Showing 2,841 - 2,860 results of 4,114 for search '(( significant decrease decrease ) OR ( significant role decrease ))~', query time: 0.41s Refine Results
  1. 2841

    Table 1_Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer.docx by Wenbing Zhang (152972)

    Published 2025
    “…A higher immune infiltration rate and lower IC50 values of anticancer drugs were significant in the high-risk group. In cellular experiments, Following MAN1B1 knockdown, in cell assays, the colony formation, migration, and invasion ability of HCT116 and HT29 cell lines decreased.…”
  2. 2842

    Data Sheet 1_Interaction between nasal epithelial cells and Tregs in allergic rhinitis responses to allergen via CCL1/CCR8.pdf by Jichao Sha (20756840)

    Published 2025
    “…In the AR + Derp1 group, TSLP was higher, and CCL1 protein levels were decreased. There were no significant differences in IL-25, TGF-β and IL-10. …”
  3. 2843

    Table 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.xlsx by Maria Jordan (10265489)

    Published 2025
    “…</p>Conclusion<p>Herein, carvedilol demonstrated significant anti-fibrotic effects on human lung fibroblasts in vitro, thus presenting great potential as an anti-IPF treatment. …”
  4. 2844

    Image4_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.tiff by Alexandra Coello-Camba (6489533)

    Published 2024
    “…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …”
  5. 2845

    Table 1_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.xlsx by Yanling Wen (552195)

    Published 2025
    “…Introduction<p>Regulatory T cells (Tregs) play a crucial role in maintaining immune tolerance by suppressing immune responses against pathogens. …”
  6. 2846

    Image 4_Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.tif by Jorgo Lika (21189020)

    Published 2025
    “…Treatment with these inhibitors also impacts neutrophil redox status, migration, and apoptosis without significantly changing overall bioenergetics.</p>Conclusions<p>Together, these results demonstrate that mitochondrial metabolism is dynamically remodeled and plays a significant role in neutrophils. …”
  7. 2847

    Presentation 1_Acupoint catgut embedding alleviates experimental autoimmune encephalomyelitis by modulating neuroinflammation and potentially inhibiting glia activation through JNK... by Xiaofang Liu (398453)

    Published 2025
    “…</p>Methods<p>This study investigated the roles and potential mechanisms of the effects of ACE in treating experimental autoimmune encephalomyelitis (EAE), a frequently used animal model of autoimmune neuroinflammation. …”
  8. 2848

    Supplementary file 4_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf by Yanling Wen (552195)

    Published 2025
    “…Introduction<p>Regulatory T cells (Tregs) play a crucial role in maintaining immune tolerance by suppressing immune responses against pathogens. …”
  9. 2849

    Table 2_Leucocalocybe mongolica inoculation enhances rice growth by reallocating resources from flavonoid defense to development via MYB/bHLH/WRKY networks.xlsx by Mingzheng Duan (11630632)

    Published 2025
    “…Pearson correlation analyses underscored negative associations between flavonoid levels and growth traits, highlighting LY9’s role in reallocating resources from defense to growth. …”
  10. 2850

    DataSheet1_Seawater temperature drives the diversity of key cyanobacteria (Synechococcus and Prochlorococcus) in a warming sea.pdf by Alexandra Coello-Camba (6489533)

    Published 2024
    “…<p>The picocyanobacteria genera Prochlorococcus and Synechococcus play a significant role globally, dominating the primary production in warm and oligotrophic tropical and subtropical areas, which represent the largest oceanic ecosystem. …”
  11. 2851

    Data Sheet 2_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

    Published 2025
    “…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”
  12. 2852

    Data Sheet 2_Screening of neurotransmitter receptor modulators reveals novel inhibitors of influenza virus replication.pdf by Yarou Gao (20620991)

    Published 2025
    “…In a mouse model of lethal influenza, isoxsuprine significantly decreased lung viral titers, mitigated pulmonary inflammation, and enhanced survival rates. …”
  13. 2853

    Image 1_MicroRNA-27b alleviates septic cardiomyopathy by targeting the Mff/MAVS axis.tif by Xincai Wang (7819064)

    Published 2025
    “…Objective<p>To investigate the protective role of microRNA-27b (miR-27b) in septic cardiomyopathy (SCM) and its regulatory mechanism on the mitochondrial fission factor (Mff)/mitochondrial antiviral signaling protein (MAVS) axis.…”
  14. 2854

    DataSheet3_Dissecting the importance and origin of circulating myokines in gastric cancer cachexia.xlsx by Marek Sierzega (3846406)

    Published 2024
    “…Background<p>Some experimental data suggest that myokines may play an important role in developing cancer-associated cachexia (CAC), but their relevance in humans remains poorly explored. …”
  15. 2855

    Image 1_Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.tif by Jorgo Lika (21189020)

    Published 2025
    “…Treatment with these inhibitors also impacts neutrophil redox status, migration, and apoptosis without significantly changing overall bioenergetics.</p>Conclusions<p>Together, these results demonstrate that mitochondrial metabolism is dynamically remodeled and plays a significant role in neutrophils. …”
  16. 2856

    Antioxidants gene expressions in two tissues suspected to be involved in Decompression Sickness (DCS) triggering, in DCS resistant rats_Data by Emmanuel Dugrenot (18447504)

    Published 2025
    “…They also highlight a possible key role of the liver and the mitochondria in DCS triggering, with a possible lower ROS production in resistant rats.…”
  17. 2857

    Dexmedetomidine improves septic acute kidney injury by inhibiting inflammation and oxidative stress through the activation of the Pink1/Park2 autophagy pathway by Qiuxia Liao (21507933)

    Published 2025
    “…These preliminary findings highlight dexmedetomidine’s potential role in SAKI management and warrant further validation in large scale studies.…”
  18. 2858

    Data Sheet 4_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

    Published 2025
    “…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”
  19. 2859

    Image 1_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif by Inssaf Berkiks (15350248)

    Published 2025
    “…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …”
  20. 2860

    Image 2_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Burden o... by Yangtian Jiao (21725018)

    Published 2025
    “…Decomposition analysis highlighted the role of epidemiological improvements, balanced by the impacts of population growth and aging. …”