يعرض 21,021 - 21,040 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant risks decrease ))', وقت الاستعلام: 0.50s تنقيح النتائج
  1. 21021

    Image 1_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png حسب Feifei Yang (334047)

    منشور في 2025
    "…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …"
  2. 21022

    Association of Patient Cost-Sharing with Adherence to GLP-1a and Adverse Health Outcomes حسب Donglan Zhang (702608)

    منشور في 2025
    "…Results Among 61,907 adults initiated GLP-1a, higher 30-day OOP costs were associated with decreased adherence. Patients in the highest OOP cost quartile (Q4: $80–$3,375) had significantly higher odds of non-adherence (OR: 1.25; 95% CI: 1.19–1.31) compared to those in the lowest quartile (Q1: $0–$21). …"
  3. 21023

    DataSheet1_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf حسب Jianan Zhang (786459)

    منشور في 2025
    "…Up-regulation of DYNLT3 expression significantly inhibited tumor growth in a nude mouse model, while downregulation of DYNLT3 showed the opposite results. …"
  4. 21024

    Data from: Quantifying seed rain patterns in a remnant and a chronosequence of restored tallgrass prairies in north central Missouri حسب Katherine Wynne (22078346)

    منشور في 2025
    "…We further found that decreases in seed rain quantity across the chronosequence did not correspond with increases in seed mass, suggesting a lack of tradeoffs between these metrics. …"
  5. 21025

    Image 1_Integrated analysis of miRNAs-mRNAs in skeletal muscle development revealed that novel-miR-766 affects myoblast differentiation and myofiber-type formation in sheep.tif حسب Zhenzhen Gu (21488168)

    منشور في 2025
    "…In vitro assays revealed that myoblast differentiation and myotube formation were significantly inhibited by MYH3 knockdown via siMYH3 and that novel-miR-766 targets and decreases the expression of MYH3. …"
  6. 21026

    Image 1_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tif حسب Priscila Silva (556743)

    منشور في 2025
    "…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …"
  7. 21027

    Image 5_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png حسب Feifei Yang (334047)

    منشور في 2025
    "…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …"
  8. 21028

    Data Sheet 1_Molecular insights into Atorvastatin’s role in delaying intervertebral disc degeneration.zip حسب Yupeng Li (507508)

    منشور في 2025
    "…</p>Results<p>Pretreatment with 10 μM atorvastatin significantly improved the survival rate of NPCs exposed to hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) and reduced apoptosis. …"
  9. 21029

    Image 1_Fraxin modulates lipid metabolism as well as gut flora to avert NAFLD.tif حسب Yang Jing (2231179)

    منشور في 2025
    "…GO and KEGG analyses suggested that fraxin primarily treats NAFLD by modulating lipid metabolism and atherosclerosis-related signaling pathways. In vivo, fraxin significantly lowered liver index and visceral fat accumulation, reduced serum levels of “interleukin-6 (IL-6),” “aspartate aminotransferase,” “tumor necrosis factor-α (TNF-α)” and “alanine aminotransferase,” and decreased hepatic TG content. …"
  10. 21030

    Table 1_Seeds of success: seed biology and germination response of Gazania weed in Australia.xlsx حسب Muhammad Adnan (678952)

    منشور في 2025
    "…Seedling emergence and root length decreased with increasing burial depth and no emergence was observed at 6 cm depth. …"
  11. 21031

    Figure 5 from Gut Microbiome Profiling in Eμ-TCL1 Mice Reveals Intestinal Changes and a Dysbiotic Signature Specific to Chronic Lymphocytic Leukemia حسب Sydney A. Skupa (18597728)

    منشور في 2025
    "…Asterisks denote the significance between leukemic mice over time (***, <i>P</i> < 0.001). …"
  12. 21032

    Effects of extracts on body weight. حسب Srabonti Saha (17452756)

    منشور في 2025
    "…The results demonstrated that higher doses (200 mg) of <i>C. chinense</i> methanol extract inhibited immune responses, whereas lower doses helped restore them. The extracts significantly decreased pro-inflammatory mediators and cytokines in LPS-activated macrophages. …"
  13. 21033

