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significant results » significant reductions (Expand Search), significant reduction (Expand Search)
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18261
Effect of miR-7974 mimic transfection on proliferation of MDA-MB-453 cells together with changes in protein and gene expression levels of LC3B.
Published 2025“…<b>(B)</b> The fold change of total protein levels of LC3B between negative control/cells only samples and miR-7974-treated samples were statistically significant. <b>(C)</b> The gene expression levels of <i>LC3B</i> were decreased 72h after miR-7974 transfection of MBA-MB-453 cells compared to the negative control/cells-only samples. …”
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18262
The impact of refractive error correction on health-related quality of life in nursing home residents in Armenia
Published 2025“…Those who had not corrected their vision reported no significant improvement in both PHC and MHC. There were no significant differences in baseline to follow-up mean change scores for PHC and MHC between those who corrected their vision and those who had not.…”
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18263
Discriminatory learning preferentially enhances reward associated input.
Published 2025“…(E) Fraction of glomeruli with significant changes post learning. Yellow: increased, dark grey: decreased, light grey: unchanged. …”
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18264
Figure 4 from PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma
Published 2025“…However, the levels of DX5+ (NKT cells) decreased slightly but significantly in TI (<i>P</i> = 0.017). …”
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18265
Supplementary file 1_Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.tif
Published 2025“…CYT treatment regulated the RNA and protein levels of epithelial mesenchymal transition (EMT) biomarkers, suppressed the sphere formation ability and expression of cancer stem cell biomarkers in drug resistant BC cells. Results from transcriptome sequencing analysis and experiments identified significantly decreased SRSF1 level in drug resistant cells after CYT treatment. …”
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18266
Table 1_Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.docx
Published 2025“…CYT treatment regulated the RNA and protein levels of epithelial mesenchymal transition (EMT) biomarkers, suppressed the sphere formation ability and expression of cancer stem cell biomarkers in drug resistant BC cells. Results from transcriptome sequencing analysis and experiments identified significantly decreased SRSF1 level in drug resistant cells after CYT treatment. …”
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18267
Table 2_Ipriflavone ameliorates intervertebral disc degeneration by inhibiting osteoporosis of vertebral body and pyroptosis of the nucleus pulposus in instability of lumbar spine...
Published 2025“…Furthermore, IP ameliorated the cartilage extracellular matrix degradation, significantly increased Aggrecan and Col II expression and decreased the expression of MMP13 and ADAMTS-4. …”
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18268
Supplementary file 2_Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.tif
Published 2025“…CYT treatment regulated the RNA and protein levels of epithelial mesenchymal transition (EMT) biomarkers, suppressed the sphere formation ability and expression of cancer stem cell biomarkers in drug resistant BC cells. Results from transcriptome sequencing analysis and experiments identified significantly decreased SRSF1 level in drug resistant cells after CYT treatment. …”
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18269
Data Sheet 1_Knockdown of annexin A2 enhances the host cell apoptosis induced by Eimeria tenella.zip
Published 2025“…Following ANXA2 knockdown, the cell apoptosis rate, caspase-3 activity, and Bax expression levels were significantly increased (P < 0.01), whereas the infection rate and Bcl-2 expression levels were significantly decreased (P < 0.01) compared to the group infected with E. tenella alone. …”
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18270
Table 1_Ipriflavone ameliorates intervertebral disc degeneration by inhibiting osteoporosis of vertebral body and pyroptosis of the nucleus pulposus in instability of lumbar spine...
