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significant results » significant reductions (Expand Search), significant reduction (Expand Search)
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19181
Table 3_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
Published 2025“…A series of molecular and biochemical experiments were carried out in PCa cell lines to investigate the mechanism underlying PCP4-mediated tumor suppression.</p>Results<p>(1) PCP4 gene loss occurs at high frequency in PCa patients, and decreased expression of PCP4 correlates with poor prognosis of PCa, particularly CRPC development; (2) TMPRSS2-ERG fusion frequently co-occurs with PCP4 deletion; (3) PCP4 suppresses prostate cancer progression in vitro and in vivo; (4) PCP4 is an androgen receptor (AR) suppressed gene; (5) PCP4 was involved in the stabilization of CAMKK2 protein; (6) PCP4 inhibits PCa progression by regulating Ca<sup>2+</sup>/CAMKK2/AMPK/AR signaling axis.…”
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19182
Image 1_Immunomodulatory effects of probiotic Lactobacillus brevis ZG2488 on SARS-CoV-2 vaccine responses in mice.tif
Published 2025“…Immune responses were evaluated by measuring SARS-CoV-2-specific IgG in bronchoalveolar lavage fluid (BALF), IFN-γ secretion by splenocytes, and transcriptomic and CIBERSORT analyses of splenic immune cells.</p>Results<p>ZG2488 intervention significantly enhanced local mucosal humoral immunity in the respiratory tract (increased SARS-CoV-2-specific IgG in BALF) and systemic Th1 cellular immunity (increased IFN-γ secretion by splenocytes). …”
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19183
YOLOv8n structure diagram.
Published 2025“…GSConv employs a channel grouping approach, streamlining model parameters without sacrificing accuracy. Results on a specialized dataset reveal that YOLOv8n-BWG outperforms YOLOv8n by increasing the mean Average Precision (mAP) by 4.2%, boosting recognition speed by 21.3% per second, and decreasing both the number of floating-point operations (FLOPs) by 28.9% and model size by 26.3%. …”
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19184
DataSheet_1_RETRACTED: Macrophages depletion alleviates lung injury by modulating AKT3/GXP4 following ventilator associated pneumonia.docx
Published 2024“…Depletion of macrophages protected against lung epithelial cells and significantly decreased MMP9, MMP19, FTH, and FTL expression levels and increased GPX4 expression levels, while partially reversing the changes in macrophage. …”
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19185
Image 1_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin...
Published 2025“…In vitro experiments validated CA9 as a promising therapeutic target, with its knockdown significantly inhibiting OSCC cell proliferation and migration.…”
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19186
Table 1_Spontaneous neural activity alterations in medication-naïve primary blepharospasm: a resting-state functional magnetic resonance imaging study.docx
Published 2025“…Partial correlation analyses between the altered ALFF values and clinical variables (illness duration and Jankovic Rating Scale score) in patients with BSP were further conducted.</p>Results<p>Compared to healthy controls, medication-naïve patients with BSP exhibited significantly increased ALFF in the bilateral putamen and left premotor cortex and decreased ALFF in the bilateral thalamus (p < 0.05, threshold-free cluster enhancement with family-wise error correction for multiple comparisons). …”
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19187
Table 1_Socioeconomic status and motor coordination function among children with autism.docx
Published 2025“…We included 165 autistic children aged 2–12 years in the final analysis, among whom 88 were classified as probable DCD.</p>Results<p>After adjusting for covariates, the odds ratios for probable DCD among autistic children whose per capital family income was below 5000 yuan (OR: 4.77, 95% CI: 1.71-13.30) or 5000–8000 yuan (OR: 3.62, 95% CI: 1.36-9.61) per month were significantly higher than children whose per capital family income above 8000 yuan per month. …”
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19188
Data Sheet 11_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf
Published 2025“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
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19189
Geometric model of the binocular system.
Published 2025“…GSConv employs a channel grouping approach, streamlining model parameters without sacrificing accuracy. Results on a specialized dataset reveal that YOLOv8n-BWG outperforms YOLOv8n by increasing the mean Average Precision (mAP) by 4.2%, boosting recognition speed by 21.3% per second, and decreasing both the number of floating-point operations (FLOPs) by 28.9% and model size by 26.3%. …”
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19190
Enhanced dataset sample images.
Published 2025“…GSConv employs a channel grouping approach, streamlining model parameters without sacrificing accuracy. Results on a specialized dataset reveal that YOLOv8n-BWG outperforms YOLOv8n by increasing the mean Average Precision (mAP) by 4.2%, boosting recognition speed by 21.3% per second, and decreasing both the number of floating-point operations (FLOPs) by 28.9% and model size by 26.3%. …”
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19191
Data Sheet 1_Brackish water irrigation boosts honeysuckle (Lonicera japonica Thunb.)-salt tolerance by regulating sodium partitioning and potassium homeostasis: implications for co...
Published 2025“…The effects of these irrigation treatments on ion dynamics within the soil-plant system and the salt tolerance of honeysuckle were analyzed.</p>Results<p>With increasing brackish water irrigation, (1) significantly reduced cation accumulation in the topsoil. …”
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19192
This is raw data of IL-1β ELISA.
Published 2025“…Western-blotting was applied to evaluate the NF-κB signaling pathway.</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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19193
This is raw data of IL-10 real-time PCR.
Published 2025“…Western-blotting was applied to evaluate the NF-κB signaling pathway.</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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19194
This is raw data of Gal-9 real-time PCR.
Published 2025“…Western-blotting was applied to evaluate the NF-κB signaling pathway.</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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19195
This is raw data of IL-10 ELISA.
Published 2025“…Western-blotting was applied to evaluate the NF-κB signaling pathway.</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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19196
This is raw data of NF-κB real-time PCR.
Published 2025“…Western-blotting was applied to evaluate the NF-κB signaling pathway.</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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19197
Image1_Comprehensive analysis of Hibisci mutabilis Folium extract’s mechanisms in alleviating UV-induced skin photoaging through enhanced network pharmacology and experimental vali...
Published 2024“…In vitro experiments showed that EHMF significantly reduced UV-induced inflammatory factors in HaCaT cells and improved cell survival rates. …”
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19198
Data Sheet 1_A multimodal approach for establishing ACTL6A and ERCC1 as chemoresistance genes in locally advanced head and neck cancer.docx
Published 2025“…The median expressions of ERCC1 were significantly increased (p < 0.001) after 50% (0.19) and 100% CRT (0.23) compared to the baseline value (0.14), whereas ACTL6A expression decreased from 4.77 to 3.87 after 50% CRT (p < 0.05) and increased to 5.43 after 100% CRT. …”
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19199
This is raw data of IL-1β real-time PCR.
Published 2025“…Western-blotting was applied to evaluate the NF-κB signaling pathway.</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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19200
This is raw data of β-catenin real-time PCR.
Published 2025“…Western-blotting was applied to evaluate the NF-κB signaling pathway.</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”