Table1_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.DOCX حسب Wen Zhou (49050)

"…The C16 peptide increased the expressions of pTie-2 and Tie-2, integrin αvβ3, and α5β1 and activated the PI3K/Akt signal pathway but decreased the expression of Rho. Co-treatment of C16 with Tie-2 inhibitor and PI3K inhibitor LY294002 attenuated these effects of C16.…"

Negative regulation of reassortant canine influenza virus replication and key site identification in porcine and ferret bronchial epithelial cell lines حسب Jingjing Guo (393650)

"…The viral titer of rKR/07-PB2/NP was significantly lower than those of the parental viruses KR/07 and CA/09. …"

Data Sheet 1_The oncometabolite R-2-hydroxyglutarate inhibits microglial activation via the FTO/NF-κB pathway.docx حسب Lu Wang (45927)

"…The dependency on α-ketoglutarate was tested via metabolite supplementation, and the role of the demethylase FTO was investigated.</p>Results<p>Treatment with glioma CM significantly induced cytokine production in BV2 cells. …"

Image 1_Long-term adoption of plow tillage and green manure improves soil physicochemical properties and optimizes microbial communities under a continuous peanut monoculture syste... حسب Yunfeng Yao (7136525)

"…Peanut pod yields in the PTGM treatment were 14.1 and 7.2% higher compared to the PT and NT treatments, respectively. …"

Supplementary file 1_Cistanche tubulosa glycosides ameliorate cognitive decline in APP/PS1 mice via modulation of gut microbiota and fatty acid metabolism: insights from multi-omic... حسب Rui Hou (161624)

"…The effect of GCT on pure-cultured bacterial strain was assessed via growth curve analysis in vitro.</p>Results<p>GCT treatment significantly improved spatial memory and reduced the protein levels of Aβ and proinflammatory factors in APP/PS1 mice. …"

Data Sheet 1_Identification of key genes and immune infiltration mechanisms in limb ischemia-reperfusion injury: a bioinformatics and experimental study.docx حسب Qiyun Shi (5531150)

"…Pharmacological inhibition confirmed their functional roles: Box5 and U-73122 treatment reduced expression of WNT5A and PLC versus IRI controls (P<0.05), showing IRI-induced muscle fiber disruption, edema, and inflammation. …"

Data Sheet 1_Electroacupuncture ameliorates depression-like behaviors in rats with post-stroke depression by inhibiting ferroptosis in the prefrontal cortex.pdf حسب Jing Gao (69330)

"…Introduction<p>Post-stroke depression (PSD) is the most common complication following a stroke, significantly hindering recovery and rehabilitation in affected patients. …"

Image 1_Inhibition of CRM1 reverses hypoxia-driven chemoresistance in acute myeloid leukemia via overcoming HIF-1α-mediated lysosomal sequestration.jpeg حسب Xiaohui Feng (2869535)

"…Combination treatment with Selinexor and DNR significantly increased apoptosis and DNA damage in vitro and reduced leukemia burden in zebrafish xenografts.…"

Image8_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG حسب Wen Zhou (49050)

"…The C16 peptide increased the expressions of pTie-2 and Tie-2, integrin αvβ3, and α5β1 and activated the PI3K/Akt signal pathway but decreased the expression of Rho. Co-treatment of C16 with Tie-2 inhibitor and PI3K inhibitor LY294002 attenuated these effects of C16.…"

Image10_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG حسب Wen Zhou (49050)

"…The C16 peptide increased the expressions of pTie-2 and Tie-2, integrin αvβ3, and α5β1 and activated the PI3K/Akt signal pathway but decreased the expression of Rho. Co-treatment of C16 with Tie-2 inhibitor and PI3K inhibitor LY294002 attenuated these effects of C16.…"

Data Sheet 1_Metastatic organ count stratifies survival in immunotherapy-treated metastatic colorectal cancer: a retrospective cohort study.docx حسب Hai-Yan Fu (1586935)

"…Therefore, this retrospective study aimed to investigate this issue to derive a clear conclusion to facilitate clinical treatment.</p>Methods<p>This retrospective cohort study included 208 patients with mCRC receiving immunotherapy at the Sun Yat-sen University Cancer Center. …"

Presentation 1_Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammat... حسب Jingjian Dong (12458730)

"…</p>Results<p>PSPA significantly reduced joint swelling and structural damage in CIA rats, with the highest dose (40 mg/kg) reducing tissue hyperplasia and inflammatory infiltration. …"

Data Sheet 1_Prognostic value of lymph node ratio in patients with non-small cell lung cancer: a systematic review and meta-analysis.zip حسب Junhuang Zheng (21629486)

"…</p>Results<p>This meta-analysis included 11 studies. High LNR was significantly associated with decreased overall survival (OS) (multivariable HR=1.76, 95% CI=1.36-2.27; univariable HR=2.26, 95% CI=1.95-2.63) and increased risk of shorter disease-free survival (DFS) (multivariable HR=1.66, 95% CI=1.48-1.88). …"

Image5_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.jpeg حسب Wen Zhou (49050)

"…The C16 peptide increased the expressions of pTie-2 and Tie-2, integrin αvβ3, and α5β1 and activated the PI3K/Akt signal pathway but decreased the expression of Rho. Co-treatment of C16 with Tie-2 inhibitor and PI3K inhibitor LY294002 attenuated these effects of C16.…"

DataSheet1_Enhancing resistant starch fraction in modified elephant foot yam starch: optimizing preparation conditions and exploring tribological properties.pdf حسب Sreejani Barua (13810723)

"…However, this retention decreased significantly to 1.08% after 10 min of cooking. …"

Novel Vanillic Acid-Loaded <i>In Situ</i> Gels: Development, Characterization, <i>In Vitro</i> Evaluation for Enhanced Wound Healing and Skin Irritation Test حسب Gökçe Mutlu Sonat (21726037)

"…The results suggest that these vanillic acid-loaded <i>in situ</i> gels hold promising potential in wound treatment due to their sustained release over 48 hours.…"

<b>Metabolic Improvements with Tirzepatide in Lipodystrophy: A Novel Option?</b> حسب Rasimcan Meral (5022425)

"…Conclusions: Tirzepatide may be an effective treatment for patients with lipodystrophy.</p>…"

Image 1_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff حسب José De Jesus Bravo-Silva (21898316)

"…</p>Results<p>Melatonin treatment significantly reduced ZIKV and DENV-4 replication and the associated inflammatory response in U87-MG cells. …"

Table 1_Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammatory cel... حسب Jingjian Dong (12458730)

"…</p>Results<p>PSPA significantly reduced joint swelling and structural damage in CIA rats, with the highest dose (40 mg/kg) reducing tissue hyperplasia and inflammatory infiltration. …"

Image4_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG حسب Wen Zhou (49050)

"…The C16 peptide increased the expressions of pTie-2 and Tie-2, integrin αvβ3, and α5β1 and activated the PI3K/Akt signal pathway but decreased the expression of Rho. Co-treatment of C16 with Tie-2 inhibitor and PI3K inhibitor LY294002 attenuated these effects of C16.…"