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741
Image 1_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.tif
Published 2025“…</p>Findings<p>Between 1990 and 2021, the global number of childhood ALL cases increased by 59.06%, reaching 168,879 cases in 2021, while ALL-related deaths and DALYs decreased by 66.71% and 66.13%, respectively. High- and high-middle SDI regions demonstrated significant improvements, driven by advances in healthcare and early diagnosis. …”
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742
Table 2_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx
Published 2025“…</p>Findings<p>Between 1990 and 2021, the global number of childhood ALL cases increased by 59.06%, reaching 168,879 cases in 2021, while ALL-related deaths and DALYs decreased by 66.71% and 66.13%, respectively. High- and high-middle SDI regions demonstrated significant improvements, driven by advances in healthcare and early diagnosis. …”
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743
Table 1_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx
Published 2025“…</p>Findings<p>Between 1990 and 2021, the global number of childhood ALL cases increased by 59.06%, reaching 168,879 cases in 2021, while ALL-related deaths and DALYs decreased by 66.71% and 66.13%, respectively. High- and high-middle SDI regions demonstrated significant improvements, driven by advances in healthcare and early diagnosis. …”
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744
Table 3_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx
Published 2025“…</p>Findings<p>Between 1990 and 2021, the global number of childhood ALL cases increased by 59.06%, reaching 168,879 cases in 2021, while ALL-related deaths and DALYs decreased by 66.71% and 66.13%, respectively. High- and high-middle SDI regions demonstrated significant improvements, driven by advances in healthcare and early diagnosis. …”
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745
<b>Canagliflozin-induced adaptive metabolism in bone</b>
Published 2025“…An integrOmics approach of source-matched bone tissue metabolome and bone marrow RNAseq indicated a positive correlation between the two omics data sets in male mice. …”
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746
Global, regional, and national trends in colorectal cancer from 2010 to 2021: an analysis of the global burden of disease study 2021
Published 2025“…Dietary and metabolic risk factors significantly contributed to CRC burden across all SDI levels.…”
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747
Data Sheet 1_China’s readiness for transitioning to a low-carbon economy: mitigant and catalyst factors for a geopolitical conflict.zip
Published 2025“…We use a qualitative analysis to identify that rising GPR, exacerbated by market instability, resource allocation conflicts, and trade disputes, significantly hinders LCED progress. However, these geopolitical tensions also act as a catalyst for accelerating the development of renewable energy, reducing reliance on traditional energy sources, and fostering low-carbon technologies. …”
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748
Image 1_Uptake of iron from ferrous fumarate can be mediated by clathrin-dependent endocytosis in Hutu-80 cells.tiff
Published 2025“…Iron uptake (ferritin L) from ferrous fumarate (0.5 mM, 24 h) in DMT1 silenced cells was significantly decreased (60% ± 11%) in comparison to iron controls while a 1-h dose of ferrous fumarate (0.5 mM) significantly decreased ferritin L formation in the presence of the clathrin inhibitor chlorpromazine (61% ± 10%, in post-confluent cells and 37% ± 9% in non-confluent cells). …”
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749
Table 1_Uptake of iron from ferrous fumarate can be mediated by clathrin-dependent endocytosis in Hutu-80 cells.docx
Published 2025“…Iron uptake (ferritin L) from ferrous fumarate (0.5 mM, 24 h) in DMT1 silenced cells was significantly decreased (60% ± 11%) in comparison to iron controls while a 1-h dose of ferrous fumarate (0.5 mM) significantly decreased ferritin L formation in the presence of the clathrin inhibitor chlorpromazine (61% ± 10%, in post-confluent cells and 37% ± 9% in non-confluent cells). …”
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750
Glial 5-HT<sub>2a</sub> receptors are necessary and rate limiting for experience-dependent synaptic glomeruli pruning.
Published 2024“…The Or42a OSN innervation volume with glial <i>5-HT</i><sub><i>2A</i></sub><i>R</i> OE is very significantly decreased in comparison to the control EB condition (<i>p</i> = 4.64 × 10<sup>−10</sup>). …”
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751
<b>Tracking incidence classification changes across disturbances at Konza Prairie LTER</b>
Published 2025“…Plants had the most populations classified as directed change (increasing=241/253, decreasing=95/101). The grazing press disturbance hypothesis was partially supported for plant taxa, which significantly differed by watershed treatments (Chi-square, p=3.182e-11). …”
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752
Table 1_Socioeconomic status and motor coordination function among children with autism.docx
Published 2025“…Mothers without a college degree showed a decreased likelihood of probable DCD (OR: 0.33, 95%CI: 0.15-0.71).…”
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753
<b>Sampling strategies and mitigation of natural and anthropogenic effects in detrital zircon provenance analysis of fluvial strata</b>
Published 2024“…The results from our study show that (1) the inflow of lower-order streams has a meaningful impact on the provenance signal of higher-order channels, but the impact distances are quite limited. (2) Lakes have significant hydraulic sorting effects on different-sized particles, and thus, complicate provenance signals, but trapping of zircon by lakes might be more limited. (3) The construction of dams would have a limited long-term impact on the detrital zircon provenance of rivers downstream if sediment could be discharged from the sediment pathway through the dam. (4) Anthropogenic erosion creates provenance signal enrichments of more easily eroded strata and can interfere with natural sediment sourcing. …”
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754
Deep reinforcement learning agents trained using a curriculum solve navigation tasks with delayed rewards.
Published 2025“…The agent is required to navigate towards a source which emits Poisson-distributed cues whose detection probability decreases with distance from the source (colored in green on a log scale). …”
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755
Data Sheet 1_Predicting climate change impacts on distribution and conservation of critically endangered Picea neoveitchii using MaxEnt.docx
Published 2024“…Under SSP2-4.5, SSP5-5.8 scenario, the suitable area decreases in all periods. Under SSP1-2.6 scenario, the suitable area decreases, except the period from 2080 to 2,100, which sightly increases. …”
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756
Highly efficient organic solar cells enabled by suppressing triplet exciton formation and non-radiative recombination
Published 2024“…The formation of triplet exciton is thought to be the main source of the large non-radiative energy loss. Decreasing the rate of back charge transfer is considered as an effective approach to alleviate the relaxation of the charge-transfer state and the triplet exciton generation. …”
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757
Short-Term Effects of Dark Chocolate on Choroidal Parameters in Myopic Patients During Near Work
Published 2025“…Both experiments found that the choroidal blood flow decreased significantly after near work, but the ChT decreased significantly only after consumption of dark chocolate. …”
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758
Supplementary file 1_The efficacy of resveratrol in the treatment of liver fibrosis: a systematic review and meta-analysis of preclinical studies.docx
Published 2025“…Objective<p>To evaluate the effects and underlying mechanisms of resveratrol—a plant-derived polyphenol abundantly found in natural dietary sources such as grapes and blueberries—on the amelioration of liver fibrosis.…”
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759
Rising mercury consumption from blue foods in China balanced by a shift to lower-mercury choices
Published 2025“…<table><tr><td><p dir="ltr">Blue foods pose significant health risks as a primary dietary source of total mercury (THg) exposure for humans. …”
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760
Analytic framework.
Published 2025“…</p><p>Results</p><p>Logistic regression analysis revealed a strong negative association where household income increases and indoor air pollution-related mortality significantly decreases. Specifically, Households in the highest income quartile showed a 22% reduction progressively in the odds of mortality risk compared to the lowest income quintile. …”