Showing 3,621 - 3,640 results of 4,114 for search '(( significant decrease decrease ) OR ( significant role decrease ))~', query time: 0.39s Refine Results
  1. 3621

    Supplementary file 1_Therapeutic potential of formononetin in cirrhotic portal hypertension: modulating hepatic fibrosis, macrophage polarization, and lymphangiogenesis.doc by Zhenghao Wu (9732511)

    Published 2025
    “…For in vitro experiments, hepatic stellate cells, macrophages and lymphatic endothelial cells were used to observe the multiple effects of FN.</p>Results<p>FN significantly ameliorated portal pressure in cirrhosis-induced PHT, improved liver function, and reduced liver fibrosis and hepatic stellate cell activation with decreased SMAD3 protein expression. …”
  2. 3622

    Supplementary Material for: Splice variant of retinal G-protein-coupled receptor deletion (RGR-d)-mediated dysregulation of autophagy increases the susceptibility to age-related ma... by Guo Y. (2986464)

    Published 2024
    “…Beclin-1 and LC3II/I expression levels were significantly decreased and that of P62 was elevated in RGR-d cells after PA stimulation. …”
  3. 3623

    Data Sheet 1_Impact of endurance training on mitochondrial H2O2 production and NRF2 levels in different rat organs.pdf by Lukasz Galganski (22442002)

    Published 2025
    “…The level of malondialdehyde, a marker of oxidative damage, did not increase in the examined tissues, except the lungs, where it even decreased. Superoxide dismutase 1 levels increased in the lung, brain, and skeletal muscle, but decreased in the heart and remained unchanged in the liver. …”
  4. 3624

    DataSheet1_UV-B induced flavonoid accumulation and related gene expression in blue- grained wheat at different periods of time.zip by Li Li (14993)

    Published 2024
    “…</p>Discussion<p>The expression of these genes decreased after early UV-B irradiation, but increased later. …”
  5. 3625

    DataSheet_1_RETRACTED: Tregs depletion aggravates activation of astrocytes by modulating IL-10/GXP4 following cerebral infarction.docx by Shuai Wang (109515)

    Published 2024
    “…</p>Results<p>In the tMCAO mouse model, depletion of tregs protected against activation of astrocyte and significantly decreased FSP1, IL-6, IL-2, and NLRP3 expression levels, while partially reversing the changes in Tregs. …”
  6. 3626

    Table 1_Exogenous myo-inositol enhances drought tolerance in maize seedlings by antioxidant defense, and photosynthetic efficiency.docx by Yuqi Liu (501183)

    Published 2025
    “…</p>Methods<p>In this study, we aimed to investigate the role of exogenous myo-inositol (MI) in alleviating drought stress in maize seedlings. …”
  7. 3627

    Image 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.jpeg by Wenqiao Jia (12356306)

    Published 2025
    “…Gain- and loss-of-function studies in PCa cell lines and mouse models were performed to characterize the role of PCP4 in tumor progression. A series of molecular and biochemical experiments were carried out in PCa cell lines to investigate the mechanism underlying PCP4-mediated tumor suppression.…”
  8. 3628

    Raw data WB.pdf by Grazia Serino (21164993)

    Published 2025
    “…Moreover, miR-369-3p significantly decreased the release of pro-inflammatory cytokine IL-8. …”
  9. 3629

    Image 2_Modulation of fenestrated vasculature in the median eminence and area postrema in response to neurotoxin exposure and its impairment in aging.tif by Viana Q. Pham (22081163)

    Published 2025
    “…Circumventricular organs, characterized by the presence of fenestrated capillaries and absence of a blood–brain barrier (BBB), play a crucial role in controlling substance exchange between the brain and the blood. …”
  10. 3630

    data.zip by Zhizhang Dong (21158474)

