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significant treatment » significant investment (Expand Search), significant enrichment (Expand Search), significant impairment (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
treatment decrease » treatment decreased (Expand Search), treatments decreased (Expand Search), treatment increases (Expand Search)
significant treatment » significant investment (Expand Search), significant enrichment (Expand Search), significant impairment (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
treatment decrease » treatment decreased (Expand Search), treatments decreased (Expand Search), treatment increases (Expand Search)
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4201
Table 1_MIKC-type MADS-box transcription factor OsMADS31 positively regulates salinity tolerance in rice.xlsx
Published 2025“…At the three-leaf stage, knockout mutants showed significantly lower survival rates following salt treatment and subsequent recovery. …”
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4202
Image 2_Kaixin San Jiawei granule improves cognitive function and alleviates neuronal damage in Alzheimer’s disease via multi-component and multi-target mechanisms.tif
Published 2025“…Treatment increased hippocampal levels of ACh and GSH-Px while reducing AChE and ROS. …”
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4203
Numerical data and gene lists for all graphs.
Published 2025“…Furthermore, mapping H2A.Z incorporation before and after treatment with HU revealed that decreases in H2A.Z enrichment at transcription start sites was correlated with, but generally not required for, the upregulation of genes during HU exposure. …”
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4204
Video 4_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”
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4205
Table 1_Oral supplementation with Lactobacillus fermentum MC018 improves intestinal health, immune response, and growth performance of Zi geese infected with Escherichia coli XH197...
Published 2025“…Introduction<p>Escherichia coli infection causes severe diarrhea, decreases growth performance, and increases mortality of poultry, which imposes a significant economic burden on the poultry industry and severely limits its growth.…”
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4206
Data Sheet 1_Identification of potential biomarkers for lung adenocarcinoma: a study based on bioinformatics analysis combined with validation experiments.zip
Published 2024“…Meanwhile, TGFBR2 expression was decreased in LUAD group through immunohistochemistry. …”
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4207
Data Sheet 1_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx
Published 2025“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”
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4208
Image_1_Study of epirubicin sustained–release chemoablation in tumor suppression and tumor microenvironment remodeling.jpeg
Published 2025“…On day 4 after local injection of the EPI gel, the expression of PD-L1 in abscopal tumors was upregulated, while the expression of PD-L1 in bilateral tumors in mice was significantly reduced after anti-PD-L1 treatment. The proportion of CD3<sup>+</sup>CD8<sup>+</sup>PD-1<sup>+</sup> cells in the tumor and circulating blood in the EPI-GEL/PD-L1 group was decreased compared with that in the EPI-GEL (single injection of epirubicin) group.…”
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4209
Supplementary file 1_Shaoyao gancao decoction induces autophagy by modulating miR-21 and inhibiting the AKT/mTOR signaling pathway in adenomyosis-derived ectopic endometrial stroma...
Published 2025“…Results from cell experiments indicated that treatment with SGD downregulated miR-21 mRNA expression along with p-AKT and p-mTOR protein levels (P < 0.01), while up-regulating PTEN mRNA expression (P < 0.01) in EESCs. …”
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4210
DESeq output data for all comparisons.
Published 2025“…Furthermore, mapping H2A.Z incorporation before and after treatment with HU revealed that decreases in H2A.Z enrichment at transcription start sites was correlated with, but generally not required for, the upregulation of genes during HU exposure. …”
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4211
Supplementary file 2_Shaoyao gancao decoction induces autophagy by modulating miR-21 and inhibiting the AKT/mTOR signaling pathway in adenomyosis-derived ectopic endometrial stroma...
Published 2025“…Results from cell experiments indicated that treatment with SGD downregulated miR-21 mRNA expression along with p-AKT and p-mTOR protein levels (P < 0.01), while up-regulating PTEN mRNA expression (P < 0.01) in EESCs. …”
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4212
Data Sheet 2_LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis.docx
Published 2025“…Furthermore, a rat peri-implantitis model was established, and the degree of peri-implant tissue inflammation and bone loss was assessed using micro-CT scanning and immunohistochemistry after treatment with various macrophage supernatants.</p>Results<p>NRIR knockdown reduced RSAD2 expression and suppressed activation of the NF-κB pathway, consequently decreasing inflammatory cytokines and M1 macrophage-associated cytokine expression in THP-1 macrophages. …”
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4213
Data Sheet 1_Efficacy and safety of PCSK9 inhibitors, potent statins, and their combinations for reducing low-density lipoprotein cholesterol in hyperlipidemia patients: a systemat...
Published 2025“…Meanwhile, compared with placebo, evolocumab (MD −1.89, 95% CI −2.27 to −1.50), alirocumab (MD −1.83, 95% CI −2.09 to −1.57), rosuvastatin (MD −1.93, 95% CI −2.30 to −1.56), inclisiran (MD −1.68, 95% CI −2.10 to −1.27), and atorvastatin (MD −1.68, 95% CI −2.04 to −1.31) could also play a role in the treatment of LDL-C reduction. Moreover, the incidence of adverse events (AEs) was similar to that observed in the control group, which included both placebo and potent statin groups, with no significant differences identified in our study (P > 0.05).…”
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4214
Video 3_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”
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4215
Data Sheet 1_MIKC-type MADS-box transcription factor OsMADS31 positively regulates salinity tolerance in rice.pdf
Published 2025“…At the three-leaf stage, knockout mutants showed significantly lower survival rates following salt treatment and subsequent recovery. …”
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4216
Video 7_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”
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4217
DataSheet1_Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing.pdf
Published 2024“…Notably, CD8+ T cells were significantly increased and activated via Jak/Stat pathway in the AA model but inactivated after CXCL12 Ab treatment. …”
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4218
Table1_Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing.xlsx
Published 2024“…Notably, CD8+ T cells were significantly increased and activated via Jak/Stat pathway in the AA model but inactivated after CXCL12 Ab treatment. …”
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4219
Data Sheet 1_Clinical pharmacist interventions in medication review for medication optimization in older hospitalized adults with mental disorders and somatic comorbidities: eviden...
Published 2025“…Adherence to treatment guidelines for somatic comorbidities improved significantly (from 3.3%–13.2% to 50.0%–72.6%; p < 0.001).…”
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4220
Data Sheet 1_Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.xlsx
Published 2025“…Using inhibitors of PHB1 or transfecting N. caninum-infected THP-1 cells with PHB1 siRNA significantly decreased IL-1β production, but not TNF-α.…”