Data Sheet 1_Integrated computational and experimental identification of N-[(1H-1,2,4-triazol-3-yl)phenyl]-1-(1H-pyrazolo[3,4-b]pyridin-3-yl)methanamide as a potent and selective T... by Xinxin Ying (21507500)

“…Survival analysis revealed a significant correlation between elevated TIM-3 expression and decreased patient survival. …”

Table 1_Does screening mode matter? A repeated cross-sectional study of computer self-administered vs. clinician-administered screening of youth substance use in pediatric primary... by Chloe Gao (11107228)

“…Introduction<p>Universal youth substance use screening in pediatric primary care enables early detection and intervention, which, in turn, can help decrease the risk of problematic substance use. Screening mode [electronic self-administered survey (SA) vs. clinician-administered interview (CA)] may influence whether substance use is reported and, therefore, clinical decisions about whether and how to intervene.…”

Impact of Oral Semaglutide on Kidney Outcomes in People with Type 2 Diabetes: Results from the SOUL Randomized Trial by Johannes F. E. Mann (22017555)

“…</p><p dir="ltr">RESEARCH DESIGN AND METHODS</p><p dir="ltr">SOUL (NCT03914326), a randomized, double-blind trial, compared oral semaglutide vs placebo in people with T2D, ASCVD, and/or CKD, showing a 14% reduction in risk of major adverse CV events. Prespecified kidney outcomes included a 5-point composite (≥50% decrease in estimated glomerular filtration rate [eGFR], persistent eGFR <15 mL/min/1.73 m2, initiation of chronic kidney replacement therapy, or death from kidney or CV causes); a 4-point composite (excluding CV death); and eGFR decline. …”

Data Sheet 7_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Global incidence rates of pancreatitis have notably increased since 1999, while the overall burden of DALYs has decreased over the past 30 years. In the APC model, different age groups experienced varying risks. …”

Data Sheet 3_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Global incidence rates of pancreatitis have notably increased since 1999, while the overall burden of DALYs has decreased over the past 30 years. In the APC model, different age groups experienced varying risks. …”

Data Sheet 4_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Global incidence rates of pancreatitis have notably increased since 1999, while the overall burden of DALYs has decreased over the past 30 years. In the APC model, different age groups experienced varying risks. …”

Data Sheet 1_Prevalence of kidney stones based on metabolic health and weight criteria: reports from the national health and nutrition examination survey 2007-2018 data analysis.pd... by Xijie Ding (21583937)

“…Physical activity was associated with a decreased risk of kidney stones, particularly among individuals with MUO. …”

Data Sheet 6_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Global incidence rates of pancreatitis have notably increased since 1999, while the overall burden of DALYs has decreased over the past 30 years. In the APC model, different age groups experienced varying risks. …”

Data Sheet 8_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Global incidence rates of pancreatitis have notably increased since 1999, while the overall burden of DALYs has decreased over the past 30 years. In the APC model, different age groups experienced varying risks. …”

Data Sheet 2_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Global incidence rates of pancreatitis have notably increased since 1999, while the overall burden of DALYs has decreased over the past 30 years. In the APC model, different age groups experienced varying risks. …”

Data Sheet 5_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Global incidence rates of pancreatitis have notably increased since 1999, while the overall burden of DALYs has decreased over the past 30 years. In the APC model, different age groups experienced varying risks. …”

Data Sheet 1_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Global incidence rates of pancreatitis have notably increased since 1999, while the overall burden of DALYs has decreased over the past 30 years. In the APC model, different age groups experienced varying risks. …”

Cardiovascular safety of Janus kinase inhibitors in inflammatory bowel disease: a systematic review and network meta-analysis by Huibin Yang (10486204)

“…</p> <p>Although a trend of increased cardiovascular risks was found considering dose, no significantly increased cardiovascular risk was associated with JAKinibs in IBD patients, and Deucravacitinib significantly decreased the risks of VTE and CVE.…”

