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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant threat » significant effect (Expand Search), significant increase (Expand Search)
threat decrease » greater decrease (Expand Search), largest decrease (Expand Search)
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281
Rinderine suppresses African swine fever virus replication in porcine alveolar macrophages by dual targeting of membrane-associated profilin 1 and phosphatidylethanolamine
Published 2025“…<p>African swine fever (ASF) is a highly contagious disease caused by African swine fever virus (ASFV), posing a serious threat to the global pig industry. Natural small molecules have been reported to exhibit anti-ASFV potential. …”
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282
Image 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.jpeg
Published 2025“…Background<p>The development of prostate cancer (PCa) remains a major health threat for men worldwide. Calcium/Calmodulin signaling pathway has been implicated to the initiation and progression of diverse human cancers. …”
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283
Table 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
Published 2025“…Background<p>The development of prostate cancer (PCa) remains a major health threat for men worldwide. Calcium/Calmodulin signaling pathway has been implicated to the initiation and progression of diverse human cancers. …”
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284
Table 2_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
Published 2025“…Background<p>The development of prostate cancer (PCa) remains a major health threat for men worldwide. Calcium/Calmodulin signaling pathway has been implicated to the initiation and progression of diverse human cancers. …”
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285
Table 3_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
Published 2025“…Background<p>The development of prostate cancer (PCa) remains a major health threat for men worldwide. Calcium/Calmodulin signaling pathway has been implicated to the initiation and progression of diverse human cancers. …”
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286
Table 1_RfaH contributes to maximal colonization and full virulence of hypervirulent Klebsiella pneumoniae.docx
Published 2024“…We found that the ΔrfaH mutant led to a significantly decreased mortality of K. pneumoniae in a mouse intraperitoneal infection model. …”
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287
Data_Sheet_1_Liver cirrhosis is a risk-factor for Pneumocystis jirovecii associated mortality.pdf
Published 2024“…Background<p>Pneumocystis jirovecci pneumonia (PCP) is a life threating disease in immunodeficient patients. Liver cirrhosis itself can lead to immunodefiency, however little is known if Pneumocystis jirovecci infection affects the outcome of patients with liver cirrhosis.…”
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288
Data Sheet 1_Phyllosphere microbiome responses to nano-berberine and chemical fungicides in powdery mildew infected strawberry.pdf
Published 2025“…The results showed that nano-fungicide application significantly reduced the disease index of powdery mildew and markedly decreased its incidence in field-grown strawberries, ultimately lowering leaf disease incidence to 5.06% with a control efficacy of 96.81%. …”
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289
Table 1_Global burden of pneumoconiosis from 1990 to 2021: a comprehensive analysis of incidence, mortality, and socio-demographic inequalities in 204 countries and territories.doc...
Published 2025“…Background<p>Pneumoconiosis, a group of occupational lung diseases caused by prolonged inhalation of mineral dust, remains a critical global health threat due to persistent workplace exposures in high-risk industries such as mining, construction, and artificial stone processing. …”
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290
Table 1_Molecular, biofilm and motility characterization of Acinetobacter baumannii isolated from a neonatal intensive care unit at a children’s hospital in South China.xlsx
Published 2025“…Background<p>Multidrug-resistant Acinetobacter baumannii (MDR-AB) poses a critical threat in neonatal intensive care units (NICUs), however few studies have reported the molecular characterization of A. baumannii isolates from the NICU in China. …”
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291
Table 1_Projecting global shifts in the invasive potential of Bidens pilosa L. under climate change using species distribution models.xlsx
Published 2025“…<p>Invasive species pose significant threats to ecosystems by reducing biodiversity, introducing new diseases, and competing with native species for resources. …”
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292
Supplementary file 1_Tapered fiber probe-based optical cardiac pacemaker.docx
Published 2025“…Introduction<p>The disorders of cardiac rhythm usually induce severe cardiovascular pathologies which might pose significant threats to human health. Although multiple cardiac pacing modalities have been developed, most of them face potential limitations including structural complexity, spatiotemporal imprecision and invasive implantation requirements, thereby constraining their widespread biomedical applications.…”
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293
Table 1_Association between social phobia and allergic asthma in adolescents.docx
Published 2025“…Background<p>Social phobia and asthma pose threats to the health of adolescents at the psychological and physical levels, respectively. …”
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294
Supplementary file 1_The effects of vessel speed and size on the lethality of strikes of large whales in U.S. waters.xlsx
Published 2025“…Humpback whales (Megaptera novaeangliae) had significantly lower rates of lethal strikes compared to other large whales. …”
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295
Supplementary file 2_The effects of vessel speed and size on the lethality of strikes of large whales in U.S. waters.docx
Published 2025“…Humpback whales (Megaptera novaeangliae) had significantly lower rates of lethal strikes compared to other large whales. …”
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296
Table1_Trp-574-Leu and the novel Pro-197-His/Leu mutations contribute to penoxsulam resistance in Echinochloa crus-galli (L.) P. Beauv..docx
Published 2024“…In vitro ALS activity assays demonstrated a significantly higher activity in AH-R compared to the susceptible population (YN-S). …”
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297
Supplementary file 1_Transcriptome-wide N6-methyladenosinem modifications analysis of chicken cecum in responding to Campylobacter jejuni inoculation.zip
Published 2025“…</p>Results<p>In the S group, the level of proinflammatory cytokines (IL-8, IL-1β, IL-18, TNF-α, IL-17A) and global RNA methylation were significantly decreased (P < 0.05). A total of 30,427 and 30,367 m<sup>6</sup>A peaks were identified in R and S groups, which were primarily located in 3'UTR and CDS regions. …”
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298
ERICC Policy Brief_ Supporting children’s mental health and wellbeing in and through education in contexts of conflict and protracted crises
Published 2025“…These threats contribute to depression, anxiety and post-traumatic stress disorder (Tol et al., 2013), potentially decreasing attendance and retention rates as well as learning quality and continuity. …”
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299
Table 1_High humidity environment increases FBG by impairing the intestinal barrier.xlsx
Published 2025“…Introduction<p>Climate and environmental changes pose significant threats to human metabolic health; however, the specific effects of individual environmental factors on metabolic diseases remain poorly understood. …”
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300
Table 2_High humidity environment increases FBG by impairing the intestinal barrier.docx
Published 2025“…Introduction<p>Climate and environmental changes pose significant threats to human metabolic health; however, the specific effects of individual environmental factors on metabolic diseases remain poorly understood. …”