Data Sheet 1_Association between interleukin gene polymorphisms and the risk of pneumoconiosis: a systematic review and meta-analysis.zip حسب Lu Liu (171341)

"…The IL-6 -634 mutant significantly decreased silicosis and CWP risk. Additional large-scale replication studies are needed to elucidate the precise role of various IL SNPs in the etiology of pneumoconiosis.…"

3D culture raw data حسب Yaojun Luo (20296512)

"…<p dir="ltr"><a href="" target="_blank">Obesity poses a significant global health threat, particularly due to the </a>vital role of excessive visceral adipose tissue in metabolic dysfunction.…"

Data Sheet 1_Global, regional, and national burdens of pancreatic cancer attributable to smoking from 1990 to 2021 and the projections to 2035:a systematic analysis from the global... حسب Roubing Du (21449324)

"…</p>Results<p>Globally, the ASDR and ASMR of the disease demonstrated a decreasing trend. The burden was significantly higher among males, the middle-aged, and the elderly population. …"

Table 1_Effects of eculizumab and rituximab on visual function, motor function and social quality in patients with NMOSD: a comparative study.docx حسب Yihan Liu (2258221)

"…</p>Conclusion<p>NMOSD significantly impairs visual, motor, and social functions. …"

Image_1_What can be observed in intervertebral cartilage endplate with aging? An animal model study of excessive axial mechanical loading.PNG حسب Zhouyang Hu (8410554)

"…MRI analysis revealed significant degenerative changes in the loaded Co8/9 CEP, including decreased signal intensity and the formation of Schmorl’s nodes at 8 and 12 weeks. …"

Image 3_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.tif حسب Zechen Zhang (11702123)

"…These findings support its role in bone metabolism, though further long-term studies are needed to confirm clinical benefits, such as increased bone mineral density.…"

Image 1_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.tif حسب Zechen Zhang (11702123)

"…These findings support its role in bone metabolism, though further long-term studies are needed to confirm clinical benefits, such as increased bone mineral density.…"

Data Sheet 1_Investigation of the physiological and molecular regulatory mechanism of soluble sugar metabolism in Lavandula angustifolia Mill. under cold stress.docx حسب Yuchen Liang (8596404)

"…The results indicate the decomposition of starch into soluble sugars plays a crucial role in osmotic regulation, facilitating subsequent sugar metabolism in L. angustifolia under cold stress. …"

Table 1_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.docx حسب Zechen Zhang (11702123)

"…These findings support its role in bone metabolism, though further long-term studies are needed to confirm clinical benefits, such as increased bone mineral density.…"

Data Sheet 1_Association of dietary index for gut microbiota and cardiovascular diseases in American adults: evidence from National Health and Nutrition Examination Survey 1999–201... حسب Hong Luo (205745)

"…Background<p>As a significant health burden, cardiovascular disease (CVD) contributes substantially to global disease and death rates. …"

Image 4_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.tif حسب Zechen Zhang (11702123)

"…These findings support its role in bone metabolism, though further long-term studies are needed to confirm clinical benefits, such as increased bone mineral density.…"

Data Sheet 1_Integration of hepatic lipidomics and transcriptomics reveals dysregulation of lipid metabolism in a golden hamster model of visceral leishmaniasis.zip حسب Dongmei Yuan (291583)

"…Studies suggest that lipids play a crucial role in the survival of Leishmania parasites in mammalian hosts. …"

Image 2_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.tif حسب Zechen Zhang (11702123)

"…These findings support its role in bone metabolism, though further long-term studies are needed to confirm clinical benefits, such as increased bone mineral density.…"

Table 1_Cytokine dynamics in the blood and cerebrospinal fluid of HIV/AIDS patients with cryptococcal meningitis receiving antifungal therapy.docx حسب Rui Su (822125)

"…Over 28 days of antifungal treatment, significant decreases in the CSF levels of IL-2 and IL-10 and the plasma levels of IL-10 and IL-4 were observed. …"

Table 1_Association between oxidative balance score and methylation cycle biomarkers in US adults: insights from the national health and nutrition examination survey.docx حسب Xuna Liu (16988607)

"…RCS regression analysis revealed that with the increase in OBS, serum folate, RBC folate, vitamin B6, and vitamin B12 also increased, while HCY and MMA decreased.</p>Conclusion<p>Our findings demonstrate a significant relationship between OBS and the methylation cycle. …"

Table 1_A murine model of gestational diabetes reveals MASLD risk and alterations in markers of hepatic mitochondrial metabolism.docx حسب Grace E. Shryack (21596426)

"…</p>Results<p>Progressing gestation in both CD and GDM dams significantly decreased protein and mRNA markers of hepatic mitochondrial biogenesis (Pgc1-α, Tfam), autophagy (Atg5, Sqstm1), mitophagy (Pink1, Bnip3) and lipid handling (Ampk, pAMPK/AMPK, FAS, ACC, pACC, Mttp) with a main effect for time (P<0.05). …"

Data Sheet 1_What regulates decomposition in agroecosystems? Insights from reading the tea leaves.pdf حسب Marshall D. McDaniel (4341325)

"…A random forest regression model showed that soil temperature was the strongest predictor of green tea decomposition, but a soil health score also played a significant role in predicting the mass remaining. Soil texture and nutrient availability best predicted rooibos tea decomposition. …"

Identification of a Novel Virulence Factor in <i>Klebsiella pneumoniae</i> through CpxR-Dependent Transcriptional Activation حسب Runze Wang (21792959)

"…Among the genes exhibiting significantly decreased expression upon <i>cpxR</i> deletion<i>, </i>we identified a novel potential virulence factor KPHS_28080. …"

Data Sheet 1_Cytosolic phospholipase A2 links tau pathology to insulin signaling impairment in Alzheimer’s disease.pdf حسب Faruk Hossen (20275670)

"…Specifically, we found significant decreases in insulin receptor-α (IR-α) and insulin receptor-β (IR-β) expression, along with increased levels of phospho-insulin receptor substrate 1 at Ser307 [p-IRS-1 (Ser307)] and decreased levels of p-IRS-1 (Tyr895), compared to wild-type (WT) mice. …"

Image 2_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif حسب Helena Hernández-Cuervo (9956465)

"…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1^−/− mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …"