Data Sheet 1_Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.docx حسب Xiongbao Wang (12508462)

"…Background<p>Lysomembrane-associated protein 1 (LAMP1), known to exhibit differential expression in various tumor types and play a crucial role in the development of tumors. Clear cell Renal Cell Carcinoma (ccRCC) is still the most common pathological type of renal carcinoma with poor prognosis. …"

Table1_Chaihu Shugan powder restores fatty acid synthesis to alleviate insulin resistance in metabolic syndrome by regulating the LXRα/SREBP-1 signaling pathway.XLSX حسب Sisi Lei (10999575)

"…Background<p>Metabolic syndrome (MS) is a significant risk factor for cardiovascular and cerebrovascular diseases, primarily driven by insulin resistance (IR). …"

Data Sheet 1_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.zip حسب Haoming Shen (3816988)

"…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…"

Image 5_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa... حسب Jiaochen Luan (9704384)

"…</p>Objective<p>This study aims to explore the role of Fatty acid synthase (Fasn) in hypertension-induced ED and evaluate the therapeutic potential of the Fasn inhibitor C75.…"

Table 8_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx حسب Wenjun Wang (314231)

"…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…"

Data Sheet 1_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through a... حسب Jiaochen Luan (9704384)

"…</p>Objective<p>This study aims to explore the role of Fatty acid synthase (Fasn) in hypertension-induced ED and evaluate the therapeutic potential of the Fasn inhibitor C75.…"

Data Sheet 1_Decanoic acid, an MCT dietary component, alleviates cognitive impairment, cellular senescence, and promotes autophagy in accelerated aging and neurotoxic mouse models... حسب Shreshta Jain (12274885)

"…</p>Results<p>Decanoic acid significantly improved learning and memory performance, enhanced antioxidant enzyme activity (superoxide dismutase, reduced glutathione, catalase), promoted autophagy by inhibiting mTOR, reduced cellular senescence (β-galactosidase-positive cells), and decreased amyloid-β toxicity. …"

Table_2_Microclimate shapes the phylosymbiosis of rodent gut microbiota in Jordan’s Great Rift Valley.XLSX حسب Enas Al-khlifeh (17286364)

"…<p>Host phylogeny and the environment play vital roles in shaping animal microbiomes. However, the effects of these variables on the diversity and richness of the gut microbiome in different bioclimatic zones remain underexplored. …"

Image 2_High-value valorization of Periplaneta americana residue: intestinal health regulation in pre-bred hens and circular economy applications.tiff حسب Sicai Tao (22829048)

"…Additionally, ileal and jejunal pH values decreased significantly with increasing PAR levels (p < 0.05), and the intestinal microbiota diversity remained stable. …"

Scale and environmental data for the analysis of year class growth of coregonids from Lake Starnberg حسب Maxim Teichert (20796416)

"…During the observed period, phosphorus concentrations decreased, indicating reduced nutrient availability, whereas spring temperatures showed no significant long-term trend. …"

Table_1_Microclimate shapes the phylosymbiosis of rodent gut microbiota in Jordan’s Great Rift Valley.XLSX حسب Enas Al-khlifeh (17286364)

"…<p>Host phylogeny and the environment play vital roles in shaping animal microbiomes. However, the effects of these variables on the diversity and richness of the gut microbiome in different bioclimatic zones remain underexplored. …"

Image 1_High-value valorization of Periplaneta americana residue: intestinal health regulation in pre-bred hens and circular economy applications.tiff حسب Sicai Tao (22829048)

"…Additionally, ileal and jejunal pH values decreased significantly with increasing PAR levels (p < 0.05), and the intestinal microbiota diversity remained stable. …"

Table1_Characterization of morphological and chemical changes using atomic force microscopy and metabolism assays: the relationship between surface wax and skin greasiness in apple... حسب Yanqing Yang (1698535)

"…</p>Results<p>AFM results revealed that wax crystals disappeared as skin greasiness increased, accompanied by significant declines in roughness parameters Ra, Rq, Rmax, and Rz, which decreased by 70% to 85%. …"

Data Sheet 1_Alpha-synuclein knockout impairs melanoma development and alters DNA damage repair in the TG3 mouse model in a sex-dependent manner.docx حسب Moriah R. Arnold (20908868)

"…Furthermore, decreased tumor volume is correlated with a decreased DNA damage signature and increased apoptotic markers, indicating a role for αSyn in modulating the DNA damage response (DDR) pathway. …"

Data Sheet 2_Gut microbiota metabolite acetate mediates free fatty acid receptor 2 expression to alleviate atopic dermatitis.zip حسب Siqi Ye (9350531)

"…Acetate supplementation in AD mice significantly ameliorated 2,4-dinitrobenzene (DNCB)-induced dermatitis, as evidenced by reduced skin lesion severity, lower dermatitis scores, and decreased epidermal thickening. …"

Data Sheet 1_Gut microbiota metabolite acetate mediates free fatty acid receptor 2 expression to alleviate atopic dermatitis.zip حسب Siqi Ye (9350531)

"…Acetate supplementation in AD mice significantly ameliorated 2,4-dinitrobenzene (DNCB)-induced dermatitis, as evidenced by reduced skin lesion severity, lower dermatitis scores, and decreased epidermal thickening. …"

Supplementary Material for: Seraph-100 hemoperfusion for management of severe COVID-19: Assessment of serum and plasma analytes pre- and post-filtration حسب Rouse M. (20413172)

"…However, multiple circulating proteins with roles in inflammation, endothelial/epithelial damage and/or angiogenesis decreased significantly across the filter. …"

Data Sheet 1_Boundary currents in the Bransfield Strait: near-surface interbasin water volume and heat exchange.pdf حسب Marta Veny (20937656)

"…Seasonal shifts in near-surface volume and heat balances, driven by wind stress and temperature gradients, highlight the critical role of these boundary currents in shaping local hydrography and sea ice dynamics. …"

Data Sheet 1_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.pdf حسب Peerapon Kiatkittikul (22801874)

"…Background<p>Neuroinflammation plays an important role in progression of Parkinson disease (PD). [¹⁸F]SMBT-1 is a promising novel radiotracer for in vivo evaluation of reactive astrogliosis.…"

Table 1_Characterizing HLA-A2-restricted CD8+ T-cell epitopes and immune responses to Omicron variants in SARS-CoV-2-inactivated vaccine recipients.doc حسب Chanchan Xiao (9522614)

"…We identified two epitopes associated with decreased CD8 T-cell reactivity post-Omicron variant emergence. …"