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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
role decrease » fold decrease (Expand Search), rate decreased (Expand Search), road decreased (Expand Search)
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2841
Table 1_Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer.docx
Published 2025“…A higher immune infiltration rate and lower IC50 values of anticancer drugs were significant in the high-risk group. In cellular experiments, Following MAN1B1 knockdown, in cell assays, the colony formation, migration, and invasion ability of HCT116 and HT29 cell lines decreased.…”
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2842
Data Sheet 1_Interaction between nasal epithelial cells and Tregs in allergic rhinitis responses to allergen via CCL1/CCR8.pdf
Published 2025“…In the AR + Derp1 group, TSLP was higher, and CCL1 protein levels were decreased. There were no significant differences in IL-25, TGF-β and IL-10. …”
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2843
Table 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.xlsx
Published 2025“…</p>Conclusion<p>Herein, carvedilol demonstrated significant anti-fibrotic effects on human lung fibroblasts in vitro, thus presenting great potential as an anti-IPF treatment. …”
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2844
Image4_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff
Published 2024“…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …”
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2845
Table 1_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.xlsx
Published 2025“…Introduction<p>Regulatory T cells (Tregs) play a crucial role in maintaining immune tolerance by suppressing immune responses against pathogens. …”
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2846
Image 4_Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.tif
Published 2025“…Treatment with these inhibitors also impacts neutrophil redox status, migration, and apoptosis without significantly changing overall bioenergetics.</p>Conclusions<p>Together, these results demonstrate that mitochondrial metabolism is dynamically remodeled and plays a significant role in neutrophils. …”
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2847
Presentation 1_Acupoint catgut embedding alleviates experimental autoimmune encephalomyelitis by modulating neuroinflammation and potentially inhibiting glia activation through JNK...
Published 2025“…</p>Methods<p>This study investigated the roles and potential mechanisms of the effects of ACE in treating experimental autoimmune encephalomyelitis (EAE), a frequently used animal model of autoimmune neuroinflammation. …”
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2848
Supplementary file 4_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf
Published 2025“…Introduction<p>Regulatory T cells (Tregs) play a crucial role in maintaining immune tolerance by suppressing immune responses against pathogens. …”
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2849
Table 2_Leucocalocybe mongolica inoculation enhances rice growth by reallocating resources from flavonoid defense to development via MYB/bHLH/WRKY networks.xlsx
Published 2025“…Pearson correlation analyses underscored negative associations between flavonoid levels and growth traits, highlighting LY9’s role in reallocating resources from defense to growth. …”
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2850
DataSheet1_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.pdf
Published 2024“…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …”
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2851
Data Sheet 2_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”
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2852
Data Sheet 2_Screening of neurotransmitter receptor modulators reveals novel inhibitors of influenza virus replication.pdf
Published 2025“…In a mouse model of lethal influenza, isoxsuprine significantly decreased lung viral titers, mitigated pulmonary inflammation, and enhanced survival rates. …”
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2853
Image 1_MicroRNA-27b alleviates septic cardiomyopathy by targeting the Mff/MAVS axis.tif
Published 2025“…Objective<p>To investigate the protective role of microRNA-27b (miR-27b) in septic cardiomyopathy (SCM) and its regulatory mechanism on the mitochondrial fission factor (Mff)/mitochondrial antiviral signaling protein (MAVS) axis.…”
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2854
DataSheet3_Dissecting the importance and origin of circulating myokines in gastric cancer cachexia.xlsx
Published 2024“…Background<p>Some experimental data suggest that myokines may play an important role in developing cancer-associated cachexia (CAC), but their relevance in humans remains poorly explored. …”
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2855
Image 1_Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.tif
Published 2025“…Treatment with these inhibitors also impacts neutrophil redox status, migration, and apoptosis without significantly changing overall bioenergetics.</p>Conclusions<p>Together, these results demonstrate that mitochondrial metabolism is dynamically remodeled and plays a significant role in neutrophils. …”
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2856
Antioxidants gene expressions in two tissues suspected to be involved in Decompression Sickness (DCS) triggering, in DCS resistant rats_Data
Published 2025“…They also highlight a possible key role of the liver and the mitochondria in DCS triggering, with a possible lower ROS production in resistant rats.…”
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2857
Dexmedetomidine improves septic acute kidney injury by inhibiting inflammation and oxidative stress through the activation of the Pink1/Park2 autophagy pathway
Published 2025“…These preliminary findings highlight dexmedetomidine’s potential role in SAKI management and warrant further validation in large scale studies.…”
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2858
Data Sheet 4_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx
Published 2025“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”
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2859
Image 1_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif
Published 2025“…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …”
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2860
Image 2_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Burden o...
Published 2025“…Decomposition analysis highlighted the role of epidemiological improvements, balanced by the impacts of population growth and aging. …”