Search alternatives:
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
role decrease » fold decrease (Expand Search), rate decreased (Expand Search), road decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
role decrease » fold decrease (Expand Search), rate decreased (Expand Search), road decreased (Expand Search)
-
3981
Table 1_FBR2 modulates ferroptosis via the SIRT3/p53 pathway to ameliorate pulmonary fibrosis.docx
Published 2025“…The protective effects of FBR2 were reversed by Erastin, confirming the central role of ferroptosis in pulmonary fibrosis treatment. …”
-
3982
Image 1_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.tiff
Published 2025“…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”
-
3983
Table1_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX...
Published 2024“…</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. Pharmacological inhibition of S1pr2 alleviated secondary injury with reduced lesion volume, ROS generation, cerebral oedema, neurological deficits, and neuronal apoptosis; BBB disruption was also mitigated, accompanied by reduced degradation of tight junction proteins and decreased induction of matrix metalloproteinases-9 (MMP-9) post-TBI. …”
-
3984
Table 1_Resveratrol targeting MDM2/P53/PUMA axis to inhibit colonocyte apoptosis in DSS-induced ulcerative colitis mice.xlsx
Published 2025“…Additionally, we employed an Adeno-Associated Virus system to overexpress MDM2 in the colon and evaluate its protective role in DSS-induced UC.</p>Results<p>Resveratrol treatment effectively repaired colonic damage in the UC mouse model by significantly increasing colon length, reducing inflammatory cell infiltration, and mitigating mucosal injury. …”
-
3985
Image 8_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.tif
Published 2025“…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”
-
3986
Table 2_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx
Published 2024“…<p>Milk production traits play an important role in dairy cattle breeding, and single nucleotide polymorphisms can be used as effective molecular markers for milk production trait marker-assisted breeding in dairy cattle. …”
-
3987
Image 6_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.tiff
Published 2025“…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”
-
3988
Image 4_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.tif
Published 2025“…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”
-
3989
Image 7_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.tiff
Published 2025“…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”
-
3990
Table 2_FBR2 modulates ferroptosis via the SIRT3/p53 pathway to ameliorate pulmonary fibrosis.xlsx
Published 2025“…The protective effects of FBR2 were reversed by Erastin, confirming the central role of ferroptosis in pulmonary fibrosis treatment. …”
-
3991
Image 2_Hypothalamic FTO upregulates BDNF to promote GnRH expression through the PI3K/Akt pathway, leading to precocious puberty.tif
Published 2025“…</p>Results<p>Hypothalamic GnRH and FTO expression progressively increased whereas m6A methylation decreased during puberty. MeRIP-seq revealed significantly reduced m6A methylation of Bdnf mRNA in the arcuate nucleus (ARC) of female rats during early puberty. …”
-
3992
DataSheet1_Efferocytosis dysfunction in CXCL4-induced M4 macrophages: phenotypic insights in systemic sclerosis in vitro and in vivo.docx
Published 2024“…</p>Discussion<p>Altogether, our results support the role of CXCL4 on the impaired efferocytosis capacities of human macrophages from SSc patients and in SSc mice.…”
-
3993
Image 5_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.tiff
Published 2025“…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”
-
3994
Table 4_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.xlsx
Published 2025“…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”
-
3995
Image 1_Augmentation of bone formation by sympathectomy in rats as evaluated by [99mTc]Tc-MDP.png
Published 2025“…Background<p>The role of the sympathetic nervous system in bone metabolism remains unclear. …”
-
3996
Table 3_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx
Published 2024“…<p>Milk production traits play an important role in dairy cattle breeding, and single nucleotide polymorphisms can be used as effective molecular markers for milk production trait marker-assisted breeding in dairy cattle. …”
-
3997
Image 1_Hypothalamic FTO upregulates BDNF to promote GnRH expression through the PI3K/Akt pathway, leading to precocious puberty.tif
Published 2025“…</p>Results<p>Hypothalamic GnRH and FTO expression progressively increased whereas m6A methylation decreased during puberty. MeRIP-seq revealed significantly reduced m6A methylation of Bdnf mRNA in the arcuate nucleus (ARC) of female rats during early puberty. …”
-
3998
Data Sheet 1_Capsaicin induces ferroptosis via suppression of SLC7A11 activity and upregulation of ACSL4 mediated by AMPK in tongue squamous cell carcinoma.zip
Published 2025“…</p>Results<p>CAP significantly suppressed the viability of HN6 and CAL27 cells. …”
-
3999
Table 4_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx
Published 2024“…<p>Milk production traits play an important role in dairy cattle breeding, and single nucleotide polymorphisms can be used as effective molecular markers for milk production trait marker-assisted breeding in dairy cattle. …”
-
4000
Supplementary Material for: ACOT4 and ACOT6 activate Akt-mTOR pathway and inhibit calcium oxalate-induced renal tubular cell injury
Published 2025“…Conclusions: ACOT4 and ACOT6 could be protecting factors for kidney cell injury induced by CaOx via reducing apoptosis and activating Akt/mTOR signaling pathway. The study of the role of ACOT4 and ACOT6 in kidney cell injury provides a new insight into the cause of CaOx kidney stone formation. …”