يعرض 1,121 - 1,140 نتائج من 1,434 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant substantial decrease ))~', وقت الاستعلام: 0.39s تنقيح النتائج
  1. 1121

    Table 1_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.docx حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"
  2. 1122

    Table 2_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf حسب Ying Xiao (6517)

    منشور في 2025
    "…Background<p>Pediatric infective endocarditis (IE) remains a rare but life-threatening condition, with substantial morbidity and mortality among children worldwide. …"
  3. 1123

    Table 1_Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retrospective cohort study.docx حسب Khalaf Kridin (7523390)

    منشور في 2025
    "…Introduction<p>Chronic, non-communicable inflammatory diseases (CIDs) affect a large portion of the population, imposing a significant morbidity, encompassing a substantial mortality. …"
  4. 1124

    Image 2_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.tif حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"
  5. 1125

    Table 1_Global burden and future trends of gastric cancer in women of reproductive age: estimates from the GBD 2021 Study, 1990–2050.xlsx حسب Nan Jiang (21252)

    منشور في 2025
    "…Although incidence is higher in men, GC remains a significant health issue for women of reproductive age (15–49 years) due to biological, hormonal, and socioeconomic factors. …"
  6. 1126
  7. 1127

    Data Sheet 2_Divergent trends and regional disparities in PM2.5 and O3 health economic burdens in China, 2013–2023: an integrated assessment with policy implications.zip حسب Ziqi Tang (10904159)

    منشور في 2025
    "…Results indicate a substantial decline in PM<sub>2.5</sub>-attributable mortality over the study period. …"
  8. 1128

    Data Sheet 5_CD44 knockdown alters miRNA expression and their target genes in colon cancer.zip حسب Diana Maltseva (11678641)

    منشور في 2025
    "…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …"
  9. 1129

    Table 3_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"
  10. 1130

    Table 2_Global burden and future trends of gastric cancer in women of reproductive age: estimates from the GBD 2021 Study, 1990–2050.xlsx حسب Nan Jiang (21252)

    منشور في 2025
    "…Although incidence is higher in men, GC remains a significant health issue for women of reproductive age (15–49 years) due to biological, hormonal, and socioeconomic factors. …"
  11. 1131

    Table 2_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.docx حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"
  12. 1132

    Image 1_Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retrospective cohort study.jpeg حسب Khalaf Kridin (7523390)

    منشور في 2025
    "…Introduction<p>Chronic, non-communicable inflammatory diseases (CIDs) affect a large portion of the population, imposing a significant morbidity, encompassing a substantial mortality. …"
  13. 1133

    Supplementary file 1_Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.docx حسب Omar Z. Ameer (8900039)

    منشور في 2025
    "…Clinical trials have demonstrated significant reductions in asthma exacerbation rates, improvements in forced expiratory volume in one second (FEV<sub>1</sub>), and decreased oral corticosteroid (OCS) dependence in adults and children with moderate-to-severe asthma. …"
  14. 1134

    Pathogenicity and transmissibility differences in goose-originated subgenotype 3 duck Tembusu virus in goose embryos and 3-day-old goslings حسب Ziqiao Zhao (18785775)

    منشور في 2024
    "…In the autumn of 2022, an outbreak of an infectious disease resembling DTMUV was reported in Guangdong Province, China, which caused significantly high mortality in goose embryos, and decreased egg production. …"
  15. 1135

    Data Sheet 1_Divergent trends and regional disparities in PM2.5 and O3 health economic burdens in China, 2013–2023: an integrated assessment with policy implications.zip حسب Ziqi Tang (10904159)

    منشور في 2025
    "…Results indicate a substantial decline in PM<sub>2.5</sub>-attributable mortality over the study period. …"
  16. 1136

    Table 7_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"
  17. 1137

    LncRNA MCM3AP-AS1 protects against cerebral ischemia-reperfusion injury via targeting miR-27b-3p حسب Rouli Dai (17063211)

    منشور في 2025
    "…<p>Cerebral ischemia-reperfusion (CI/R) injury is a significant hurdle in ischemic stroke treatment. Substantial evidence indicates that long non-coding RNAs (lncRNAs) are implicated in CI/R injury. …"
  18. 1138

    Data Sheet 1_Post-COVID syndrome patients show reduced anti-Spike antibodies compared to COVID-recovered controls, but enhanced IgG4/IgG1 switch after the third vaccine dose.pdf حسب Nineth Rossi (22355524)

    منشور في 2025
    "…Introduction<p>Long COVID and post-COVID syndromes represent a significant global health crisis and a substantial societal challenge. …"
  19. 1139

    Data Sheet 1_Global, regional, and national burdens of endometriosis from 1990 to 2021: a trend analysis.docx حسب Hailan Yan (18174379)

    منشور في 2025
    "…Background<p>Endometriosis is a common, chronic, estrogen-dependent gynecological disorder that significantly affects patients’ quality of life. However, the disease burden and its trends may be undergoing significant changes, and comprehensive data on this issue are currently lacking. …"
  20. 1140

    Table 1_Global, regional, and national disease burden and economic costs of cervical cancer (1991–2021): a multidimensional data synthesis analysis.docx حسب Yidi Ma (9507153)

    منشور في 2025
    "…Objectives<p>Cervical cancer remains a significant global health concern, particularly in less developed regions. …"