يعرض 18,461 - 18,480 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant time decrease ))', وقت الاستعلام: 0.54s تنقيح النتائج
  1. 18461
  2. 18462

    Table1_Adverse event signal mining and severe adverse event influencing factor analysis of Lumateperone based on FAERS database.docx حسب Yanjing Zhang (401134)

    منشور في 2024
    "…Conversely, concomitant use of CYP3A4 inhibitors or drugs metabolized by CYP3A4 was associated with a decreased risk of severe AEs (OR = 0.524 [0.434, 0.633], P = 0.000).…"
  3. 18463

    Table11_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx حسب Yifang He (18126257)

    منشور في 2024
    "…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…"
  4. 18464

    Data Sheet 1_Cross-species analysis of FcγRIIa/b (CD32a/b) polymorphisms at position 131: structural and functional insights into the mechanism of IgG- mediated phagocytosis in hum... حسب William D. Tolbert (7870697)

    منشور في 2025
    "…In contrast, allele-specific effects in macaques were highly significant; the macaque P<sup>131</sup> variant showing uniformly reduced IgG affinity. …"
  5. 18465

    Table 1_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.docx حسب Leqing Zhou (20981021)

    منشور في 2025
    "…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m<sup>2</sup>, while it decreased by 11.4ml/min/1.73 m<sup>2</sup> in the RNU group (WMD, 11.81 ml/min/1.73 m<sup>2</sup>; 95%CI,9.06-14.56; P<0.0001).…"
  6. 18466
  7. 18467

    Table 1_The knowledge paradox: an inverted U-shaped association between HIV knowledge and stigma among older men in Sichuan Province, Southwest China.docx حسب Zhihua Ye (3133311)

    منشور في 2025
    "…Background<p>Older men (≥50 years) in China face elevated HIV infection risks, yet HIV stigma remains a significant barrier to prevention. Although HIV knowledge is frequently assumed to reduce stigma, the evidence is inconsistent. …"
  8. 18468

    Data Sheet 1_Metformin upregulates circadian gene PER2 to inhibit growth and enhance the sensitivity of glioblastoma cell lines to radiotherapy via SIRT2/G6PD pathway.docx حسب Hailiang Li (740080)

    منشور في 2025
    "…Meanwhile, NADPH+ production and G6PDH enzyme activity significantly decreased. Further study validated that metformin inhibited the cell growth of GBM cell lines through up-regulating PER2 and inhibited SIRT2/G6PD signaling pathway, enhancing radiotherapy(RT) sensitivity. …"
  9. 18469

    Table8_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx حسب Yifang He (18126257)

    منشور في 2024
    "…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…"
  10. 18470
  11. 18471

    Table5_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx حسب Yifang He (18126257)

    منشور في 2024
    "…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…"
  12. 18472

    DataSheet1_Probiotics combined with prebiotics alleviated seasonal allergic rhinitis by altering the composition and metabolic function of intestinal microbiota: a prospective, ran... حسب Yangfan Hou (8043884)

    منشور في 2024
    "…From baseline to day 91, mean difference between groups (MDBG) in the reduction of TNSS was -1.1 (-2.2, -0.1) (P = 0.04); MDBG in the increment of TNF-α was 7.1 pg/ml (95% CI: 0.8, 13.4, P = 0.03); the INF-γ level was significantly increased (P = 0.01), whereas that of IL-17 (P = 0.005) was significantly decreased in the test group, whilst mean difference within groups was not statistically significant in the placebo group; MDBG in the increment of acetate was 12.4% (95% CI: 7.1%, 17.6%, P <0.001). …"
  13. 18473

    Experimental protocol and behavioral evidence of perceptual learning. حسب Sarit F.A. Szpiro (21094755)

    منشور في 2025
    "…The shaded area represents the standard error of the mean. Significant clusters for the main effect of PRE/post training, as determined by cluster mass permutation two-tailed tests, are indicated with rectangles (p < 0.05 and p < 0.1). …"
  14. 18474

    Data Sheet 2_Cellular effects of splenectomy on liver regeneration after 70% resection.pdf حسب Andrey Elchaninov (3122742)

    منشور في 2025
    "…Splenectomy also correlated with decreased rates of Ly6C+ monocyte and Ly6G+ leukocyte migration. …"
  15. 18475

    Genetic and structural factors contributing to the dominance and persistence of goose astrovirus type 2 حسب Peng Jiang (16544)

    منشور في 2025
    "…<p>Goose astrovirus (GoAstV) has emerged as a significant pathogen affecting the goose industry in China, with GoAstV-2 becoming the dominant genotype since 2017. …"
  16. 18476
  17. 18477

    Glucagon-like peptide 1 receptor agonists modestly reduced low-density lipoprotein cholesterol and total cholesterol levels independent of weight reduction: a meta-analysis and met... حسب Frederick Berro Rivera (12679463)

    منشور في 2024
    "…</p> <p>GLP-1RA treatment modestly decreased LDL-C and TC but did not significantly affect triglycerides, VLDL-C, or HDL-C.…"
  18. 18478

    Image 1_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff حسب Matthew C. Austin (20633168)

    منشور في 2025
    "…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …"
  19. 18479

    Data Sheet 1_Cellular effects of splenectomy on liver regeneration after 70% resection.pdf حسب Andrey Elchaninov (3122742)

    منشور في 2025
    "…Splenectomy also correlated with decreased rates of Ly6C+ monocyte and Ly6G+ leukocyte migration. …"
  20. 18480

    Image 1_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.tif حسب Leqing Zhou (20981021)

    منشور في 2025
    "…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m<sup>2</sup>, while it decreased by 11.4ml/min/1.73 m<sup>2</sup> in the RNU group (WMD, 11.81 ml/min/1.73 m<sup>2</sup>; 95%CI,9.06-14.56; P<0.0001).…"