Data Sheet 4_Beyond salt tolerance: SOS1-13’s pivotal role in regulating the immune response to Fusarium oxysporum in Solanum phureja.docx by Liqin Liang (652560)

“…Conversely, silencing the ortholog gene NbSOS1-13 in Nicotiana benthamiana showed more accumulation of ROS, serious cell necrosis, reduced activities of SOD and CAT, significantly increased MDA level, obvious leaf wilting, decreased tolerance to infection, and reduced leaf stomatal closure rate and accelerated stomatal area. …”

Data Sheet 1_Personalized temporal interference stimulation targeting striatum reduces functional stability and dynamic connectivity variability in the sensorimotor network.docx by Dongsheng Tang (5526149)

“…Seed-based dFC variability in the right striatum was measured as the standard deviation of dFC across windows.</p>Results<p>(1) Functional stability: TI stimulation significantly decreased functional stability in bilateral SMA regions (predominantly SMA proper, with parts of pre-SMA) compared to Sham and baseline conditions (P < 0.01). (2) Dynamic functional connectivity: TI stimulation reduced dFC variability between the right striatum and left SMA region (predominantly SMA proper, with parts of pre-SMA) compared to baseline (P < 0.01). (3) Safety: No adverse cognitive effects or side effects were observed, with good blinding effectiveness maintained throughout the study.…”

Raw data for figures. by Erdyni N. Tsitsikov (20384719)

“…Histological examination of anterior thalamic nuclei demonstrated decreased myelination of anteroventral nuclei but not of anterodorsal nuclei in P23 <i>Rik</i>^<i>null</i> mice. …”

Table 1_Beyond salt tolerance: SOS1-13’s pivotal role in regulating the immune response to Fusarium oxysporum in Solanum phureja.docx by Liqin Liang (652560)

“…Conversely, silencing the ortholog gene NbSOS1-13 in Nicotiana benthamiana showed more accumulation of ROS, serious cell necrosis, reduced activities of SOD and CAT, significantly increased MDA level, obvious leaf wilting, decreased tolerance to infection, and reduced leaf stomatal closure rate and accelerated stomatal area. …”

Table 5_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.xlsx by Ying Dong (41989)

“…MR analysis was then performed using summary statistics from the EBI database (n = 484,598) to assess the putative relationships between candidate genes and psoriasis risk.</p>Results<p>Seven genetically informed candidate genes were identified as being significantly associated with psoriasis susceptibility. …”

Uncropped DNA gel used for Fig 1B. by Erdyni N. Tsitsikov (20384719)

“…Histological examination of anterior thalamic nuclei demonstrated decreased myelination of anteroventral nuclei but not of anterodorsal nuclei in P23 <i>Rik</i>^<i>null</i> mice. …”

Data Sheet 1_Serum stromal cell-derived factor 1α as a prognostic indicator in elderly patients with acute myeloid leukemia receiving CAG-based chemotherapy.docx by Zhenzhen Wang (250368)

“…Patients received CAG (cytarabine, aclarubicin, and G‐CSF)-based chemotherapy, and serum SDF-1α levels were assessed using ELISA.</p>Results<p>Serum SDF-1α levels were significantly elevated in elderly AML patients compared to controls (p < 0.001). …”

Table 1_Conditional knockdown of hepatic PCSK9 ameliorates high-fat diet-induced liver inflammation in mice.docx by Xue-Ying Zhang (144147)

“…Moreover, the findings were verified in vitro using HepG2 cells.</p>Results and Discussion<p>Conditional knockdown of hepatic PCSK9 remarkably decreased plasma levels of total cholesterol and alleviated hyperlipidemia-induced liver injury. …”

DataSheet2_Treatment and molecular analysis of bullous pemphigoid with tofacitinib: a case report and review of current literature.xlsx by Xiang Li (114679)

“…Immunohistochemical analysis showed tofacitinib significantly decreased the pSTAT3 and pSTAT6 levels in the skin lesions of this patient. …”

Image 2_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif by Ying Dong (41989)

“…MR analysis was then performed using summary statistics from the EBI database (n = 484,598) to assess the putative relationships between candidate genes and psoriasis risk.</p>Results<p>Seven genetically informed candidate genes were identified as being significantly associated with psoriasis susceptibility. …”

