Image 13_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

“…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”

Data Sheet 10_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Image 4_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif by Caixia Wu (8959697)

“…Assessments included behavioral assays (social interaction, repetitive behaviors), hippocampal cytokine profiling (IL-6, TNF-α), 16S rRNA sequencing for gut microbiota analysis, immunohistochemistry (Iba1⁺ microglia), and ultrastructural synaptic analysis.</p>Results<p>3KO-hiPSC-NSC treatment significantly ameliorated VPA-induced ASD-like behaviors. …”

Image 1_Atractylenolide-I prevents abdominal aortic aneurysm formation through inhibiting inflammation.tif by Shuxiao Chen (7339340)

“…</p>Results<p>ATL-I inhibited the dilatation of the abdominal aorta and decreased the incidence of AAA. …”

Table 1_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.xlsx by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Table 2_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.xlsx by Chenchao Zou (22768010)

“…Bioinformatics analysis identified potential target genes for GA’s cardioprotection, which were subsequently validated using pAD/TSPO (for overexpression) and pAD/FTMT-shRNA (for silencing) constructs.</p>Results<p>GA treatment decreased PTGS2, lactate dehydrogenase, malondialdehyde, ferrous iron, ROS, and oxidized glutathione disulfide (GSSG) levels and increased cell viability, glutathione (GSH) levels, the GSH/GSSG ratio, and GPX4 protein levels in the injury models. …”

Image 3_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…EA was applied at different frequencies to the Zusanli (ST36) acupoint for 7 days post-METH administration.</p>Results<p>Behavioral tests revealed that low-frequency EA significantly alleviated depressive-like behaviors and cognitive impairment. …”

Table 1_Therapeutic potential of Cervi Cornus Colla in zebrafish bone injury: implications for aquaculture.docx by Fengxia Xu (20175965)

“…In Tg (mpeg1: EGFP) zebrafish, CCC treatment significantly decreased macrophages-associated green fluorescence, suggesting that the extract suppressed the activation of macrophages caused by LPS. …”

Table 1_Deletion of the GntR8 transcriptional regulator impairs Brucella abortus intracellular survival and virulence by modulating stress response genes.xlsx by Shuwen Li (5058398)

“…In this study, we generated a gntR8 (BAB_RS24500) deletion strain (ΔgntR8) in B. abortus 2308 and systematically investigated its role in virulence. The results demonstrate that deletion of gntR8 markedly impairs intracellular survival of B. abortus in RAW264.7 cells and significantly reduces virulence in a mouse infection model. …”

Data Sheet 1_Cordycepin attenuates NLRP3/Caspase-1/GSDMD-mediated LPS-induced macrophage pyroptosis.pdf by Zige Liu (20724752)

“…Cordycepin pre-treatment significantly reduced ROS levels and XO activity, inhibited the expression of NLRP3, cleaved-Caspase-1, and cleaved-GSDMD, and decreased pyroptosis-associated inflammatory cytokines IL-1β and IL-18, along with Caspase-1 activity. …”

Data Sheet 6_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.xlsx by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Table 1_Alterations in gut–kidney axis indicators and TMAO-related biomarkers in elderly patients with hypertensive nephropathy.xlsx by Ziyi Li (349831)

“…Urinary TMAO was significantly decreased in both hypertensive groups, while serum TMAO remained unchanged. …”

Data from: Decade-long bird trends in China: Stable species richness but increasing biotic homogenization by Jiekun He (20964269)

“…In contrast, functional richness increased significantly (Zr = 0.122, 95% CI = [0.016; 0.227]). …”

Data Sheet 5_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.xlsx by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Data Sheet 10_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”

Table 1_Intramuscular iron supplementation enhances intestinal barrier function in weaned piglets challenged with enterotoxigenic Escherichia coli.docx by Chenying Tian (21731474)

“…After challenge, piglets were euthanized, and serum and small intestinal tissues were collected for biochemical analysis, histological examination, inflammatory response assessment, gut microbiota profiling, and iron metabolism evaluation.</p>Results<p>Intramuscular iron supplementation alleviated the clinical symptoms of bacterial infection, decreasing the diarrhea rate by 53% and mitigating the inflammatory response with lower serum levels of pro-inflammatory cytokines, such as TNF-α, IL-6, and IL-8. …”

Image 3_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin... by Yun Zhao (48978)

“…In vitro experiments validated CA9 as a promising therapeutic target, with its knockdown significantly inhibiting OSCC cell proliferation and migration.…”

Effect of CBZ pretreatment on HSR-induced histological damage in the lungs of rats with acute lung injury. by Yaqiang Li (7423778)

“…Consistent with histopathological results, lung injury scores were elevated in the HSR group; however, administration of CBZ markedly decreased these scores. …”

Image 1_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…EA was applied at different frequencies to the Zusanli (ST36) acupoint for 7 days post-METH administration.</p>Results<p>Behavioral tests revealed that low-frequency EA significantly alleviated depressive-like behaviors and cognitive impairment. …”

Data Sheet 2_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf by Didar Murad (12220805)

“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”