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significant results » significant reductions (Expand Search), significant reduction (Expand Search)
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17601
Table 1_Characteristics of the vaginal microbiota and vaginal metabolites in women with cervical dysplasia.docx
Published 2024“…Correlation analysis revealed positive associations between CC group-decreased Lactobacillus abundance and CC group-decreased metabolites. …”
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17602
Mendelian randomization analysis revealed that albuminuria is the key factor affecting socioeconomic status in CKD patients
Published 2025“…In the multivariable MR analysis, both CKD (OR = 0.867, 95% CI: 0.786–0.957, <i>p</i> = 0.0045) and eGFR (OR = 0.065, 95% CI: 0.010–0.437, <i>p</i> = 0.0049) exhibited significant effects on income. This study underscores that higher albuminuria levels in CKD patients are associated with decreased income and emphasizes the importance of effective management and treatment of albuminuria in CKD patients to mitigate both social and personal economic burdens.…”
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17603
Data Sheet 1_Physicochemical property and microbial community characteristics of the casing soil for cultivating Oudemansiella raphanipes.pdf
Published 2024“…Urease activity peaked [1.56 g/(g·h)] at A1, and it decreased gradually (p < 0.01). Polyphenol oxidase activity was significantly higher at A2 [0.95 g/(g·h)] than at the other stages and was significantly lower at A1 [0.06 g/(g·h)]. …”
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17604
Data Sheet 1_The role of neutrophils and NETosis in lipopolysaccharide exacerbated asthmatic airway inflammation.docx
Published 2025“…Suppressing NETs yielded similar results to decreasing neutrophils.</p>Conclusion<p>Our results indicate that NETs are involved in the pathogenesis of LPS exacerbated asthmatic airway inflammation, and targeting the NETosis function of neutrophils may represent an effective therapeutic approach.…”
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17605
Image 1_Innate immune pathway activation to modulate mesenchymal stromal cell (MSC) interactions with synovium and cartilage.jpeg
Published 2025“…Bulk RNA sequencing was performed on MSC and joint cell lines via an Illumina based platform.</p>Results<p>TLR-MSC-CM decreased IL-1β (p = 0.02), IL-6 (p = 0.02) secretion by synoviocytes and IL-18 secretion by activated chondrocytes (p = 0.002). …”
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17606
<b>Climate warming, rather than nitrogen deposition, reduces plant diversity and increases community homogenization in a desert steppe</b>
Published 2025“…Over this period (2006–2022), warming (mean annual temperature + 1.4°C) significantly decreased species richness and functional α-diversity throughout the experiment, whereas its effects on phylogenetic α-diversity and community phylogenetic structure were significant only before 2015 and disappeared thereafter, likely due to an extreme drought that reset the community composition. …”
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17607
Data Sheet 1_Differential impacts of jogging and rope skipping in college students in China based on physical test score: a randomized controlled trial baseline indicator compariso...
Published 2025“…Tests and questionnaires were conducted before and right after the intervention, and a questionnaire survey was conducted again half a year after the intervention.</p>Results<p>The results showed that the standing long jump performance and the cardiopulmonary function in the jogging group were significantly improved after the intervention, the average score of standing long jump increased from 72.00 to 76.45 and the mean systolic blood pressure decreased from 125.07 to 121.24 (t = 3.048, 2.139, p = 0.005, 0.041). …”
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17608
Table 1_Differential impacts of jogging and rope skipping in college students in China based on physical test score: a randomized controlled trial baseline indicator comparison in...
Published 2025“…Tests and questionnaires were conducted before and right after the intervention, and a questionnaire survey was conducted again half a year after the intervention.</p>Results<p>The results showed that the standing long jump performance and the cardiopulmonary function in the jogging group were significantly improved after the intervention, the average score of standing long jump increased from 72.00 to 76.45 and the mean systolic blood pressure decreased from 125.07 to 121.24 (t = 3.048, 2.139, p = 0.005, 0.041). …”
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17609
Data Sheet 1_ClpB affects biofilm formation in methicillin-resistant Staphylococcus aureus.pdf
Published 2025“…A mouse skin infection model was subsequently employed to assess wound healing, histopathological changes, and the expression levels of inflammatory factors.</p>Results<p>The results showed that compared with the wild strain (WT), the biomass of ΔclpB biofilm was significantly reduced (p < 0.0001), the structure was damaged and the production of extracellular matrix (eDNA, polysaccharides, proteins) decreased. …”
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17610
Data Sheet 2_ClpB affects biofilm formation in methicillin-resistant Staphylococcus aureus.docx
Published 2025“…A mouse skin infection model was subsequently employed to assess wound healing, histopathological changes, and the expression levels of inflammatory factors.</p>Results<p>The results showed that compared with the wild strain (WT), the biomass of ΔclpB biofilm was significantly reduced (p < 0.0001), the structure was damaged and the production of extracellular matrix (eDNA, polysaccharides, proteins) decreased. …”
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17611
Image 2_Phage therapy for extensively drug resistant Acinetobacter baumannii infection: case report and in vivo evaluation of the distribution of phage and the impact on gut microb...