DataSheet1_Scutellarein ameliorates dextran sulfate sodium-induced ulcerative colitis by inhibiting colonic epithelial cell proinflammation and barrier disruption.DOC by Qinglian Tang (9162473)

“…IL-1β-treated HT-29 cells was used for mechanical investigation.</p>Results<p>Gavage of Scu significantly decreased the DAI score, improved colon shortening, ameliorated the pathological score in DSS-treated mice with better efficacy than the positive drug, 5-aminosalicylic acid. …”

Table 1_Association between red blood cell distribution width and encephalitis based on the pediatric intensive care unit database: a cross-sectional study.docx by Weichao He (16832265)

“…Multivariate regression models revealed that encephalitis in Chinese children was significantly decreased by 18% with 1% increase in RDW after adjusting for all covariates (Adjusted OR = 0.82, 95% CI: 0.73–0.92). …”

Data Sheet 1_Loss of a primary cilia protein ARL13B promotes TGFβ-1 induced EMT of RPE in proliferative vitreoretinopathy via increasing Smad3 expression.pdf by Wenjun Sui (22776290)

“…An intravitreal injection mouse model of PVR was used to investigate the role of ARL13B in PVR formation.</p>Results<p>Immunofluorescence revealed significantly reduced ARL13B levels in α-SMA-positive cells as compared with Pan-CK-positive cells in an epiretinal membrane derived from retinal tears. …”

Supplementary file 1_Effects of Lactiplantibacillus plantarum DSM 33464 in children with elevated blood lead levels: a randomized, double-blind, placebo-controlled study.docx by Wenjing Ji (720509)

“…Introduction<p>Approximately one-third of the world’s children have elevated blood lead levels (BLLs), which may lead to often-irreversible decreased intelligence, behavioral difficulties, and learning problems. …”

Data Sheet 1_miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling.pdf by Juanjuan Zhang (432819)

“…We evaluated disease activity index (DAI), colonic inflammation, and the expression of inflammatory mediators, peroxisome proliferator-activated receptor gamma (PPAR-γ) and forkhead box transcription factor O1 (FOXO1). </p>Results<p>Histopathological analysis showed that miR-223 agomir significantly attenuated DSS-induced colon damage. …”

Data Sheet 1_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.pdf by Miguel Ângelo-Dias (20936444)

“…We evaluated 74 lymphocyte subsets, including follicular and non-follicular CD4 and CD8 T cells, and functional markers CD69 and PD-L1, under basal and stimulated conditions.</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …”

Data Sheet 4_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.pdf by Miguel Ângelo-Dias (20936444)

“…We evaluated 74 lymphocyte subsets, including follicular and non-follicular CD4 and CD8 T cells, and functional markers CD69 and PD-L1, under basal and stimulated conditions.</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …”

Table 4_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.xlsx by Ying Dong (41989)

“…MR analysis was then performed using summary statistics from the EBI database (n = 484,598) to assess the putative relationships between candidate genes and psoriasis risk.</p>Results<p>Seven genetically informed candidate genes were identified as being significantly associated with psoriasis susceptibility. …”

Table1_SMAD4 enhances the cytotoxic efficacy of human NK cells against colorectal cancer cells via the m6A reader YTHDF2.docx by Xinxin Li (281237)

“…</p>Methods<p>We examined the regulatory mechanism of SMAD4-mediated NK cell cytotoxicity on CRC by utilizing various experimental techniques, such as qRT-PCR, flow cytometry.</p>Results<p>Our findings revealed that the expression of SMAD4 is decreased in NK cells within the TME of human CRC. …”

Image 3_Natural killer cell as a potential predictive biomarker for early immune checkpoint inhibitor-associated cardiovascular adverse events: a retrospective cohort study.tif by Yujuan Wu (2249857)

“…Propensity score matching (PSM) was used to validate the predictive value of baseline NK cell proportion for CAVEs.</p>Results<p>ScRNA-seq data revealed decreased CD8+ T and B cell proportions in the CVAEs group, while NK cell proportions increased. …”