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significant results » significant reductions (Expand Search), significant reduction (Expand Search)
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19201
Details of the primers applied in real-time PCR.
Published 2025“…Western-blotting was applied to evaluate the NF-κB signaling pathway.</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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19202
Image2_Comprehensive analysis of Hibisci mutabilis Folium extract’s mechanisms in alleviating UV-induced skin photoaging through enhanced network pharmacology and experimental vali...
Published 2024“…In vitro experiments showed that EHMF significantly reduced UV-induced inflammatory factors in HaCaT cells and improved cell survival rates. …”
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19203
DataSheet1_Comprehensive analysis of Hibisci mutabilis Folium extract’s mechanisms in alleviating UV-induced skin photoaging through enhanced network pharmacology and experimental...
Published 2024“…In vitro experiments showed that EHMF significantly reduced UV-induced inflammatory factors in HaCaT cells and improved cell survival rates. …”
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19204
This is raw data of viability data.
Published 2025“…Western-blotting was applied to evaluate the NF-κB signaling pathway.</p><p>Results</p><p>The proliferation of U937 cells reduced significantly in the presence of IFN-β, while it did not show a remarkable change following treatment with Vit D. …”
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19205
Rht1 functions in cell cycle progression and modulates fluconazole susceptibility.
Published 2025“…Log rank (Mantel-Cox) test assessed significant difference between wild type and <i><i>rht1</i></i>Δ/Δ. …”
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19206
Attention reduces decision uncertainty under high cognitive demand.
Published 2025“…(L) Fraction of glomeruli with significant changes with cued-odor. Yellow: increased, dark grey: decreased, light grey: unchanged. …”
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19207
Genetic interaction between <i>Zrf1</i> and RISC components regulates ISC proliferation during midgut damage.
Published 2025“…</b> Box plots show median, quartiles, and range. Statistical significance determined by Student’s t-test; ns = not significant, **p < 0.01, ****p < 0.0001.…”
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19208
Figure 5 from Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma
Published 2025“…<b>A,</b> Inhibition of PDX-CDS #4-C tumor growth after treatments with trabectedin and/or NVP-BEZ235. Significant reduction in tumor growth was observed after single treatments (*, <i>P</i> < 0.05, Student <i>t</i> test) but the inhibition increased after combination of the two drugs (significance was at least ***, <i>P</i> < 0.001, Student <i>t</i> test starting from day 23) or to single treatments (*, <i>P</i> < 0.05). …”
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19209
Relationship of different levels of physical activity on the health status of long-term breast cancer survivors: a cross-sectional study
Published 2025“…This inactivity is significantly correlated with greater physical and emotional deterioration.…”
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19210
Data Sheet 1_Variation and spread of resistomes in swine manure, manure slurries, and long-term manure-fertilized soils.docx
Published 2025“…Chromium concentrations, bacterial communities and MGEs were significantly associated with ARG profiles. Long-term slurry application resulted in elevated antibiotic, metal, and ARG concentrations in soils, with concomitant increases in high-risk ARGs and health risks.…”
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19211
Flow Chart of the Study Steps.
Published 2025“…The data were analyzed using descriptive tests (mean, standard deviation, and percentage) and analytical tests (including ANCOVA and Student T-test).</p><p>Results</p><p>The IP-GBL intervention significantly improved students’ self-efficacy in the intervention group compared to the control group (F = 26.51, df = 1.57, p-value = 0.0001, Partial Eta Squared = 0.31). …”
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19212
Image 2_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif
Published 2025“…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …”
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19213
Image 1_Mitochondrial DNA oxidation and content in different metabolic phenotypes of women with polycystic ovary syndrome.jpeg
Published 2025“…Relative mitochondrial DNA (mtDNA) content and its oxidation level (8-oxoguanine, 8-OxoG) were determined in peripheral blood leukocytes by the SYBR Green method real-time PCR.</p>Results<p>Our findings showed that patients with PCOS had decreased mtDNA content and increased oxidation damage. …”
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19214
Data Sheet 1_Pregnancy hormones increase cardiac capillary density via the PGC-1α/ERRα/VEGF pathway in cardiomyocytes.docx
Published 2025“…</p>Methods<p>We analyzed cell proliferation, capillary density, hypertrophy, and gene expression using immunostaining and quantitative RT-PCR to evaluate differential gene expression in mouse hearts at different stages during pregnancy and after treatment with combinations of progesterone and estrogen for up to 14 days. </p>Results<p>We found that the number of proliferating cells in the hearts of pregnant mice began to increase at gestational day 3 (GD3), peaked at GD14—mainly in fibroblasts and endothelial cells (ECs), but not in cardiomyocytes (CMs)—and decreased immediately after delivery. …”
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19215
Data Sheet 1_STING regulates NETs formation by activating GSDMD in influenza viral pneumonia.pdf
Published 2025“…Symptoms of pneumonia in STING-KO mice infected with PR8 were significantly milder than those in WT mice, and NETs were less likely to form in the lung tissue of STING-KO mice. …”
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19216
Table 3_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx
Published 2025“…Furthermore, the associations among them were analyzed.</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. …”
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19217
Integrating legumes into cropping systems enhances soil carbon and nitrogen content while reduces the soil carbon-to-nitrogen ratio: A global meta-analysis
Published 2025“…Moreover, SOC and STN increased when legumes replaced fallow or gramineous soil, whereas SCN significantly decreased only when legumes replaced gramineous systems. …”
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19218
Image 2_CT angiography-derived three-dimensional pulmonary vein topography is related to the outcome after cryoballoon ablation.tiff
Published 2025“…The number of occlusion attempts in the right inferior PV was significantly higher in the PVI failure group indicating a technical more complex balloon occlusion. …”
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19219
DataSheet1_Formulation development, characterization, and evaluation of sorafenib-loaded PLGA–chitosan nanoparticles.docx
Published 2024“…The pharmacokinetic parameters were improved significantly when the results were compared with commercially available sorafenib formulations.…”
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19220
Supplementary file 1_The efficacy of resveratrol in the treatment of liver fibrosis: a systematic review and meta-analysis of preclinical studies.docx
Published 2025“…It significantly inhibited the accumulation of extracellular matrix components and modulated profibrotic mediators. …”