يعرض 21,221 - 21,240 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant risks decrease ))', وقت الاستعلام: 0.48s تنقيح النتائج
  1. 21221

    Table1_CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder.DOCX حسب Cataldo Martucci (3117069)

    منشور في 2024
    "…In a murine house dust mite (HDM) model of asthma exacerbated by influenza virus A (IAV) (H3N3), CHF6297 (0.1 mg/kg, i.n.) significantly decreased airway neutrophilia compared to vehicle-treated IAV/HDM-challenged mice. …"
  2. 21222

    Image1_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif حسب Zi Yang (276531)

    منشور في 2024
    "…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …"
  3. 21223

    Table1_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.docx حسب Zi Yang (276531)

    منشور في 2024
    "…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …"
  4. 21224

    Table 2_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx حسب Olubukunmi Amos Ilori (22446976)

    منشور في 2025
    "…The miRNA cargo exhibited a similar pattern, except miR-141-3p, miR-153-3p, both increased slightly, and miR-223-3p, which increased substantially; miR-148a-3p, which decreased; and miR-33a-3p, which was no longer detectable after digestion. …"
  5. 21225

    Table 1_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls حسب Xue Li (285380)

    منشور في 2025
    "…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …"
  6. 21226

    This is raw data of IL-10 ELISA. حسب Farzad Nasri (8941850)

    منشور في 2025
    "…IFN-β in contrast to Vit D decreased <i><i>Gal-9</i></i> gene expression. <i>β-<i>catenin</i></i> gene expression increased after IFN-β or Vit D treatment. …"
  7. 21227

    Image 3_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff حسب Ayaka Goto (20858771)

    منشور في 2025
    "…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …"
  8. 21228

    Fuzzy PID control block diagram. حسب Wanjun Zhang (496858)

    منشور في 2025
    "…The results demonstrate that the self-correcting fuzzy PID control significantly optimizes key performance metrics: overshoot (reduced by 21.3%), settling time (shortened by 34.7%), and steady-rate error (decreased by 18.9%), outperforming both traditional PID and fuzzy PID methods in concentration and pH regulation. …"
  9. 21229

    Data Sheet 4_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.zip حسب Xue Li (285380)

    منشور في 2025
    "…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …"
  10. 21230

    Image 4_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf حسب Yufei Li (433737)

    منشور في 2025
    "…YQHX also restored MAMs morphology, decreased mPTP opening and Ca<sup>2+</sup> levels, and reversed GRP75 downregulation blocked by MKT-077 under oxygen-glucose deprivation.…"
  11. 21231

    This is raw data of NF-κB real-time PCR. حسب Farzad Nasri (8941850)

    منشور في 2025
    "…IFN-β in contrast to Vit D decreased <i><i>Gal-9</i></i> gene expression. <i>β-<i>catenin</i></i> gene expression increased after IFN-β or Vit D treatment. …"
  12. 21232

    Supplementary file 1_Transcriptome-wide N6-methyladenosinem modifications analysis of chicken cecum in responding to Campylobacter jejuni inoculation.zip حسب Yanan Zhao (3132906)

    منشور في 2025
    "…</p>Results<p>In the S group, the level of proinflammatory cytokines (IL-8, IL-1β, IL-18, TNF-α, IL-17A) and global RNA methylation were significantly decreased (P < 0.05). A total of 30,427 and 30,367 m<sup>6</sup>A peaks were identified in R and S groups, which were primarily located in 3'UTR and CDS regions. …"
  13. 21233

    Parameter optimal analysis. حسب Wanjun Zhang (496858)

    منشور في 2025
    "…The results demonstrate that the self-correcting fuzzy PID control significantly optimizes key performance metrics: overshoot (reduced by 21.3%), settling time (shortened by 34.7%), and steady-rate error (decreased by 18.9%), outperforming both traditional PID and fuzzy PID methods in concentration and pH regulation. …"
  14. 21234

    Data Sheet 1_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.zip حسب Xue Li (285380)

    منشور في 2025
    "…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …"
  15. 21235

    Data Sheet 1_The characteristics of auditorial event-related potential under propofol sedation associated with preoperative cognitive performance in glioma patients.docx حسب Xinxin Wang (134010)

    منشور في 2024
    "…Compared to that in the non-MCI group, the average amplitude of the MMN component evoked by the novel stimulus significantly decreased during the recovery period in the MCI group (−3.895 ± 1.961 μV vs. -1.617 ± 1.831 μV, p = 0.003). …"
  16. 21236

    Data Sheet 1_Eupalinolide A inhibits cancer progression and induces ferroptosis and apoptosis by targeting the AMPK/mTOR/SCD1 signalling in non-small cell lung cancer.docx حسب Yonghui Zhang (279832)

    منشور في 2025
    "…EA treatment (25 mg/kg) markedly inhibited tumour growth in vivo in a xenograft model; both tumour weight and tumour volume decreased by more than 60% without significantly affecting the body weight of tumour-bearing mice.…"
  17. 21237

    Image 4_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff حسب Ayaka Goto (20858771)

    منشور في 2025
    "…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …"
  18. 21238

    Data Sheet 3_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.zip حسب Xue Li (285380)

    منشور في 2025
    "…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …"
  19. 21239

    Table 3_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls حسب Xue Li (285380)

    منشور في 2025
    "…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …"
  20. 21240

    Image 2_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf حسب Yufei Li (433737)

    منشور في 2025
    "…YQHX also restored MAMs morphology, decreased mPTP opening and Ca<sup>2+</sup> levels, and reversed GRP75 downregulation blocked by MKT-077 under oxygen-glucose deprivation.…"