Data Sheet 3_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.pdf by Miguel Ângelo-Dias (20936444)

“…We evaluated 74 lymphocyte subsets, including follicular and non-follicular CD4 and CD8 T cells, and functional markers CD69 and PD-L1, under basal and stimulated conditions.</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …”

<b>Metabolic Improvements with Tirzepatide in Lipodystrophy: A Novel Option?</b> by Rasimcan Meral (5022425)

“…These disorders are defined by abnormal fat distribution, with near-total (generalized lipodystrophy, GL) or partial (partial lipodystrophy, PL; e.g. familial partial lipodystrophy, FPLD) absence of adipocyte mass leading to a decreased ability to store lipids safely. Excess lipids are more likely to be stored in non-adipose tissues, which leads to the metabolic manifestations. …”

Table 9_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.xlsx by Ying Dong (41989)

“…MR analysis was then performed using summary statistics from the EBI database (n = 484,598) to assess the putative relationships between candidate genes and psoriasis risk.</p>Results<p>Seven genetically informed candidate genes were identified as being significantly associated with psoriasis susceptibility. …”

Table 1_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.xlsx by Miguel Ângelo-Dias (20936444)

“…We evaluated 74 lymphocyte subsets, including follicular and non-follicular CD4 and CD8 T cells, and functional markers CD69 and PD-L1, under basal and stimulated conditions.</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …”

Image 1_Natural killer cell as a potential predictive biomarker for early immune checkpoint inhibitor-associated cardiovascular adverse events: a retrospective cohort study.tif by Yujuan Wu (2249857)

“…Propensity score matching (PSM) was used to validate the predictive value of baseline NK cell proportion for CAVEs.</p>Results<p>ScRNA-seq data revealed decreased CD8+ T and B cell proportions in the CVAEs group, while NK cell proportions increased. …”

DataSheet1_Coptisine enhances the sensitivity of chemoresistant breast cancer cells by inhibiting the function and expression of ABC transporters.PDF by Safaa Yehia Eid (17768736)

“…In MCF-7/ADR and MDA-MB-231/ADR cells, COP (31 μM) enhanced DOX cytotoxicity with CI (0.77 and 0.75), RR (2.58 and 3.33), and IB suggesting synergism. COP significantly inhibits ABCT function in resistant BC cell lines, increases Rho123 accumulation, and decreases efflux more than VER; 2.1 and 1.2-fold, respectively. …”

Table 3_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.xlsx by Yan Fan (575147)

“…This secretion was reinforced by the above sera. IGFBP5 decreased in ALI mice’s blood, while its supplement exacerbated inflammation. …”

Table 1_Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammatory cel... by Jingjian Dong (12458730)

“…Meanwhile, exosomes were extracted from MH7A cells and loaded with PSPA, then co-incubated with inflammatory cells to observe the targeting capability of the drug-loaded exosomes.</p>Results<p>PSPA significantly reduced joint swelling and structural damage in CIA rats, with the highest dose (40 mg/kg) reducing tissue hyperplasia and inflammatory infiltration. …”

Table 3_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.doc by Md Shoykot Jahan (22776341)

“…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. This resulted in decreased production of inflammatory mediators (TNF-α, IL-6, IL-1β), reduced iNOS and ROS levels, and impaired bacterial clearance.…”

Image 1_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif by Ying Dong (41989)

“…MR analysis was then performed using summary statistics from the EBI database (n = 484,598) to assess the putative relationships between candidate genes and psoriasis risk.</p>Results<p>Seven genetically informed candidate genes were identified as being significantly associated with psoriasis susceptibility. …”

Image 5_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.tif by Ying Dong (41989)

“…MR analysis was then performed using summary statistics from the EBI database (n = 484,598) to assess the putative relationships between candidate genes and psoriasis risk.</p>Results<p>Seven genetically informed candidate genes were identified as being significantly associated with psoriasis susceptibility. …”

Table 3_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.xlsx by Ying Dong (41989)

“…MR analysis was then performed using summary statistics from the EBI database (n = 484,598) to assess the putative relationships between candidate genes and psoriasis risk.</p>Results<p>Seven genetically informed candidate genes were identified as being significantly associated with psoriasis susceptibility. …”

Image 2_Natural killer cell as a potential predictive biomarker for early immune checkpoint inhibitor-associated cardiovascular adverse events: a retrospective cohort study.tif by Yujuan Wu (2249857)

“…Propensity score matching (PSM) was used to validate the predictive value of baseline NK cell proportion for CAVEs.</p>Results<p>ScRNA-seq data revealed decreased CD8+ T and B cell proportions in the CVAEs group, while NK cell proportions increased. …”

Table 7_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.xlsx by Miguel Ângelo-Dias (20936444)

“…We evaluated 74 lymphocyte subsets, including follicular and non-follicular CD4 and CD8 T cells, and functional markers CD69 and PD-L1, under basal and stimulated conditions.</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …”

Table 1_Communal and agentic teacher behavior in teacher-child dyads. A new self-report scale based on a circumplex approach.docx by Madeleine Kreutzmann (20296713)

“…Teacher interpersonal behavior correlated significantly with perceived relationship quality and emotions: high relationship quality and positive emotions were associated with high communion and low agency, whereas low relationship quality and negative emotions were associated with low communion and high agency, supporting construct validity. …”

Image 2_Microglial adenosine A2A receptor in the paraventricular thalamic nucleus regulates pain sensation and analgesic effects independent of opioid and cannabinoid receptors.tif by Yiping Cao (1229856)

“…Pharmacological activation of local PVT A_2AR with its agonist CGS21680 induced significantly decreased 50% paw withdrawal threshold (50%PWTs) and paw withdrawal latency (PWLs), as measured by the Von Frey test and Hargreaves test in adult mice. …”

Data Sheet 5_Beyond salt tolerance: SOS1-13’s pivotal role in regulating the immune response to Fusarium oxysporum in Solanum phureja.docx by Liqin Liang (652560)

“…Conversely, silencing the ortholog gene NbSOS1-13 in Nicotiana benthamiana showed more accumulation of ROS, serious cell necrosis, reduced activities of SOD and CAT, significantly increased MDA level, obvious leaf wilting, decreased tolerance to infection, and reduced leaf stomatal closure rate and accelerated stomatal area. …”

Data Sheet 3_Identification of novel gut microbiota-related biomarkers in cerebral hemorrhagic stroke.zip by Fengli Ye (22123540)

“…Machine learning identified four hub genes—LEF1, ITGAX, BLVRB, and ATF4. All were significantly upregulated in ICH tissues and plasma, correlating with immune cell infiltration. …”

Image 2_Inhibition of CRM1 reverses hypoxia-driven chemoresistance in acute myeloid leukemia via overcoming HIF-1α-mediated lysosomal sequestration.jpeg by Xiaohui Feng (2869535)

“…Combination treatment with Selinexor and DNR significantly increased apoptosis and DNA damage in vitro and reduced leukemia burden in zebrafish xenografts.…”

Table 2_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.xlsx by Miguel Ângelo-Dias (20936444)

“…We evaluated 74 lymphocyte subsets, including follicular and non-follicular CD4 and CD8 T cells, and functional markers CD69 and PD-L1, under basal and stimulated conditions.</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …”