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significant results » significant reductions (Expand Search), significant reduction (Expand Search)
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19101
Presentation 1_Germination responses of native fire ephemerals of Patagonian grasslands to smoke water and karrikinolide.zip
Published 2025“…This inhibitory effect decreased with storage time, suggesting that toxic compounds in SW degrade over time. …”
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19102
Image 5_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.tif
Published 2025“…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”
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19103
Information of chemicals used in this study.
Published 2024“…In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …”
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19104
Table 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
Published 2025“…A series of molecular and biochemical experiments were carried out in PCa cell lines to investigate the mechanism underlying PCP4-mediated tumor suppression.</p>Results<p>(1) PCP4 gene loss occurs at high frequency in PCa patients, and decreased expression of PCP4 correlates with poor prognosis of PCa, particularly CRPC development; (2) TMPRSS2-ERG fusion frequently co-occurs with PCP4 deletion; (3) PCP4 suppresses prostate cancer progression in vitro and in vivo; (4) PCP4 is an androgen receptor (AR) suppressed gene; (5) PCP4 was involved in the stabilization of CAMKK2 protein; (6) PCP4 inhibits PCa progression by regulating Ca<sup>2+</sup>/CAMKK2/AMPK/AR signaling axis.…”
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19105
Table 1_Gandouling ameliorates Wilson’s disease-associated liver fibrosis in mice with associated faecal microbiome and metabolome remodeling.xlsx
Published 2025“…Additionally, to detect alterations in the intestinal bacterial composition and metabolites, faecal samples were examined using non-targeted metabolomics and 16S rRNA sequencing.</p>Results<p>The administration of GDL demonstrated anti-fibrotic effects on the liver, decreased serum inflammatory markers, ameliorated liver histopathology, and restored ileal permeability in the model group, as compared to the control group. …”
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19106
Table 1_Optimization of ultrasonic-assisted extraction of total flavonoids from Zanthoxylum bungeanum residue by response surface methodology and evaluation of its algicidal proper...
Published 2025“…Meanwhile, treatment with Z. bungeanum residue extract at doses of 40.0 mg/L significantly decreased the Fv/Fm and PIabs values of T. obliquus by 24.36 and 88.87% at 50 h, respectively. …”
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19107
Table 1_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.xlsx
Published 2025“…Bioinformatics analysis identified potential target genes for GA’s cardioprotection, which were subsequently validated using pAD/TSPO (for overexpression) and pAD/FTMT-shRNA (for silencing) constructs.</p>Results<p>GA treatment decreased PTGS2, lactate dehydrogenase, malondialdehyde, ferrous iron, ROS, and oxidized glutathione disulfide (GSSG) levels and increased cell viability, glutathione (GSH) levels, the GSH/GSSG ratio, and GPX4 protein levels in the injury models. …”
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19108
Oligonucleotides used for amplification.
Published 2024“…In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …”
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19109
Image 9_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg
Published 2025“…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”
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19110
Data Sheet 1_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.pdf
Published 2025“…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”
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19111
Data Sheet 13_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf
Published 2025“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
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19112
Image 2_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg
Published 2025“…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”
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19113
Table 2_Deletion of the GntR8 transcriptional regulator impairs Brucella abortus intracellular survival and virulence by modulating stress response genes.docx
Published 2025“…In this study, we generated a gntR8 (BAB_RS24500) deletion strain (ΔgntR8) in B. abortus 2308 and systematically investigated its role in virulence. The results demonstrate that deletion of gntR8 markedly impairs intracellular survival of B. abortus in RAW264.7 cells and significantly reduces virulence in a mouse infection model. …”
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19114
Image 5_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif
Published 2025“…EA was applied at different frequencies to the Zusanli (ST36) acupoint for 7 days post-METH administration.</p>Results<p>Behavioral tests revealed that low-frequency EA significantly alleviated depressive-like behaviors and cognitive impairment. …”
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19115
Image 5_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif
Published 2025“…Assessments included behavioral assays (social interaction, repetitive behaviors), hippocampal cytokine profiling (IL-6, TNF-α), 16S rRNA sequencing for gut microbiota analysis, immunohistochemistry (Iba1<sup>+</sup> microglia), and ultrastructural synaptic analysis.</p>Results<p>3KO-hiPSC-NSC treatment significantly ameliorated VPA-induced ASD-like behaviors. …”
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19116
Data Sheet 1_The differential effect of optogenetic serotonergic manipulation on sustained motor actions and waiting for future rewards in mice.docx
Published 2024“…These results revealed that the necessity of motor actions may increase motivation for delayed rewards and that DRN serotonergic neurons more significantly promote waiting rather than persistent motor actions for future rewards.…”
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19117
Supplementary Material for: Glucosamine use reduces the risk of first-ever optic neuritis: A nationwide 16-year longitudinal analysis
Published 2024“…Outcomes include the annual trend of first-ever ON incidence, crude/adjusted hazard ratios (HRs) of incident ON stratified by sociodemographic characteristics and comorbidities. Results: Glucosamine exposure has been significantly associated with reduced ON incidence (Log-rank p < 0.001) since the fifth year of clinical surveillance. …”
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19118
Data Sheet 1_Coordinated development of ecosystem services and human well-being is increasing in the Yellow River Basin, though some regions lag behind.docx
Published 2025“…The relationship between support service and HWB in Shandong deteriorated, and the relationship between the ESV and HWB in Gansu exhibited a serious lag in ESV and will remain in an uncoordinated state for the next 20 years. Our approaches and results have guiding significance for promoting the coordinated development of HWB and ESs and substantiating the SDGs.…”
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19119
Data Sheet 2_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf
Published 2025“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
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19120
Raw Data from Bioassays and R Code for Statistical Analyses in Manuscript Submitted to the <i>Journal of Chemical Ecology</i>
Published 2024“…We measured the behavioral responses of ant workers to dummies coated with various hydrocarbons, after presenting them with dummies treated with methylalkanes and a sucrose solution as a reward. The results showed that ants previously exposed to 2-methyltetracosane (2-MeC24) decreased their aggressiveness not only toward 2-MeC24 but also toward 2-MeC26, despite the difference in the chain lengths. …”