Data Sheet 1_α-Mangostin prevents diabetic cardiomyopathy by inhibiting oxidative damage and lipotoxicity through the AKT–FOXO1–CD36 pathway.pdf by Xue Bai (129175)

“…In diabetic mice, low-dose A-MG treatment increased anti-oxidative stress capacity, decreased myocardial lipid accumulation, reduced fibrosis and cardiomyocyte apoptosis, and improved left ventricular contractile function.…”

Table 1_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx by Oliver Küppers (22742732)

“…Treatment with 50 μg rTSG-6 significantly enhanced bone formation compared to untreated and low-dose (10 µg) controls at 35 days post-injury. …”

Table 1_Electroacupuncture improves scopolamine hydrobromide induced dry eye in mice via inhibiting ocular surface inflammation and regulating the HMGB1-related signaling pathways.... by Xia Wu (203682)

“…The levels of HMGB1, RAGE, TLR2, TLR4, and IL-6 were significantly decreased while IL-10 level was significantly increased after EA treatment, indicating that EA may improve dry eye surface inflammation by inhibiting HMGB1-related signaling pathways.…”

Table 2_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx by Oliver Küppers (22742732)

“…Treatment with 50 μg rTSG-6 significantly enhanced bone formation compared to untreated and low-dose (10 µg) controls at 35 days post-injury. …”

Data Sheet 1_TSG-6 promotes healing of critical-sized bone defects in mice.pdf by Oliver Küppers (22742732)

“…Treatment with 50 μg rTSG-6 significantly enhanced bone formation compared to untreated and low-dose (10 µg) controls at 35 days post-injury. …”

Table 3_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx by Oliver Küppers (22742732)

“…Treatment with 50 μg rTSG-6 significantly enhanced bone formation compared to untreated and low-dose (10 µg) controls at 35 days post-injury. …”

Data Sheet 2_TSG-6 promotes healing of critical-sized bone defects in mice.pdf by Oliver Küppers (22742732)

“…Treatment with 50 μg rTSG-6 significantly enhanced bone formation compared to untreated and low-dose (10 µg) controls at 35 days post-injury. …”

Table 1_Radiofrequency ablation vs. cryoablation for pediatric atrioventricular nodal reentrant tachycardia in the era of three-dimensional electroanatomical mapping.docx by Yao-Wei Chan (20639414)

“…Ablation outside the low Koch triangle and cryoablation were independently associated with longer procedure times. The procedure time decreased significantly in the recent 50% of RF ablation cases, but not in cryoablation cases.…”

DataSheet1_Dipeptide alanine-glutamine ameliorates retinal neurodegeneration in an STZ-induced rat model.docx by Yuhan Zhang (2792089)

“…Retinal levels of inflammatory factors were significantly decreased in Ala-Gln-treated diabetic rats. …”

Data Sheet 1_Autoimmune thyroid disease and human health: a systematic review of Mendelian randomization studies.xlsx by Peijin Li (220400)

“…MR analyses indicated that AITD significantly increased the risk of coronary atherosclerosis, deep venous thrombosis, chronic obstructive pulmonary disease, major depression, diabetic neuropathy, carpal tunnel syndrome, neuromyelitis optica spectrum disorder, diabetic retinopathy, childhood absence epilepsy, rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, inflammatory bowel disease, crohn's disease, vitiligo, myasthenia gravis, alopecia areata, type 1 and type 2 diabetes, sarcoidosis, frozen shoulder, drug eruptions, cataract, early age-related macular degeneration, pernicious anemia, Helicobacter pylori infection, temporomandibular disorders, migraine, frailty, primary biliary cholangitis, knee osteoarthritis, gout, and osteoporosis, while decreasing the risk of lung cancer, polyneuropathies, allergic rhinitis, telomere length, and serum vitamin A levels. …”

Supplementary file 2_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx by Xuan Zhao (356028)

“…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …”

Table 1_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx by Xuan Zhao (356028)

“…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …”

Tilmicosin inhibits the infections of currently prevalent porcine reproductive and respiratory syndrome viruses via the downregulation of CD163 expression by Ming Qiu (762714)

“…In addition, anti-inflammatory factors (such as IL-10) were downregulated, while pro-inflammatory factors (such as IL-1β) were upregulated after tilmicosin treatment. Flow cytometric analysis indicated that anti-inflammatory may reverse the downregulation effect of tilmicosin on CD163, while pro-inflammatory mediators can enhance the downregulation effect of tilmicosin on CD163, which leads to increased and decreased replication of PRRSV, respectively. …”

Data Sheet 1_Chito-oligosaccharide composites enhanced the adaptability of cotton seedlings to salinized soil by modulating photosynthetic efficiency and metabolite.doc by Mengjie An (9501175)

“…The results showed that salt stress reduced the contents of K⁺ and Ca²⁺ and enhanced the content of Na⁺ in cotton leaves compared to the control, which inhibited leaf photosynthesis and seedling growth. COS-PA application decreased leaf Na⁺ content significantly in salt-stressed cotton seedlings by 69.70%, and increased the leaf Ca²⁺ content, fresh weight of each plant part, transpiration rate, leaf chlorophyll concentration (Chl a), actual quantum yield, as well as stomatal conductance by 7.22%, 46.33%-96.36%, 96.65%, 44.53%, 27.15%, and 168.24%, respectively, compared with the no COS-PA application treatment. …”

Table 1_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.xls by Dang Li (16400478)

“…Owing to the poorly understood pathogenesis of keloids and their high recurrence rate, the efficacy of keloid treatment remains unsatisfactory, particularly in patients susceptible to multiple keloids. …”

Table 1_Angiotensin converting enzyme inhibitors and angiotensin receptor blockers impact on the gut microbiome: a systematic review.docx by Elisabeth M. Wang (22480771)

“…In the human study, ACEi/ARB use did not significantly alter microbial diversity, but decreased populations of facultative aerobic pathogens including Staphylococcus and Enterobacterales. …”

Data Sheet 1_Galangin reduces MPTP-induced dopamine neuron injury via the autophagy dependent-PI3K/AKT pathway.pdf by Liping Huang (315281)

“…Moreover, the expression of significantly different genes in the Galangin-treated group and model group analyzed by transcriptomics was basically consistent with the qRT-PCR verification results.…”

Table 1_Ionizing radiation improves skin bacterial dysbiosis in cutaneous T-cell lymphoma.docx by Lauren P. Chrisman (17771613)

“…Both α and β-diversity differed significantly post versus pre-IR for TSEBT, but not for local IR. …”

Table 2_Ionizing radiation improves skin bacterial dysbiosis in cutaneous T-cell lymphoma.xlsx by Lauren P. Chrisman (17771613)

“…Both α and β-diversity differed significantly post versus pre-IR for TSEBT, but not for local IR. …”

Table 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.docx by Yan Cheng (149222)

“…</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …”