (Expand Search), production increases (Expand Search)
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3921
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Synthesis and Biological Evaluation of MEK/mTOR Multifunctional Inhibitors as Novel Anticancer Agents
Published 2025“…Additionally, compound LP-65 demonstrated significant modulation of MEK and mTOR signaling activity in human glioma cells (D54) and human melanoma cells (A375), with a corresponding decrease in cellular proliferation and migration. …”
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3931
Study Data.
Published 2025“…It has also been hypothesized that the bradycardia and rare instances of cardiac arrest occurring after the use of sugammadex may be due to a transient decrease in circulating corticosteroids, causing a temporary ‘mini Addisonian crisis.’ …”
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3932
Study outcomes.
Published 2025“…It has also been hypothesized that the bradycardia and rare instances of cardiac arrest occurring after the use of sugammadex may be due to a transient decrease in circulating corticosteroids, causing a temporary ‘mini Addisonian crisis.’ …”
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3933
Patient characteristics.
Published 2025“…It has also been hypothesized that the bradycardia and rare instances of cardiac arrest occurring after the use of sugammadex may be due to a transient decrease in circulating corticosteroids, causing a temporary ‘mini Addisonian crisis.’ …”
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Vitamin D3, but not the Cisplatin, could moderately reduce STZ-induced hyperglycemia in mice (a) Schematic representation of experimental protocol followed in the study: After accl...
Published 2025“…(c) Vitamin D3 and the positive control Cisplatin differently modulated FBG in hyperglycaemic mice: Intraperitoneal administration of vitamin D3 very minimally decreased FBG compared to vehicle control at the end of the study. …”
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3936
Changes in the active H3K27ac and repressive H3K27me3 histone marks among Vasa2+/Piwi1+ and all cells in fed, starved, and refed juvenile polyps.
Published 2025“…Between fed, T<sub>5ds</sub> and T<sub>20ds</sub> timepoints, MFI levels of H3K27ac progressively and significantly decreased while levels H3K27me3 (M) did not change significantly (N). …”
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The TOR inhibitors Rapamycin and AZD-8055 strongly reduce RPS6 phosphorylation and cell proliferation in Vasa2+/Piwi1+ cells.
Published 2025“…<i>n</i> = 2–4 biological replicates per condition, with 15 individuals per replicate. Significance levels for Student <i>t</i> test are indicated for adjusted <i>p</i> values: *<i>p</i> < 0.05, ***<i>p</i> < 0.001, ***<i>p</i> < 0.0001. d: day(s), n.s.: non-significant. …”
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Repetitive stress induces a reduction in sound-evoked activity that develops as the stressor becomes chronic.
Published 2025“…On the initial day of stress, there was no significant reduction in activity, but as the stressor became chronic, the reduction increased (mean ± SE, 1-way ANOVA, condition S1 F = 1.9, <i>p</i> = 0.16, S5 F = 27.5, <i>p</i> = 1.7 × 10<sup>−07</sup>, nested ANOVA (mouse nested within session) condition S1 F = 2.8, <i>p</i> = 0.09, S5 F = 32.7, <i>p</i> = 1.3 × 10<sup>−08</sup>). …”