    Data Sheet 1_Global burden of nasopharyngeal carcinoma attributable to alcohol use: a 1990–2021 analysis with projections to 2040.pdf حسب Zhenyi Lu (22004786)

    منشور في 2025
    "…</p>Results<p>From 1990 to 2021, global ASMR declined from 0.31 to 0.19 per 100,000 population (AAPC −1.66; 95% CI −1.79 to −1.52) and ASDR fell with an AAPC of −1.72 (95% CI −1.87 to −1.57). Male ASMR decreased from 0.42 to 0.27 per 100,000 (AAPC −1.60), and female ASMR from 0.21 to 0.12 per 100,000 (AAPC −2.25). …"
  14. 21034

    Table 2_Integrated analysis of miRNAs-mRNAs in skeletal muscle development revealed that novel-miR-766 affects myoblast differentiation and myofiber-type formation in sheep.xlsx حسب Zhenzhen Gu (21488168)

    منشور في 2025
    "…In vitro assays revealed that myoblast differentiation and myotube formation were significantly inhibited by MYH3 knockdown via siMYH3 and that novel-miR-766 targets and decreases the expression of MYH3. …"
  15. 21035

    Chromatin accessibility profiling of Treg cells in acute urticaria حسب Leilei Wen (3551444)

    منشور في 2025
    "…In this study, we found that the frequency of Tregs in peripheral blood mononuclear cells (PBMCs) was decreased in patients with acute urticaria compared with normal controls by flow cytometry. …"
  16. 21036

    Table 2_SRC is a potential target of Arctigenin in treating triple-negative breast cancer: based on machine learning algorithms, molecular modeling and in Vitro test.xlsx حسب Yuezhou Huang (9998177)

    منشور في 2025
    "…Western blotting indicated that AG significantly reduced the levels of Bcl-2, caspase-3, and caspase-9, as well as decreased SRC, p-PI3K-p85, p-AKT1, p-MEK1/2, and p-ERK1/2 expression in TNBC cells in a concentration dependent manner.…"
  17. 21037

    Table 3_SRC is a potential target of Arctigenin in treating triple-negative breast cancer: based on machine learning algorithms, molecular modeling and in Vitro test.docx حسب Yuezhou Huang (9998177)

    منشور في 2025
    "…Western blotting indicated that AG significantly reduced the levels of Bcl-2, caspase-3, and caspase-9, as well as decreased SRC, p-PI3K-p85, p-AKT1, p-MEK1/2, and p-ERK1/2 expression in TNBC cells in a concentration dependent manner.…"
  18. 21038

    Image 2_The alteration of the sensorimotor network in trigeminal neuralgia after microvascular decompression surgery: a follow-up study using independent component analysis.tif حسب Yan Zhang (8098)

    منشور في 2025
    "…</p>Results<p>Compared to the HC, increased activity was observed in the right frontal operculum cortex, right insular cortex, right inferior frontal gyrus (pars opercularis), and right frontal pole in TN patients. Conversely, decreased activity was found in the right cerebellum (lobule IX) and left cerebellum (lobules VIII and IX). …"
  19. 21039

    Table 1_Machine learning identifies neutrophil extracellular traps-related biomarkers for acute ischemic stroke diagnosis.docx حسب Haipeng Zhang (3413288)

    منشور في 2025
    "…NDEGs were significantly enriched in immune regulation and leukocyte apoptosis (GO) and NETs formation pathway (KEGG). …"
  20. 21040

    Table 1_Integrated analysis of miRNAs-mRNAs in skeletal muscle development revealed that novel-miR-766 affects myoblast differentiation and myofiber-type formation in sheep.xlsx حسب Zhenzhen Gu (21488168)

    منشور في 2025
    "…In vitro assays revealed that myoblast differentiation and myotube formation were significantly inhibited by MYH3 knockdown via siMYH3 and that novel-miR-766 targets and decreases the expression of MYH3. …"