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significant risk » significant role (Expand Search)
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2301
Factor associated with neonatal mortality.
Published 2025“…</p><p>Conclusion</p><p>Administering a minimum of one maternal tetanus dose significantly lowers the risk of neonatal mortality. …”
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2302
Data Sheet 1_Pregnancy and contraceptive use among participants of childbearing potential in the HVTN 705 HIV vaccine trial in Southern Africa.docx
Published 2025“…Oral contraception was associated with the least reduction in pregnancy risk; implants were associated with the most reduction in pregnancy risk (p < 0.001).…”
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2303
Data Sheet 1_N6-methyladenosine RNA landscape in the aged mouse hearts.zip
Published 2025“…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H<sub>2</sub>O<sub>2</sub>-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …”
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2304
Data Sheet 2_N6-methyladenosine RNA landscape in the aged mouse hearts.zip
Published 2025“…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H<sub>2</sub>O<sub>2</sub>-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …”
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2305
Data Sheet 3_N6-methyladenosine RNA landscape in the aged mouse hearts.zip
Published 2025“…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H<sub>2</sub>O<sub>2</sub>-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …”
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2306
Data Sheet 4_N6-methyladenosine RNA landscape in the aged mouse hearts.pdf
Published 2025“…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H<sub>2</sub>O<sub>2</sub>-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …”
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2307
Table 2_Epidemiology of second trimester induced abortion in Ethiopia: a systematic review and meta-analysis.docx
Published 2025“…These abortions are particularly concerning due to the heightened risk of complications and maternal mortality. In Ethiopia, there is a lack of nationally representative data regarding the magnitude and associated factors of second-trimester induced abortions. …”
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2308
Data Sheet 1_Effects of sodium tanshinone IIA sulfonate injection on pro-inflammatory cytokines, adhesion molecules and chemokines in Chinese patients with atherosclerosis and athe...
Published 2025“…</p>Conclusion<p>The use of STS in patients with AS and ASCVD appeared to significantly decrease levels of pro-inflammatory cytokines, adhesion molecules, and chemokines.…”
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2309
Table 1_Epidemiology of second trimester induced abortion in Ethiopia: a systematic review and meta-analysis.docx
Published 2025“…These abortions are particularly concerning due to the heightened risk of complications and maternal mortality. In Ethiopia, there is a lack of nationally representative data regarding the magnitude and associated factors of second-trimester induced abortions. …”
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2310
Data Sheet 1_Effect of acupuncture on cognitive impairment induced by sleep deprivation in animal models: a preclinical systematic review and meta-analysis.docx
Published 2025“…Secondary outcomes focused on molecular markers such as brain-derived neurotrophic factor (BDNF), tropomyosin receptor kinase B (TrkB), and indicators of oxidative stress. The risk of bias was evaluated using the SYRCLE tool, and data were analyzed using R software. …”
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2311
Table 2_Associations between physical fitness components and metabolic syndrome in middle-aged adults: a cross-sectional study using relative strength indicators and ROC analysis.d...
Published 2025“…Introduction<p>Metabolic syndrome (MetS) is a major risk factor for cardiovascular disease (CVD) and type 2 diabetes, particularly in middle-aged populations. …”
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2312
Image 2_Effect of acupuncture on cognitive impairment induced by sleep deprivation in animal models: a preclinical systematic review and meta-analysis.tif
Published 2025“…Secondary outcomes focused on molecular markers such as brain-derived neurotrophic factor (BDNF), tropomyosin receptor kinase B (TrkB), and indicators of oxidative stress. The risk of bias was evaluated using the SYRCLE tool, and data were analyzed using R software. …”
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2313
Supplementary file 1_The efficacy and safety of Fuzheng traditional Chinese medicine injections in the treatment of acute ischemic stroke: a systematic review and network meta-anal...
Published 2025“…The quality of the included RCTs was assessed using the risk-of-bias 2 (RoB2) tool. NMA in the frequentist framework was designed to access the efficacy of different Fuzheng TCMIs.…”
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2314
Table 1_Associations between physical fitness components and metabolic syndrome in middle-aged adults: a cross-sectional study using relative strength indicators and ROC analysis.d...
Published 2025“…Introduction<p>Metabolic syndrome (MetS) is a major risk factor for cardiovascular disease (CVD) and type 2 diabetes, particularly in middle-aged populations. …”
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2315
DataSheet1_Characteristics of adverse reactions of three anti-glioma drugs in WHO-VigiAccess.ZIP
Published 2024“…This study aims to determine which anti-glioma medication presents the lowest risk for personalized use in clinical patients by assessing the adverse drug reactions (ADRs) associated with these medications as reported in the World Health Organization (WHO) VigiAcess database, and by comparing the characteristics of adverse responses among the three drugs.…”
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2316
Image 1_Effect of acupuncture on cognitive impairment induced by sleep deprivation in animal models: a preclinical systematic review and meta-analysis.tif
Published 2025“…Secondary outcomes focused on molecular markers such as brain-derived neurotrophic factor (BDNF), tropomyosin receptor kinase B (TrkB), and indicators of oxidative stress. The risk of bias was evaluated using the SYRCLE tool, and data were analyzed using R software. …”
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2317
SEAwise report on effects of spatial management measures suggested in SEAwise to safeguard species, habitats and choke species on fisheries selectivity and fuel cost
Published 2024“…Under the FMSY scenario, the fuel consumption for all the fleets decreased significantly due to the decrease in fishing effort. …”
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2318
Table 1_Manure substitution for chemical nitrogen enhances soil quality without compromising maize yield: a short-term field experiment in Northeast China.xlsx
Published 2025“…Introduction<p>Manure substitution for chemical nitrogen has the potential to enhance crop yield, improve soil quality, and reduce environmental risks. Soil microorganisms perform critical functions in mediating soil nutrient cycling after the organic manure application. …”
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2319
Effect of regional nerve block on tourniquet-related injury in pediatric patients undergoing lower limb surgery: a randomized controlled study
Published 2025“…Additionally, patients in the PNB group had a significantly shorter time to first ambulation and a shorter hospital length of stay.…”
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2320
Data Sheet 1_The impact of small food workshops management regulations on aflatoxin B1 in home-made peanut oil and the liver function of high-consumption area residents: an interru...
Published 2024“…The implementation of SFWMR was associated with a significant reduction in AFB<sub>1</sub> concentrations in HMPO, showing an immediate decrease of 2.865 μg/kg (P = 0.006) and a sustained annual reduction of 2.593 μg/kg (P = 0.034). …”