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13961
Table 5_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.xlsx
Published 2025“…Brain network metabolic connectivity was assessed using Permutation_IHEP software and visualized with BrainNet Viewer. Our results indicate that SUVRs in most brain regions were decreased in patients with hypertension or T2DM but increased in patients with obesity or gout. …”
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13962
Table 6_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co...
Published 2025“…Subgroup analyses were performed based on factors such as disease stage, pathological type, etc.</p>Results<p>After screening, 19 phase 3 RCTs involving 9335 patients were included. …”
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13963
Image 3_Prediction of major adverse cardiovascular events following ST-segment elevation myocardial infarction using cardiac obesity marker—epicardial adipose tissue mass index: a...
Published 2025“…Background<p>Although reperfusion therapy has led to improvements in the acute phase of ST-segment elevation myocardial infarction (STEMI), the incidence of major adverse cardiovascular events (MACE) following STEMI has not significantly decreased. The accumulation of epicardial adipose tissue (EAT) may be associated with poorer STEMI prognosis and could serve as a potential prognostic marker. …”
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13964
Table 1_Pingwei Powder alleviates high-fat diet-induced colonic inflammation by modulating microbial metabolites SCFAs.xlsx
Published 2025“…Experimental validation showed that PWP significantly downregulated the levels of PI3K, pAKT/AKT, and pmTOR/mTOR in colonic tissue, thereby enhancing autophagy in colonic epithelial cells, as evidenced by decreased levels of P62 and increased LC3B-II/LC3B-I ratios. …”
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13965
Table 3_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co...
Published 2025“…Subgroup analyses were performed based on factors such as disease stage, pathological type, etc.</p>Results<p>After screening, 19 phase 3 RCTs involving 9335 patients were included. …”
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13966
Data Sheet 1_Profile and risk factors of blood donors who experienced adverse reactions: a cross-sectional study on donor hemovigilance data reported to the national network from 2...
Published 2025“…Lastly, risk factors for blood donation-related syncope were explored.</p>Results<p>Between 2020 and 2022, 32,523 cases of ADRs were reported, among which VVRs accounted for 96.8% of all reactions. …”
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13967
Data Sheet 3_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway....
Published 2025“…Immunofluorescence and Western blotting (WB) were conducted to examine apoptosis-related protein expression.</p>Results<p>Polygonatum sibiricum polysaccharides significantly improved zebrafish swimming behavior, reduced blood glucose and fructosamine levels, and enhanced ATP production (p < 0.01). …”
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13968
Image 6_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co...
Published 2025“…Subgroup analyses were performed based on factors such as disease stage, pathological type, etc.</p>Results<p>After screening, 19 phase 3 RCTs involving 9335 patients were included. …”
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13969
Table 7_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx
Published 2025“…Immunofluorescence and Western blotting (WB) were conducted to examine apoptosis-related protein expression.</p>Results<p>Polygonatum sibiricum polysaccharides significantly improved zebrafish swimming behavior, reduced blood glucose and fructosamine levels, and enhanced ATP production (p < 0.01). …”
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13970
Image 3_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co...
Published 2025“…Subgroup analyses were performed based on factors such as disease stage, pathological type, etc.</p>Results<p>After screening, 19 phase 3 RCTs involving 9335 patients were included. …”
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13971
Table 4_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.xlsx
Published 2025“…However, the pandemic significantly slowed the decline in low- and low-middle SDI regions.…”
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13972
Image 3_Prevention of chemotherapy drug-mediated human hair follicle damage: combined use of cooling with antioxidant suppresses oxidative stress and prevents matrix keratinocyte c...
Published 2025“…The effects of a panel of antioxidants in combination with cooling were assessed.</p>Results<p>Chemotherapy agents reduced keratinocyte viability at 37°C by ∼65%–70%, induced HF dystrophy evident by decreased proliferation (9% Ki-67+ cells), increased apoptosis (23% TUNEL+ cells), and reduced anagen (∼10%) and pigmentation. …”
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13973
Image_1_Unraveling the key mechanisms of Gastrodia elata continuous cropping obstacles: soil bacteria Massilia, Burkholderia-Caballeronia-Paraburkholderia, and Dyella along with so...
Published 2024“…Soil sample collected from the uncultivated field was used as the control (CK).</p>Results<p>Metabarcoding sequencing showed high bacterial alpha diversity during the cultivation of Tian-ma (0 Year) and the period of deterioration of soil bacterial community. (1 Year), with decreased anaerobic bacterial abundance and increased copiotrophic bacterial abundance. …”
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13974
De-repression of endogenous retroelements triggers viral mimicry, interferon, and cytokine response.
Published 2025“…<p><b>(A)</b> Volcano plot of ATAC-seq results for sequence repeats with increased (blue) and decreased (red) chromatin accessibility in ATRX-null microglia. …”
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13975
<b>Soil C mineralization and C-Fe coupling: a trade-off between Fenton reaction and </b><b>microbial activity</b><b> under straw mulching in banana orchards</b>
Published 2025“…Although straw mulching negatively impacted soil C mineralization via reducing ROS, it also promoted soil C mineralization through enhancing microbial activity and decreasing Fe-OC, resulting in significantly increased soil C mineralization. …”
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13976
Knockdown of fatty acid binding protein 3 attenuates cerebral Ischemia-reperfusion injury <i>via</i> inhibiting neuronal apoptosis in mice
Published 2025“…Western blot analysis was performed to evaluate the expression of apoptosis-related proteins. Results: FABP3 expression was significantly upregulated following cerebral I/R injury. …”
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13977
Table1_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.docx
Published 2024“…Whole blood ELISpot assays were conducted to quantify TNF expression [stimulated by lipopolysaccharide (LPS)] and IFNγ expression (stimulated by anti-CD3/CD28 mAb), which were then used for assignment to one of four subgroups including an ‘immunocompetent’, ‘immunosuppressed endotype’, and two ‘mixed’ endotypes.</p>Results<p>Whole blood TNF spot-forming units were significantly increased in septic and CINS patients on days 4 and 7 compared to healthy subjects. …”
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13978
Data Sheet 1_Listening to mom in the neonatal intensive care unit: a randomized trial of increased maternal speech exposure on white matter connectivity in infants born preterm.pdf
Published 2025“…</p>Results<p>Groups were equivalent on medical and demographic variables. …”
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13979
Image2_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.jpeg
Published 2024“…Whole blood ELISpot assays were conducted to quantify TNF expression [stimulated by lipopolysaccharide (LPS)] and IFNγ expression (stimulated by anti-CD3/CD28 mAb), which were then used for assignment to one of four subgroups including an ‘immunocompetent’, ‘immunosuppressed endotype’, and two ‘mixed’ endotypes.</p>Results<p>Whole blood TNF spot-forming units were significantly increased in septic and CINS patients on days 4 and 7 compared to healthy subjects. …”
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13980
Image3_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.jpeg
Published 2024“…Whole blood ELISpot assays were conducted to quantify TNF expression [stimulated by lipopolysaccharide (LPS)] and IFNγ expression (stimulated by anti-CD3/CD28 mAb), which were then used for assignment to one of four subgroups including an ‘immunocompetent’, ‘immunosuppressed endotype’, and two ‘mixed’ endotypes.</p>Results<p>Whole blood TNF spot-forming units were significantly increased in septic and CINS patients on days 4 and 7 compared to healthy subjects. …”