Published 2025“…Furthermore, IP ameliorated the cartilage extracellular matrix degradation, significantly increased Aggrecan and Col II expression and decreased the expression of MMP13 and ADAMTS-4. …”
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18271
Supplementary file 3_Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.tif
Published 2025“…CYT treatment regulated the RNA and protein levels of epithelial mesenchymal transition (EMT) biomarkers, suppressed the sphere formation ability and expression of cancer stem cell biomarkers in drug resistant BC cells. Results from transcriptome sequencing analysis and experiments identified significantly decreased SRSF1 level in drug resistant cells after CYT treatment. …”
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18272
Image 1_First-trimester choroid plexus-to-head ratio: a novel sonographic marker for the early detection of fetal central nervous system malformations.jpeg
Published 2025“…Compared with the control group, scatter diagrams and box-and-whiskers plots showed ventriculomegaly (VM) fetuses had significantly decreased CPA/HA and CPL/OFD ratios (p < 0.001), but increased CFD/OFD and HC/AC ratios (p < 0.001). …”
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18273
Effects of exogenous phytohormone 5-ALA on fruit quality and volatile metabolites of ' Meizao ' sweet cherry
Published 2025“…At the same time, the anthocyanin content decreased significantly by 64.47% compared with the control, whereas the contents of flavonoids, total phenols, and tannins increased by 114.62%, 7.80%, and 1.67%, respectively. …”
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18274
Supplementary Material for: Effect of Amla extract on Body Mass Index, waist circumference, total body fat, visceral fat, skeletal muscle mass, body age and related parameters: A r...
Published 2025“…Efficacy assessments included anthropometric measurements, Bioelectric Impedance analysis, lipid profile analysis, and the Global Physical Activity Questionnaire (GPAQ) at scheduled visits. Results: Supplementation with 1 gram of AMX-160 (500 mg twice daily) significantly (p<0.05) reduced visceral fat, increased skeletal muscle mass, and decreased subcutaneous fat. …”
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18275
Image 2_First-trimester choroid plexus-to-head ratio: a novel sonographic marker for the early detection of fetal central nervous system malformations.jpeg
Published 2025“…Compared with the control group, scatter diagrams and box-and-whiskers plots showed ventriculomegaly (VM) fetuses had significantly decreased CPA/HA and CPL/OFD ratios (p < 0.001), but increased CFD/OFD and HC/AC ratios (p < 0.001). …”
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18276
Cholecalciferol alleviates testicular dysfunction in experimental hyperthyroidism via antioxidant, anti-inflammatory and antiapoptotic effects
Published 2025“…It significantly decreased the levels of serum inflammatory markers and malondialdehyde levels. …”
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18277
Data Sheet 1_Supplementary far-red light enhances the quality and root development of double-root-cutting grafted watermelon seedlings.docx
Published 2025“…These results demonstrate that supplementary FR light significantly promotes rooting and growth of DRC grafted watermelon seedlings. …”
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18278
Supplementary file 1_Ultrafine garlic powder alleviates non-alcoholic steatohepatitis by inhibiting hepatocyte ferroptosis and modulating ERK-dependent oxidative stress.docx
Published 2025“…Fibrosis-related mRNA and pro-inflammatory mRNA expression were significantly decreased. Western blot results showed that UGP significantly inhibited the activation of p-ERK signaling. …”
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18279
Table 1_Organic fertilizer in combination with zeolite enhanced maize yield with lower greenhouse gas emissions in sandy loam soil in North China.docx
Published 2025“…</p>Methods<p>In the present study, a 3-year maize field experiment was conducted on a sandy loam soil in the North China Plain with five treatments: no added fertilizer (control, CK), synthetic fertilizer (SF), organic fertilizer replacing 30% synthetic N fertilizer (OF), synthetic fertilizer with zeolite (ZSF), and organic fertilizer with zeolite (ZOF).</p>Results<p>Results showed that, compared with the SF treatment, the ZOF treatment significantly increased yield by 14.72–23.61% in each of the 3 years, ZSF by 13.91–15.59% in 2022 and 2023, and OF by 16.92% in 2023. …”
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18280
<b>Antiretroviral therapy </b><b>does not correct the dysregulations of plasma virome and cytokines induced by HIV-1</b>
Published 2024“…These results indicate that ART does not significantly correct the virome and cytokine dysregulations associated with HIV-1 infection.…”