Image 1_The inhibitory effects of 7ND protein on osteoclast differentiation in apical periodontitis.tif حسب Zhang-Zhang Ji (21611168)

"…In AP rats treated with 7ND protein, X-ray imaging and micro-computed tomography demonstrated a significant decrease in lesion volume and area in the periapical regions compared to AP rats treated with PBS.…"

Supplementary Material for: NANLING: Roxadustat effectiveness/safety in chronic kidney disease-associated anemia with peritoneal dialysis حسب figshare admin karger (2628495)

"…The change in Total FACT-An score (baseline to Week 24), but not SF-36 scores, was clinically significant (−6.2 [−9.0, −3.4]), with a greater decrease in the T2DM subgroup. …"

Video 3_Case Report: Allogeneic adipose-derived mesenchymal stem cells for severe feline chronic kidney disease.mp4 حسب Yizhe Song (11859734)

"…Concurrently, laboratory results revealed a decrease in key renal biomarkers (SCr, BUN, and P) and an amelioration of the non-regenerative anemia. …"

Table 8_Analysis of global, regional, and national burdens of neonatal encephalopathy from 1990 to 2021: insights from the Global Burden of Disease Study 2021.doc حسب Shujun Tan (20011518)

"…</p>Results<p>The global burden of NE has significantly declined over the past three decades. Between 1990 and 2021, the global ASIR decreased from 20.22 to 17.16, while the number of cases fell from 1,295,891.1 to 1,061,448.15, reflecting an 18.09% reduction. …"

Image 1_Burden of falls in China, 1992–2021 and projections to 2030: a systematic analysis for the global burden of disease study 2021.pdf حسب Liang Sui (20912441)

"…DALYs and years of life lost (YLLs) rates generally decreased, with intervals of stabilization and minor increases, while years lived with disability (YLDs) showed significant fluctuations. …"

DataSheet1_Feasibility exploration of GSH in the treatment of acute hepatic encephalopathy from the aspects of pharmacokinetics, pharmacodynamics, and mechanism.DOCX حسب Kangrui Hu (18718429)

"…Pharmacokinetic studies suggested that AHE modeling led to significant decrease in hepatic and cerebral exposure of GSH and cysteine. …"

Image 4_Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses.tif حسب Sielke Caestecker (20749481)

"…</p>Results<p>In a significant number of rats (7/15) we found an increase in hippocampal NA release, field excitatory post synaptic potential (fEPSP) slope and population spike (PS) amplitude, indicating an increase in excitatory neurotransmission and neuronal output. 4/15 rats showed a decrease in NA release without changes in fEPSP slope or PS amplitude, and 4/15 showed no change in NA release.…"

Image2_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.tif حسب Bing Cui (179696)

"…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …"

Table 1_The inhibitory effects of 7ND protein on osteoclast differentiation in apical periodontitis.xlsx حسب Zhang-Zhang Ji (21611168)

"…In AP rats treated with 7ND protein, X-ray imaging and micro-computed tomography demonstrated a significant decrease in lesion volume and area in the periapical regions compared to AP rats treated with PBS.…"

Image_2_Effects of tree species identity on soil microbial communities in Juglans nigra and Quercus rubra plantations.TIFF حسب Juan P. Frene (12227753)

"…Conversely, Q. rubra tends to decrease these indices. Significant disparities in microbial composition between the two tree species were evident, with J. nigra exhibiting enrichment in certain taxa such as Nitrospira, Geobacter, and Bacillus while Q. rubra showed enrichment in others like Acidobacteriota and ectomycorrhizal fungi. …"

Data Sheet 2_Efficacy and safety of hydroxyurea therapy on patients with β-thalassemia: a systematic review and meta-analysis.pdf حسب Tianmin Huang (20561477)

"…HU, in transfusion-dependent β-thalassemia patients, was related to a significant decrease in transfusion requirements [a pooled RR of 0.37 and a pooled good RR of 0.65 (95% CI, 0.53–0.76)]; in transfusion-independent β-thalassemia patients, it was correlated to an excellent raise in Hb levels [a pooled RR of 0.20 (95% CI, 0.08–0.35) and a pooled good RR of 0.53 (95% CI, 0.41–0.65)]. …"

Image 3_Pronounced impairment of B cell differentiation during bone regeneration in adult immune experienced mice.tiff حسب Mireille Ngokingha Tchouto (20812811)

"…</p>Results<p>While the B cell proportion in young and non-immune experienced animals did not significantly change from 2 to 5 days post osteotomy in the hematoma, we found a significant decrease of the B cell proportion in the immune experienced mice, which was accompanied by the decreased expression of B cell specific genes, suggesting a specific response in immune experienced animals. …"

Table 1_Hesperidin alleviates hypothyroidism-related cardiac dysfunction by targeting cardiac miRNAs, Nrf2/NF-κB signaling, oxidative stress and inflammation.docx حسب Asmaa M. Gaber (21640814)

"…</p>Results<p>CMZ intake resulted in a significant decrease in thyroid hormones (THs) levels with a subsequent increase in serum thyroid stimulating hormone and cardiac enzymes activities, dyslipidemia, and body weight gain. …"

Data Sheet 1_miR-198 targets TOPORS: implications for oral squamous cell carcinoma pathogenesis.pdf حسب Pankhuri Kaushik (20381022)

"…Delivery of a synthetic miR-198 mimic to OSCC cells results in a significant decrease in xenograft size in nude mice, potentiating its use in therapeutics.…"

Image 3_Identification of immune subtypes associated with CD8+ T cell-related genes providing new treatment strategies of esophageal carcinoma.pdf حسب Youyi Wu (20786402)

"…</p>Results<p>The results revealed significant correlations between CD8+ T cell-related genes and immune-related pathways. …"

Image 1_Global patterns and health impact of unintentional injuries among children and adolescents, 1990–2021.tif حسب Wei Wei (21173)

"…Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. Regionally, from 1990 to 2021, the Caribbean experienced the largest relative increase in injury incidence (EAPC 0.25, 95% CI: −0.60 to 1.11). …"

Table_3_Proteomics fingerprinting reveals importance of iron and oxidative stress in Streptomyces scabies–Solanum tuberosum interactions.docx حسب Lauriane Giroux (19779051)

"…The increase in the abundance of proteins related to pyochelin biosynthesis was consistent with a significant decrease in the iron content in the culture medium, as well as with induction of expression of pyochelin biosynthesis genes. …"

Data_Sheet_1_Effects of tree species identity on soil microbial communities in Juglans nigra and Quercus rubra plantations.xlsx حسب Juan P. Frene (12227753)

"…Conversely, Q. rubra tends to decrease these indices. Significant disparities in microbial composition between the two tree species were evident, with J. nigra exhibiting enrichment in certain taxa such as Nitrospira, Geobacter, and Bacillus while Q. rubra showed enrichment in others like Acidobacteriota and ectomycorrhizal fungi. …"

FCM analysis (%). حسب Takanori Kitagawa (20727226)

"…YCW-H demonstrated significant anti-proliferative effects on MCF7 cells, reducing cell growth by 58.7% ± 6.9 even when physically separated from the cells by a plastic wall. …"

Image 1_Alteration of vasopressin-aquaporin system in hindlimb unloading mice.tif حسب Marianna Ranieri (330759)

"…Conversely, in 4 weeks HU suspended mice, copeptin decreased significantly and both AQP2 mRNA and AQP2 total protein expression were significantly reduced. …"