Determinants of lipid lowering therapy intensification in very high risk patients with dyslipidaemia eligible for PCSK9 monoclonal antibodies: 1-year outcomes of the PERI-DYS study حسب Klaus G. Parhofer (12280424)

"…Lipid intensity changed in 22.3% of patients, with 14.8% experiencing intensification and 9.3% reduction. Significant predictors of LLT intensification included younger age (odds ratio (OR) for 60+ years 0.73), no baseline ezetimibe (OR 0.43), LDL-C > 100 mg/dL (OR 3.90), and statin intolerance (OR 0.68).…"

DataSheet2_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.xlsx حسب Yiyi Zuo (19945293)

"…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …"

Supplementary Material for: Comparing malposition and complications associated with Ultrasound-guided versus Radiography-guided central catheter tip-position in neonates: A Systema... حسب figshare admin karger (2628495)

"…Ultrasound-guided catheter tip-position significantly reduced malposition rates (3 RCTs, N=181, RR 0.51, CI 95% 0.37 to 0.70; 4 NRSs, N=1110, RR 0.25, CI 95% 0.11 to 0.57) and decreased the need for X-rays (2 RCTs, N=112, MD -1.22, CI 95% -2.32 to -0.11; 2 NRSs, N=401, MD -0.31, CI 95% -0.47 to -0.15). …"

Table 1_Proton therapy achieves high-dose tumor control with organ preservation in complex metastatic adenoid cystic carcinoma: a case report of a refractory patient with 16 pulmon... حسب Zejun Lu (2279458)

"…Follow-up PET/CT post-treatment demonstrated complete resolution of some bilateral pulmonary metastases, with marked reduction in size and decreased metabolism in the remaining nodules. …"

Data Sheet 1_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.docx حسب Man Zhao (314232)

"…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …"

Association between Lyn tyrosine kinase and renal injury in patients with systemic lupus erythematosus حسب Jian Sun (27858)

"…</p> <p>Compared to the HC group, SLE patients exhibited a decline in both Lyn mRNA and protein expression in PBMCs, with significant downregulation in the high SLEDAI group versus the low SLEDAI group and a notable reduction in the LN group relative to the non-LN group. …"

Data Sheet 1_Craving on the move: targeting smoking memories with a novel 3MDR–smoking cessation protocol.pdf حسب Annel P. Koomen (20406923)

"…Smoking cue–induced craving and physiological measures were assessed at baseline (T0) and 1 day after the intervention (T4), and smoking behavior was measured at T0 and 2-week (FU1) and 3-month (FU2) follow-up.</p>Results<p>Significant decreases in cue-induced craving from T0 to T4 and daily cigarette use from T0 to FU1 and FU2 were observed but not differ between the two experimental groups. …"

DataSheet1_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.pdf حسب Yiyi Zuo (19945293)

"…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …"

Image 6_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif حسب Ilmari Pyykkö (2855153)

"…Cognitive impairments were linked to the severity of these symptoms and the presence of constant dizziness. QoL was significantly lower among participants with constant dizziness, with factors like fatigue, depression, VDA, and hearing loss contributing to this reduction.…"

Data Sheet 1_Effect of Helicobacter pylori eradication on gastric cancer risk in patients with intestinal metaplasia or dysplasia: a meta-analysis of randomized controlled trials.d... حسب Qiang Fu (129583)

"…Further, if the study conducted in countries other than those in Asia, sample size <500, percentage of male <50.0%, follow-up duration <5.0 years, and low study quality, then there was no significant association between H. pylori eradication and a decreased risk of gastric cancer.…"

Data_Sheet_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.docx حسب Junjie Jiang (7255706)

"…A multivariable logistic regression model showed that each unit increase in CDAI corresponded to a 14.6% reduction in sleep disorder risk, exhibiting a nonlinear trend where the risk decreased until reaching the inflection point of −0.134. …"

Data_Sheet_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.docx حسب Junjie Jiang (7255706)

"…A multivariable logistic regression model showed that each unit increase in CDAI corresponded to a 14.6% reduction in sleep disorder risk, exhibiting a nonlinear trend where the risk decreased until reaching the inflection point of −0.134. …"

Image 4_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif حسب Ilmari Pyykkö (2855153)

"…Cognitive impairments were linked to the severity of these symptoms and the presence of constant dizziness. QoL was significantly lower among participants with constant dizziness, with factors like fatigue, depression, VDA, and hearing loss contributing to this reduction.…"

Image 5_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif حسب Ilmari Pyykkö (2855153)

"…Cognitive impairments were linked to the severity of these symptoms and the presence of constant dizziness. QoL was significantly lower among participants with constant dizziness, with factors like fatigue, depression, VDA, and hearing loss contributing to this reduction.…"

Table_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.docx حسب Junjie Jiang (7255706)

"…A multivariable logistic regression model showed that each unit increase in CDAI corresponded to a 14.6% reduction in sleep disorder risk, exhibiting a nonlinear trend where the risk decreased until reaching the inflection point of −0.134. …"

Ameliorating role of co-administration of granulocyte colony stimulating factor and sodium bicarbonate on the skeletal muscle of a rat model of chronic kidney disease (A histologic... حسب Fayza E. Ahmed (20487163)

"…The CKD group revealed a significant increase in MDA and TNF-α. Furthermore, features of renal injury, muscle degenerative changes, increased collagen and decreased CD34 and myogenin expression were observed. …"

Image 1_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif حسب Ilmari Pyykkö (2855153)

"…Cognitive impairments were linked to the severity of these symptoms and the presence of constant dizziness. QoL was significantly lower among participants with constant dizziness, with factors like fatigue, depression, VDA, and hearing loss contributing to this reduction.…"

Image 2_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif حسب Ilmari Pyykkö (2855153)

"…Cognitive impairments were linked to the severity of these symptoms and the presence of constant dizziness. QoL was significantly lower among participants with constant dizziness, with factors like fatigue, depression, VDA, and hearing loss contributing to this reduction.…"

Supplementary file 1_Spatial-temporal evolution characteristics and driving factors of carbon emission prediction in China-research on ARIMA-BP neural network algorithm.pdf حسب Sanglin Zhao (20915732)

"…Therefore, it is of great significance to analyze the characteristics and driving factors of temporal and spatial evolution on the basis of effective calculation and prediction of carbon emissions in various provinces for promoting high-quality economic development and realizing carbon emission reduction. …"

Data Sheet 1_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.pdf حسب Ilmari Pyykkö (2855153)

"…Cognitive impairments were linked to the severity of these symptoms and the presence of constant dizziness. QoL was significantly lower among participants with constant dizziness, with factors like fatigue, depression, VDA, and hearing loss contributing to this reduction.…"