Supplementary file 1_Hydroxysafflor yellow A alleviates oxidative stress and inflammatory damage in the livers of mice with nonalcoholic fatty liver disease and modulates gut micro... by Liang Wu (131111)

“…Gut microbiota analysis revealed a significant increase in the abundance of Turicibacter, while a reduction of Ruminococcus. …”

Data Sheet 1_Efficacy and safety of PCSK9 inhibitors, potent statins, and their combinations for reducing low-density lipoprotein cholesterol in hyperlipidemia patients: a systemat... by Yuhua Jiang (10300159)

“…Meanwhile, compared with placebo, evolocumab (MD −1.89, 95% CI −2.27 to −1.50), alirocumab (MD −1.83, 95% CI −2.09 to −1.57), rosuvastatin (MD −1.93, 95% CI −2.30 to −1.56), inclisiran (MD −1.68, 95% CI −2.10 to −1.27), and atorvastatin (MD −1.68, 95% CI −2.04 to −1.31) could also play a role in the treatment of LDL-C reduction. Moreover, the incidence of adverse events (AEs) was similar to that observed in the control group, which included both placebo and potent statin groups, with no significant differences identified in our study (P > 0.05).…”

Data Sheet 2_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.pdf by Sofie Vandendriessche (638514)

“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”

Table 1_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.xlsx by Sofie Vandendriessche (638514)

“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”

Table 2_Mortality and trends of pulmonary arterial hypertension, 1990–2021: a population-based study.docx by Linhong Jiang (5004347)

“…Adequate diagnosis and targeted treatment of PAH are urgently needed to achieve a reduction in mortality.</p>…”

Image 1_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.tif by Chandrasekar Karthika (21255878)

“…In vitro investigations demonstrated that the phage cocktail significantly decreased both planktonic and sessile cells. …”

<b>Identification and Validation of LOXL2 as a Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma through Multi-Omics and Functional Analysis</b> by Ge Qiao (21802511)

“…Immune infiltration analyses revealed a correlation between elevated LOXL2 levels and an immunosuppressive cancer microenvironment, characterized by an increase in regulatory T cells and M2 macrophages, along with a reduction in cytotoxic CD8+ T cells. LOXL2 knockdown led to decreased tumor cell proliferation, enhanced apoptosis, and cell cycle arrest. …”

Video 3_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.mp4 by Sofie Vandendriessche (638514)

“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”

Image 5_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.tif by Chandrasekar Karthika (21255878)

“…In vitro investigations demonstrated that the phage cocktail significantly decreased both planktonic and sessile cells. …”

DataSheet1_Accumulation of coumaric acid is a key factor in tobacco continuous cropping obstacles.docx by Meng Jia (696568)

“…Simultaneously, the abundance of bacteria related to nutrient utilization (e.g., Flavisolibacter, Methylobacterium) and fungi related to disease resistance (e.g., Fusicolla, Clonostachys) gradually decreased, along with a reduction in soil catalase, urease, invertase, and acid phosphatase activities. …”

QbD-based co-loading of paclitaxel and imatinib mesylate by protamine-coated PLGA nanoparticles effective on breast cancer cells by Neha Laxane (19851759)

“…</p> <p>Protamine coating was clearly visible on images using transmission electron microscopy analysis.</p> <p>Significant reduction in IC₅₀ values showing increased cytotoxicity was observed.…”

Table 2_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.doc by Chandrasekar Karthika (21255878)

“…In vitro investigations demonstrated that the phage cocktail significantly decreased both planktonic and sessile cells. …”

Table 1_Mortality and trends of pulmonary arterial hypertension, 1990–2021: a population-based study.docx by Linhong Jiang (5004347)

“…Adequate diagnosis and targeted treatment of PAH are urgently needed to achieve a reduction in mortality.</p>…”

Table 1_Carnosine as a protective metabolic mediator in inflammatory lung injury by inhibiting macrophage infiltration and M1-like polarization.docx by Lianjie Ruan (22660265)

“…Multiplex immunofluorescence further demonstrated a significant reduction of macrophage accumulation in the peribronchial regions of the lung following carnosine administration. …”

Image 3_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.tif by Chandrasekar Karthika (21255878)

“…In vitro investigations demonstrated that the phage cocktail significantly decreased both planktonic and sessile cells. …”

Image 6_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.tif by Chandrasekar Karthika (21255878)

“…In vitro investigations demonstrated that the phage cocktail significantly decreased both planktonic and sessile cells. …”

Pharmacological evaluation of <i>Kigelia pinnata</i> root bark ethanolic extract in DOCA salt-induced hypertension in experimental rats by Ravindra Kumar (524606)

“…Importantly, supplementation with ethanolic extract from the root bark of <i>Kigelia pinnata</i> led to a significant reduction in both systolic and diastolic blood pressure in rats suffering from DOCA-salt-induced hypertension. …”

Table_1_Fermentation and Storage Characteristics of “Fuji” Apple Juice Using Lactobacillus acidophilus, Lactobacillus casei and Lactobacillus plantarum: Microbial Growth, Metabolis... by Jie Yang (121778)

“…After storage at 4°C for 30 days, the total amino acid content of fermented apple juice was significantly increased, although the viable cell counts and total phenolic content were decreased (p < 0.05). …”

original data.xlsx by Peng Shen (20145351)

“…<b>Research Results</b>: The results showed that the levels of inflammatory factors significantly decreased in the blood purification treatment group after treatment, with a notable reduction in hospitalization and ICU stay duration compared to the conventional treatment group. …”

Discovery of MKP10241, a Novel Small Molecule Targeting the GPR119/Incretin Axis to Treat Metabolic Disorders by Santosh Kumar Rai (22382996)

“…Chronic treatment of MKP10241 in DIO-mice exhibited marked reduction in body weight and feed intake at tested doses, which was associated with decreased blood glucose level, lipid parameters, and body fats. …”