Showing 3,121 - 3,140 results of 4,114 for search '(( significant decrease decrease ) OR ( significant role decrease ))~', query time: 0.30s Refine Results
  1. 3121

    Table 1_Oxyresveratrol as a novel ferroptosis inducer exhibits anticancer activity against breast cancer via the EGFR/PI3K/AKT/GPX4 signalling axis.xlsx by Lei Xiang (528500)

    Published 2025
    “…Introduction<p>Oxyresveratrol (ORes) exhibits significant anticancer activity, particularly against breast cancer. …”
  2. 3122

    Data Sheet 1_Oxyresveratrol as a novel ferroptosis inducer exhibits anticancer activity against breast cancer via the EGFR/PI3K/AKT/GPX4 signalling axis.pdf by Lei Xiang (528500)

    Published 2025
    “…Introduction<p>Oxyresveratrol (ORes) exhibits significant anticancer activity, particularly against breast cancer. …”
  3. 3123

    Supplementary file 1_Hydroxysafflor yellow A alleviates oxidative stress and inflammatory damage in the livers of mice with nonalcoholic fatty liver disease and modulates gut micro... by Liang Wu (131111)

    Published 2025
    “…(safflower), has shown therapeutic potential in various inflammatory diseases. However, its role in alleviating inflammation and oxidative stress in non-alcoholic fatty liver disease (NAFLD) remains unclear. …”
  4. 3124

    Video 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

    Published 2025
    “…</p>Methods<p>To investigate the role of the endolysosomal two-pore channel 2 (TPC2) in HCC, we employed genetic and pharmacological approaches, including TPC2 knockout (KO) and pharmacological inhibition using SG094. …”
  5. 3125

    Video 5_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

    Published 2025
    “…</p>Methods<p>To investigate the role of the endolysosomal two-pore channel 2 (TPC2) in HCC, we employed genetic and pharmacological approaches, including TPC2 knockout (KO) and pharmacological inhibition using SG094. …”
  6. 3126

    Image 2_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff by Peerapon Kiatkittikul (22801874)

    Published 2025
    “…Background<p>Neuroinflammation plays an important role in progression of Parkinson disease (PD). [<sup>18</sup>F]SMBT-1 is a promising novel radiotracer for in vivo evaluation of reactive astrogliosis.…”
  7. 3127

    Image 4_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff by Peerapon Kiatkittikul (22801874)

    Published 2025
    “…Background<p>Neuroinflammation plays an important role in progression of Parkinson disease (PD). [<sup>18</sup>F]SMBT-1 is a promising novel radiotracer for in vivo evaluation of reactive astrogliosis.…”
  8. 3128

    Video 1_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

    Published 2025
    “…</p>Methods<p>To investigate the role of the endolysosomal two-pore channel 2 (TPC2) in HCC, we employed genetic and pharmacological approaches, including TPC2 knockout (KO) and pharmacological inhibition using SG094. …”
  9. 3129

    Image 2_Characterizing HLA-A2-restricted CD8+ T-cell epitopes and immune responses to Omicron variants in SARS-CoV-2-inactivated vaccine recipients.tif by Chanchan Xiao (9522614)

    Published 2025
    “…We identified two epitopes associated with decreased CD8 T-cell reactivity post-Omicron variant emergence. …”
  10. 3130

    Table 1_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.docx by Peerapon Kiatkittikul (22801874)

    Published 2025
    “…Background<p>Neuroinflammation plays an important role in progression of Parkinson disease (PD). [<sup>18</sup>F]SMBT-1 is a promising novel radiotracer for in vivo evaluation of reactive astrogliosis.…”
  11. 3131

    Image 1_Ketogenic diet–induced changes in methylation status and neuropeptide signaling: relationships between S-adenosylmethionine (AdoMet), orexin-A, and metabolic health.pdf by Laura Mosca (704904)

    Published 2025
    “…Circulating AdoMet (−75.7%) and Orexin-A (−7.2%) levels also decreased significantly. AdoMet levels positively correlated with body weight, BMI, visceral adipose tissue, total cholesterol, fasting glycemia, triglycerides, HbA1c, and notably Orexin-A (R<sup>2</sup> = 0.3848, p < 0.0001).…”
  12. 3132

    Data Sheet 1_Therapeutic efficacy of a galactoglucan from Pleurotus citrinopileatus in constipation: modulation of aquaporin signaling and intestinal barrier.pdf by Yi Gao (112914)

    Published 2025
    “…The oral administration of PCP-g resulted in a significant reduction in constipation symptoms, as indicated by an increase in fecal water content, normalization of pellet formation, enhancement of total fecal mass, decreased latency to the first stool, and improved intestinal propulsion. …”
  13. 3133

    Causal associations between gut <i>Bifidobacteriaceae</i> and transplant failure: a Mendelian randomization study by Han Yan (126662)

    Published 2024
    “…</p> <p><b>Conclusion:</b> The <i>Bifidobacteriaceae</i> may play a crucial role in the mechanism of transplant failure. These study results contribute to elucidating the mechanisms underlying transplant failure.…”
  14. 3134

    Table 1_Analysis of growth variations and expression patterns of auxin response factor gene family in Fallopia multiflora under different light qualities.xlsx by Wenze Liu (22817513)

    Published 2025
    “…Results showed that the blue-light treatment group significantly increased the leaf area by 46.19% and chlorophyll content by 7.35%, decreased the plant height by 20.92%, and increased the THSG content in roots by 28.37% and in stems by 27.15%. …”
  15. 3135

    Video 6_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

    Published 2025
    “…</p>Methods<p>To investigate the role of the endolysosomal two-pore channel 2 (TPC2) in HCC, we employed genetic and pharmacological approaches, including TPC2 knockout (KO) and pharmacological inhibition using SG094. …”
  16. 3136

    Image 3_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff by Peerapon Kiatkittikul (22801874)

    Published 2025
    “…Background<p>Neuroinflammation plays an important role in progression of Parkinson disease (PD). [<sup>18</sup>F]SMBT-1 is a promising novel radiotracer for in vivo evaluation of reactive astrogliosis.…”
  17. 3137

    Data Sheet 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx by Lina Ouologuem (22489549)

    Published 2025
    “…</p>Methods<p>To investigate the role of the endolysosomal two-pore channel 2 (TPC2) in HCC, we employed genetic and pharmacological approaches, including TPC2 knockout (KO) and pharmacological inhibition using SG094. …”
  18. 3138

    Table 1_MIKC-type MADS-box transcription factor OsMADS31 positively regulates salinity tolerance in rice.xlsx by Xiaolin Yin (359202)

    Published 2025
    “…Conversely, compared with WT plants, 3,3’-diaminobenzidine (DAB) and nitroblue tetrazolium (NBT) staining intensities as well as malondialdehyde (MDA) content were significantly higher in osmads31 mutants and significantly lower in OE lines. …”
  19. 3139

    Image 1_Characterizing HLA-A2-restricted CD8+ T-cell epitopes and immune responses to Omicron variants in SARS-CoV-2-inactivated vaccine recipients.tif by Chanchan Xiao (9522614)

    Published 2025
    “…We identified two epitopes associated with decreased CD8 T-cell reactivity post-Omicron variant emergence. …”
  20. 3140

    Video 4_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

    Published 2025
    “…</p>Methods<p>To investigate the role of the endolysosomal two-pore channel 2 (TPC2) in HCC, we employed genetic and pharmacological approaches, including TPC2 knockout (KO) and pharmacological inhibition using SG094. …”