    Published 2025
    “…Compared with the control group, the thickness of retina in the experimental group was significantly reduced (t=5, P=0.0075), the number of retinal pigment epithelium was statistically decreased (t=4.243, P=0.0132), and the pyrolytic related proteins NLRP3, Caspase-1, GSDMD, IL-1β and IL-18 were strongly red positive in retinal pigment epithelium (P<0.05). …”
  11. 3631

    Soil viral and microbial interactions facilitate microbial necromass carbon accumulation in the semiarid typical steppe under altered precipitation_Research data by Anonymous Author (7372229)

    Published 2025
    “…The results showed that decreased precipitation significantly reduced microbial necromass carbon (BNC, MNC, and BNC/MNC) and their relative contributions to SOC (BNC/SOC and MNC/SOC), whereas increased precipitation had relatively weaker effects. …”
  12. 3632

    Data Sheet 1_Diethyl butylmalonate attenuates cognitive deficits and depression in 5×FAD mice.docx by Lai Yuan (20136422)

    Published 2024
    “…Diethyl butylmalonate (DBM) has recently attracted extensive interest due to its anti-inflammatory role in macrophages. However, it is still unknown whether DBM has a beneficial effect on cognitive deficits and depression.…”
  13. 3633

    Table 1_The RNA-binding protein ProQ directly binds and regulates virulence genes in enterohemorrhagic Escherichia coli O157:H7.docx by Ye Qian (7400186)

    Published 2025
    “…In this study, we investigated the role of ProQ in enterohaemorrhagic Escherichia coli (EHEC), a non-invasive intestinal pathogen. …”
  14. 3634

    Table 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx by Wenqiao Jia (12356306)

    Published 2025
    “…Gain- and loss-of-function studies in PCa cell lines and mouse models were performed to characterize the role of PCP4 in tumor progression. A series of molecular and biochemical experiments were carried out in PCa cell lines to investigate the mechanism underlying PCP4-mediated tumor suppression.…”
  15. 3635
  16. 3636

    Data Sheet 1_Dynamic brain network reconfiguration following rTMS in males with cocaine use disorder.pdf by Chengjie Le (22099766)

    Published 2025
    “…Although FPCN-state self-transition decreased significantly following stimulation, it was not directly linked to craving improvement, indicating a potentially supportive but nonspecific role in perceptual recalibration. …”
  17. 3637

    Table 2_Deletion of the GntR8 transcriptional regulator impairs Brucella abortus intracellular survival and virulence by modulating stress response genes.docx by Shuwen Li (5058398)

    Published 2025
    “…In this study, we generated a gntR8 (BAB_RS24500) deletion strain (ΔgntR8) in B. abortus 2308 and systematically investigated its role in virulence. The results demonstrate that deletion of gntR8 markedly impairs intracellular survival of B. abortus in RAW264.7 cells and significantly reduces virulence in a mouse infection model. …”
  18. 3638

    <i>Aspergillus fumigatus</i> effector crpA orchestrates host prostaglandin signaling to promote fungal virulence by Gustavo Goldman (8849927)

    Published 2025
    “…Δ<i>crpA</i> conidia elicited decreased production of pro-inflammatory cytokines and increased production of anti-inflammatory cytokine IL-10 from murine macrophages and in the lungs of infected mice. …”
  19. 3639

    Image 1_Modulation of fenestrated vasculature in the median eminence and area postrema in response to neurotoxin exposure and its impairment in aging.tif by Viana Q. Pham (22081163)

    Published 2025
    “…Circumventricular organs, characterized by the presence of fenestrated capillaries and absence of a blood–brain barrier (BBB), play a crucial role in controlling substance exchange between the brain and the blood. …”
  20. 3640

    Data file. by Maryam Khalaji (21743611)

    Published 2025
    “…The results showed that mental fatigue significantly decreased QE duration (Mean difference = −138.75 ms, p = .0009) and fixation duration (Mean difference = 67.50 ms, p = .001), indicating a detrimental effect on sustained attention. …”