MiR-15a-5p Knockdown up-Regulated ABCB1 Expression and Abated HNSCC Progression via the NF-κB Signaling Pathway by Jing Liu (38537)

“…</p> <p>ATP binding cassette transporter 1 (ABCB1) had the highest mutation frequency and multiple mutation types in HNSCC, and the decreased ABCB1 was significantly related to better prognosis of HNSCC patients. …”

Table 1_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”

Table 2_Global, regional and national burden of traumatic amputations from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.docx by Baixing Wei (21461966)

“…However, the change in age-standardized rates from 1990 to 2021 declined significantly. The association between the Socio-demographic Index (SDI) and the burden of amputations in 2021 was not linear. …”

Table2_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx by Eryun Zhang (20172057)

“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”

Interplay of <i>Mycobacterium abscessus</i> and <i>Pseudomonas aeruginosa</i> in experimental models of coinfection: Biofilm dynamics and host immune response by Víctor Campo-Pérez (21267009)

“…Coinfections in bronchial epithelial cells significantly decreased cell viability, whereas in <i>G. mellonella</i>, coinfections induced lower survival rates than individual infections. …”

Image 2_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff by Emmrich Wakeford (21249104)

“…Consequently, the number of viral genome copies or viral titers were also significantly decreased in the YFP-Ubiquitin_K48R cells compared to the YFP-Ubiquitin_WT cells. …”

Data Sheet 1_Cerebrospinal fluid and serum cytokine profiles in severe viral encephalitis with implications for refractory status epilepticus: a retrospective observational study.d... by Peipei Huang (3623933)

“…CSF IL-6 and IL-8 levels were significantly elevated in the RSE group compared to patients without seizures and with controlled seizures, decreasing gradually and independently of serum cytokine levels. …”

Molecular characterization of zinc metalloproteinase Nas-14 from Trichinella spiralis and its participation in intestinal invasion by Qingbo Lv (21676001)

“…In addition, the direct incubation of rTsNas14 with claduin-1 showed that rTsNas14 could significantly degrade claudin-1. In vivo studies have demonstrated that inhibition of TsNas14 expression significantly impairs the infectivity of T. spiralis in mice, resulting in a decreased AW and muscle larval burden. …”

Data Sheet 1_Association between the systemic immune-inflammatory index and the immune response after hepatitis B vaccination: a cross-sectional analysis of NHANES data.docx by Jiayan Hu (18593615)

“…Notably, antibody expression significantly decreased as the SII increased beyond the threshold of 448.3.…”

Table 5_Global, regional and national burden of traumatic amputations from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.docx by Baixing Wei (21461966)

“…However, the change in age-standardized rates from 1990 to 2021 declined significantly. The association between the Socio-demographic Index (SDI) and the burden of amputations in 2021 was not linear. …”

Table 3_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”

Table4_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx by Eryun Zhang (20172057)

“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”

Image 1_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif by Houle Guo (21264647)

“…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …”

Table 3_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.xl... by Junhyeok Choi (14078586)

“…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …”

Image 1_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff by Emmrich Wakeford (21249104)

“…Consequently, the number of viral genome copies or viral titers were also significantly decreased in the YFP-Ubiquitin_K48R cells compared to the YFP-Ubiquitin_WT cells. …”

Table 2_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”

Fasting inhibits glycolysis and migration/invasion in gallbladder cancer via PCBP2/ANGPTL4 signaling by Ying Tao (469347)

“…We found that fasting could inhibit glycolysis and cell migration/invasion in GBC cells and that fasting mimic diets could significantly inhibit GBC cell proliferation in a mouse xenograft model. …”

Data Sheet 1_Effect of NR1D1 on the proliferation and differentiation of yak skeletal muscle satellite cells.pdf by Yuqi Zhe (20107152)

“…Compared with those in the control group, the expression levels of proliferation marker genes KI-67, CYCLIND1, and CYCLINA were significantly inhibited after NR1D1 overexpression, which was also supported by the CCK-8 test, whereas differentiation marker genes MYOD, MYOG, and MYF5 were significantly inhibited. …”

Table3_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx by Eryun Zhang (20172057)

“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”

Global maximum GPP from 2001-2018 by Xu (7493744)

“…The GPPmax estimates from this study and the changes in their trends were highly correlated with GPPmax estimates from the vegetation photosynthesis model, with R2 > 0.70 for most vegetation types. The GPPmax significantly increased in western North America, northern Europe, and eastern China, but decreased in tropical regions. …”