يعرض 18,501 - 18,520 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant time decrease ))', وقت الاستعلام: 0.46s تنقيح النتائج
  1. 18501

    Image 2_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.tif حسب Leqing Zhou (20981021)

    منشور في 2025
    "…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m<sup>2</sup>, while it decreased by 11.4ml/min/1.73 m<sup>2</sup> in the RNU group (WMD, 11.81 ml/min/1.73 m<sup>2</sup>; 95%CI,9.06-14.56; P<0.0001).…"
  2. 18502

    Image 2_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff حسب Matthew C. Austin (20633168)

    منشور في 2025
    "…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …"
  3. 18503
  4. 18504

    Table 1_Optimal fertilizer rate and sowing density can improve oat quality, yield and N and P comprehensive efficiency in the Loess Plateau of China.docx حسب Ruochen Zhang (3434996)

    منشور في 2025
    "…The results of correlation analysis revealed significant positive correlations (P< 0.05) of forage yield and CP with nutrients efficiency of oat, but negative correlations with fiber content.…"
  5. 18505

    Data Sheet 1_Reducing enteric methane emission in dairy goats: impact of dietary inclusions of quebracho tannin extract on ruminal microbiota.pdf حسب Paola Cremonesi (5892311)

    منشور في 2025
    "…The overall fungal biodiversity was also significantly changed (P < 0.05); the fiber-degrading Liebetanzomyces decreased, while the tannin-degrading Aspergillus increased (P < 0.05). …"
  6. 18506

    Glucose and G-6-P levels modulate HK2-<i>SOX10</i> mRNA association and <i>SOX10</i> mRNA translation. حسب Ana Luisa Dian (22258504)

    منشور في 2025
    "…<p><b>(A)</b> Western blot analysis of HK2 and SOX10 protein level in A375 cells cultured for 24 h with decreasing concentrations of glucose or under glucose starvation, as indicated. …"
  7. 18507

    30-year trends in incidence of acute STEMI and NSTEMI in the Belgian Province of Luxembourg. A long-term follow-up of the MONICA-BELLUX registry حسب Bernhard L. Gerber (10171583)

    منشور في 2025
    "…</p><p>b) What this study adds</p><p>In a 30-year registry in Luxembourg using modern AMI definitions, overall, AMI incidence decreased significantly, primarily due to a 3.8-fold reduction in STEMI.…"
  8. 18508

    Data_Sheet_1_Association of systemic immune-inflammation index with malnutrition among Chinese hospitalized patients: a nationwide, multicenter, cross-sectional study.docx حسب Mengyuan Chen (5633153)

    منشور في 2024
    "…Both lower and higher SII levels (either continuous or categorical variable) were significantly associated with an increased risk of malnutrition.…"
  9. 18509

    Table 5_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx حسب Jianwei Hong (6918776)

    منشور في 2025
    "…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …"
  10. 18510

    Protein and gene expression levels of p62 and LC3B in miR-7974 mimic-transfected MCF-7 cells. حسب Stralina Eneh (21213312)

    منشور في 2025
    "…<b>(D)</b> The gene expression level of <i>LC3B</i> was decreased and <b>(E)</b> expression level of <i>p62</i> upregulated in miR-7974-treated MCF-7 cells. …"
  11. 18511

    Data Sheet 1_Andrographolide suppresses chondrosarcoma cell migration and invasion by inhibiting the PI3K/Akt/mTOR signaling pathway and activating autophagy.pdf حسب Chun-Fei Wu (22315444)

    منشور في 2025
    "…Confocal microscopy demonstrated a significant increase in autophagic flux in Andro-treated SW1353 cells. …"
  12. 18512

    Table 1_Danggui Buxue Decoction attenuates 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone—induced lung cancer growth in A/J mice by suppressing HIF-1α/VEGF-mediated angiogenesis.do... حسب Wu Chen (569414)

    منشور في 2025
    "…By week 20, progressive multifocal opacities emerged alongside reduced pulmonary artery flow, impaired lung function, elevated TNF-α/VEGF, and decreased WBC, lymphocytes, and platelets. Compared to untreated controls, 10-week DBD treatment significantly suppressed lung tumor growth, reduced lesion microvessel density, downregulated HIF-1α and VEGF expression, and ameliorated hematological dysregulation.…"
  13. 18513

    Table 1_Effect of compound kushen injection on immune function in patients with colorectal cancer: a systematic review and meta-analysis.docx حسب Lixin Zhang (55947)

    منشور في 2025
    "…Chemotherapy and radiotherapy remain cornerstone treatments; however, they often lead to significant immune suppression and an increased risk of infection. …"
  14. 18514

    Uncovering the mechanistic basis of <i>Rheum palmatum</i> L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular doc... حسب Wenjing He (4278625)

    منشور في 2025
    "…MR analysis demonstrated a statistically significant causal association between TNF and CKD (OR = 1.02, <i>p</i> < 0.05), with positive trends for IL6 and CASP3. …"
  15. 18515

    Image 2_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg حسب Johnny Amer (495285)

    منشور في 2025
    "…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …"
  16. 18516

    Repetitive stress modulates loudness perception. حسب Ghattas Bisharat (20706928)

    منشور في 2025
    "…Mice exhibited increased perceptual boundaries during repeated stress, indicating a decreased loudness perception (<i>t</i> test, <i>p</i> = 1.2 × 10<sup>−05</sup>, mean ± SE). …"
  17. 18517

    Image 3_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg حسب Johnny Amer (495285)

    منشور في 2025
    "…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …"
  18. 18518

    Table 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.docx حسب Johnny Amer (495285)

    منشور في 2025
    "…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …"
  19. 18519

    Table 1_Studies on fatty acids and microbiota characterization of the gastrointestinal tract of Tianzhu white yaks.docx حسب Chen Shaopeng (20576303)

    منشور في 2025
    "…Introduction<p>The gut microbiota significantly influences the host’s production performance and health status, with different gastrointestinal tissues exhibiting functional diversity reflected in their microbial diversity.…"
  20. 18520

    Data Sheet 1_CD226+ B cells in primary Sjögren’s syndrome: a key player in clinical manifestations and disease pathogenesis.docx حسب Ping Zhao (47228)

    منشور في 2025
    "…</p>Results<p>CD226 expression in the peripheral blood of pSS patients was significantly increased on T cells, CD19<sup>+</sup> B cells and CD14<sup>+</sup> monocytes, but significantly decreased on CD56<sup>+</sup> NK cells.We identified a distinct CD226<sup>+</sup>CD19<sup>+</sup> B cell subset that exhibited pathogenic features in pSS. …"