DataSheet1_Effects of Qingjin Huatan decoction on pulmonary function and inflammatory mediators in acute exacerbations of chronic obstructive pulmonary disease: a systematic review... by Xuqin Du (8803772)

“…Compared to conventional treatment, QHD significantly improved pulmonary function, with increases in FEV1 (MD = 0.30, 95% CI: 0.26 to 0.34, p = 0.000), FVC (MD = 0.34, 95% CI: 0.27 to 0.41, p = 0.000), FEV1/FVC (MD = 6.07, 95% CI: 5.55 to 6.58, p = 0.000), and PaO₂ (MD = 7.20, 95% CI: 4.94 to 9.47, p = 0.000), and a decrease in PaCO₂ (MD = −5.37, 95% CI: 7.99 to −2.74, p = 0.000). …”

DataSheet2_Effects of Qingjin Huatan decoction on pulmonary function and inflammatory mediators in acute exacerbations of chronic obstructive pulmonary disease: a systematic review... by Xuqin Du (8803772)

“…Compared to conventional treatment, QHD significantly improved pulmonary function, with increases in FEV1 (MD = 0.30, 95% CI: 0.26 to 0.34, p = 0.000), FVC (MD = 0.34, 95% CI: 0.27 to 0.41, p = 0.000), FEV1/FVC (MD = 6.07, 95% CI: 5.55 to 6.58, p = 0.000), and PaO₂ (MD = 7.20, 95% CI: 4.94 to 9.47, p = 0.000), and a decrease in PaCO₂ (MD = −5.37, 95% CI: 7.99 to −2.74, p = 0.000). …”

Table1_Effects of Qingjin Huatan decoction on pulmonary function and inflammatory mediators in acute exacerbations of chronic obstructive pulmonary disease: a systematic review and... by Xuqin Du (8803772)

“…Compared to conventional treatment, QHD significantly improved pulmonary function, with increases in FEV1 (MD = 0.30, 95% CI: 0.26 to 0.34, p = 0.000), FVC (MD = 0.34, 95% CI: 0.27 to 0.41, p = 0.000), FEV1/FVC (MD = 6.07, 95% CI: 5.55 to 6.58, p = 0.000), and PaO₂ (MD = 7.20, 95% CI: 4.94 to 9.47, p = 0.000), and a decrease in PaCO₂ (MD = −5.37, 95% CI: 7.99 to −2.74, p = 0.000). …”

Pathogenicity variation of CC4821 <i>Neisseria meningitidis</i> in China from 2005 to 2024 by Xueping Liu (22489348)

“…<p dir="ltr"><a href="" target="_blank">This study evaluated the distribution and pathogenicity of CC4821 isolates collected between 2005 and 2024 based on sources, serogroups, and time of isolation, including</a><a href="" target="_blank"> adhesion and invasion, and the ability to induce inflammatory responses and apoptosis. Results showed a significant increase in the recent prevalence of serogroup B isolates and enhanced adhesion and invasion abilities, whereas serogroup C isolates decreased significantly in number and decreased adhesion and invasion abilities. …”

Post-marketing safety of panitumumab: a real-world pharmacovigilance study by Heli Wen (20459923)

“…Age and sex subgroup analyses revealed specific risks, such as polyneuropathy and gene mutation in those under 65 years of age, decreased neutrophil count and peripheral sensory neuropathy in those over 65 years of age, and febrile neutropenia in men. …”

Table 1_Esmolol improves sepsis outcomes through cardiovascular and immune modulation.docx by Da Jing (404219)

“…Background<p>Sepsis poses significant mortality risks. Esmolol, a β1-adrenergic blocker, may improve outcomes through cardiovascular and immune modulation. …”

Image 2_Evaluating dexmedetomidine in mitigating emergence agitation and perioperative complications in pediatric tonsillectomy and/or adenoidectomy: a systematic review and meta-a... by Jihong He (3527105)

“…Subgroup analysis of delivery methods, timing, and dosage (Dex ≥0.5 μg/kg) indicated that Dex significantly decreased the incidence of EA (P < 0.05). …”