Prediction of the effect of the 9 nsSNPs on AKT2 proteins’ structure and function by eight computational tools. by Sadia Afrin Runa (22504971)

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Age-standardised rates (per 100,000 population) of rheumatoid arthritis burden attributable to smoking in 1990 and 2021, and trends from 1990 to 2021, by GBD Super-Region. by Kaibin Lin (9911049)

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Minimal dataset for the study. by Kaibin Lin (9911049)

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Distribution of SNPs and their frequencies based on mutation classes. by Sadia Afrin Runa (22504971)

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Hydrogen bond interactions between Capivasertib (red) and the AKT2 protein (blue) as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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Hydrogen bond interactions between Ipatasertib (red) and the AKT2 protein (blue) as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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Hydrogen bond interactions between Akt1/Akt2-IN-1 (red) and the AKT2 protein (blue) as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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Predicted pathogenicity of R274H, Y265N, and R467W substitutions and their molecular mechanisms. by Sadia Afrin Runa (22504971)

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The Fig illustrates the effects of mutations on the stability, flexibility, compactness, and interactions of the AKT2-Akt1/Akt2-IN-1 through molecular dynamics simulations. by Sadia Afrin Runa (22504971)

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Non-covalent interactions between Capivasertib (ball stick) and the AKT2 protein as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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Burden of RA attributable to smoking in 2021 across 204 countries and territories. by Kaibin Lin (9911049)

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Sex and age differences in smoking-attributable RA burden in 2021. by Kaibin Lin (9911049)

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Non-covalent interactions between Akt1/Akt2-IN-1 (ball stick) and the AKT2 protein as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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Binding affinity of Akt1/Akt2-IN-1, Capivasertib, and Ipatasertib with AKT2 (wild and mutants) protein. by Sadia Afrin Runa (22504971)

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Superimposed structures of AKT2 native (green color) and mutant (red color) models to visualize the stereochemical conformation of wild type and mutant residues at (a) 274, (b) 265... by Sadia Afrin Runa (22504971)

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The Fig illustrates the effects of mutations on the stability, flexibility, compactness, and interactions of the AKT2-Ipatasertib complex through molecular dynamics simulations. by Sadia Afrin Runa (22504971)

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Non-covalent interactions between Ipatasertib (ball stick) and the AKT2 protein as predicted by molecular docking analyses. by Sadia Afrin Runa (22504971)

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Calycosin Inhibit PANoptosis and Alleviate Brain Damage: A Bioinformatics and Experimental Verification Approach by Huiyan An (20959966)

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Smoking-Attributable RA Burden from 2000 to 2021: Global Temporal Trends and Regional Differences in Smoking Prevalence and Burden Indicators. by Kaibin Lin (9911049)

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Relationship between SDI and smoking-attributable RA burden. by Kaibin Lin (9911049)

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