Published 2024“…In fecal samples, a significant reduction in the Ct value of phages was observed following both phases of bacteriophage treatment, with values decreasing from 35.5 to 22.5 and from 32.6 to 22.7, respectively. …”
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17612
Effects of repeated intravenous esketamine administration on affective biases
Published 2025“…</p> <p>66.7% participants who received at least five infusions (<i>n</i> = 12) showed significant improvement. Emotion recognition improved for all emotions except sadness, where accuracy decreased, particularly for low-intensity expressions (<i>p</i> = .007, d = −1.09). …”
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17613
Image 1_Phage therapy for extensively drug resistant Acinetobacter baumannii infection: case report and in vivo evaluation of the distribution of phage and the impact on gut microb...
Published 2024“…In fecal samples, a significant reduction in the Ct value of phages was observed following both phases of bacteriophage treatment, with values decreasing from 35.5 to 22.5 and from 32.6 to 22.7, respectively. …”
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17614
Data Sheet 1_Effects of chili straw on rumen fermentation, meat quality, amino acid and fatty acid contents, and rumen bacteria diversity in sheep.docx
Published 2025“…Key findings include: (1) No significant differences were observed in rumen pH, NH<sub>3</sub>-N, or acetic acid-to-propionic acid ratio across groups (P > 0.05). (2) Rumen microbial diversity indices did not vary significantly between groups (P > 0.05), though the relative abundance of Firmicutes and Proteobacteria increased, and Bacteroidota decreased in CS-fed groups, with specific genus-level changes. (3) Carcass weight decreased in the CS20% group (P < 0.01). (4) Cooking loss decreased in CS10%, 15%, and 20% groups (P < 0.05), and meat redness increased in CS15% and 20% groups (P < 0.01). (5) Saturated fatty acids decreased, while the PUFA/SFA ratio and amino acid profiles, including sulfur-containing amino acids (SAA), dibasic amino acids (DAA), essential amino acids (EAA), and total amino acids (TAA), increased with CS, with a significant rise in Gly content in the CS15% group (P < 0.05). …”
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17615
Raw data
Published 2025“…By integrating the transcriptomics and metabolomics data, we identified 55 genes, including glucose kinase (GCK) and phosphoglycerate mutase 1 (PGAM1), which are involved in metabolic pathways related to glycolysis, regulation of glycolytic processes, and carbohydrate phosphorylation. The results of this study indicate that compared to the model group, the content of regulatory enzymes and main products (mainly GCK) of the glycolytic pathway significantly decreased after administration of Rb1, and the key enzyme ACC for fatty acid synthesis also significantly decreased.…”
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17616
DataSheet2_D-mannose reduces oxidative stress, inhibits inflammation, and increases treg cell proportions in mice with ulcerative colitis.xlsx
Published 2024“…D-mannose treatment significantly reduced inflammation by decreasing the expression of proinflammatory cytokines and inflammation mediators. …”
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17617
DataSheet1_D-mannose reduces oxidative stress, inhibits inflammation, and increases treg cell proportions in mice with ulcerative colitis.pdf
Published 2024“…D-mannose treatment significantly reduced inflammation by decreasing the expression of proinflammatory cytokines and inflammation mediators. …”
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17618
Data Sheet 1_Splenic volume as a predictor of survival in cancer patients treated with immune checkpoint inhibitors.docx
Published 2025“…The primary metrics assessed were hazard ratios (HR) for both OS and PFS, with pooled estimates and corresponding 95% confidence intervals (CIs) calculated.</p>Results<p>Within our study population, findings demonstrated a significantly decreased OS (HR: 2.02, 95% CI: 1.08–3.77, p = 0.027) and PFS (HR: 1.84, 95% CI: 1.05–3.21, p = 0.032) in HCC patients with a high baseline spleen volume, compared to individuals with lower spleen volumes. …”
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17619
Modulation of renal inflammation and tubular injury by calcitriol in patients with early diabetic kidney disease: a randomized controlled trial
Published 2025“…Although UACR decreased more in the calcitriol group, the difference was not statistically significant (<i>p</i> = 0.099). …”
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17620
Data Sheet 1_Polydatin combined with hawthorn flavonoids alleviate high fat diet induced atherosclerosis by remodeling the gut microbiota and glycolipid metabolism.pdf
Published 2025“…The experiment lasted for 24 weeks.</p>Results<p>Polydatin combined with hawthorn flavonoids administration significantly reduced lipid and inflammatory cytokine levels, meanwhile, the atherosclerotic lesions in a high-fat diet-induced ApoE<sup>−/−</sup> mice were significantly decreased. …”