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significant treatment » significant investment (Expand Search), significant enrichment (Expand Search), significant impairment (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
treatment decrease » treatment decreased (Expand Search), treatments decreased (Expand Search), treatment increases (Expand Search)
significant treatment » significant investment (Expand Search), significant enrichment (Expand Search), significant impairment (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
treatment decrease » treatment decreased (Expand Search), treatments decreased (Expand Search), treatment increases (Expand Search)
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5141
Supplementary file 1_Single-cell transcriptomics identifies FOSL1-regulated IGFBP3+ melanoma subtype as a neuro-immunoregulatory signaling hub facilitating tumor progression.docx
Published 2025“…The C2 subtype was strongly linked with FOSL1 expression, which may affect gene transcription and illness progression. FOSL1 knockdown significantly increased apoptosis and decreased melanoma cell motility and proliferation in vitro.…”
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5142
Flowchart of Study Design and Analysis.
Published 2025“…</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …”
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5143
Table_1_Angiotensin-I-converting enzyme inhibitory peptides from eel (Anguilla japonica) bone collagen: preparation, identification, molecular docking, and protective function on H...
Published 2024“…Lineweaver-Burk plots revealed that GPPGPPGL competitively bound to ACE’s active site residues. Treatment with GPPGPPGL significantly increased nitric oxide secretion (p < 0.01) and decreased endothelin-1 (ET-1) production in HUVECs.…”
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5144
Data Sheet 1_Modified ZhuJing pill protects retinal pigment epithelium against oxidative stress-induced epithelial–mesenchymal transition through Nrf2-mediated Akt/GSK3β pathway.do...
Published 2025“…Notably, the EMT-suppressing effect of mZJP was significantly attenuated upon Nrf2 silencing, as evidenced by enhanced cell migration, decreased epithelial marker expression (E-cadherin), increased mesenchymal marker expression (vimentin and α-SMA), suppression of the Nrf2 pathway, and activation of the Akt/GSK3β pathway.…”
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5145
Image 4_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tiff
Published 2025“…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …”
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5146
Multivariate Binary Logistic Regression Analysis.
Published 2025“…</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …”
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5147
Image 1_Metformin attenuates alveolar bone destruction in mice with apical periodontitis and inhibits pro-inflammatory cytokine synthesis in lipopolysaccharide-stimulated RAW264.7...
Published 2025“…</p>Results<p>Metformin significantly reduced periapical bone destruction on postoperative days 21 and 28, and decreased the number of osteoclasts on the periapical alveolar bone on postoperative day 28. …”
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5148
Data Sheet 1_Tcirg1 deficiency delays osteoarthritis progression by impairing lysosome acidification and peripheral accumulation in osteoclasts.docx
Published 2025“…This study aims to assess the impact of Tcirg1 on OA progression and to explore its therapeutic potential for the disease treatment.</p>Methods<p>Proteomic comparison of weight-bearing region (WBR) versus non-weight-bearing region (NWBR) of the subchondral bone was performed in 20 OA patients undergoing total knee arthroplasty. …”
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5149
Image_3_Angiotensin-I-converting enzyme inhibitory peptides from eel (Anguilla japonica) bone collagen: preparation, identification, molecular docking, and protective function on H...
Published 2024“…Lineweaver-Burk plots revealed that GPPGPPGL competitively bound to ACE’s active site residues. Treatment with GPPGPPGL significantly increased nitric oxide secretion (p < 0.01) and decreased endothelin-1 (ET-1) production in HUVECs.…”
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5150
Image 2_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno...
Published 2025“…Background<p>Minimally invasive esophagectomy (MIE) is commonly applied in the treatment of esophageal squamous cell carcinoma (ESCC). …”
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5151
Image 3_Metformin attenuates alveolar bone destruction in mice with apical periodontitis and inhibits pro-inflammatory cytokine synthesis in lipopolysaccharide-stimulated RAW264.7...
Published 2025“…</p>Results<p>Metformin significantly reduced periapical bone destruction on postoperative days 21 and 28, and decreased the number of osteoclasts on the periapical alveolar bone on postoperative day 28. …”
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5152
ROC curve.
Published 2025“…</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …”
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5153
Image 4_Metformin attenuates alveolar bone destruction in mice with apical periodontitis and inhibits pro-inflammatory cytokine synthesis in lipopolysaccharide-stimulated RAW264.7...
Published 2025“…</p>Results<p>Metformin significantly reduced periapical bone destruction on postoperative days 21 and 28, and decreased the number of osteoclasts on the periapical alveolar bone on postoperative day 28. …”
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5154
Table 1_Global, regional, and national burden of myocarditis and its attributable risk factors in 204 countries and territories from 1990 to 2021: updated systematic analysis.docx
Published 2025“…Concurrently, the age-standardized prevalence rate (ASPR) per 100,000 people also saw a slight increase (no statistical significance) from 6.35 (5.37 to 7.36) to 6.41 (5.48 to 7.44). …”
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5155
Image 2_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tiff
Published 2025“…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …”
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5156
Image 1_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno...
Published 2025“…Background<p>Minimally invasive esophagectomy (MIE) is commonly applied in the treatment of esophageal squamous cell carcinoma (ESCC). …”
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5157
Data Sheet 1_Individual alpha frequency tACS reduces static functional connectivity across the default mode network.docx
Published 2025“…</p>Results<p>IAF-tACS significantly decreased sFC in intra- and inter-DMN links in the stimulation group compared to the sham group, with a special influence over antero-posterior links between hubs of the DMN. …”
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5158
Unmatched data.
Published 2025“…</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …”
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5159
Table 1_Polygonatum cyrtonema Hua polysaccharides alleviate muscle atrophy and fat lipolysis by regulating the gut microenvironment in chemotherapy-induced cachexia.docx
Published 2025“…</p><p>Results: This study demonstrated that PCPs significantly mitigated body weight loss, restored muscle fiber atrophy and mitochondrial disorder, alleviated adipose tissue wasting, strengthened the intestinal barrier integrity, and decreased the intestinal inflammation in chemotherapy-induced cachexia. …”
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5160
Image 2_Metformin attenuates alveolar bone destruction in mice with apical periodontitis and inhibits pro-inflammatory cytokine synthesis in lipopolysaccharide-stimulated RAW264.7...
Published 2025“…</p>Results<p>Metformin significantly reduced periapical bone destruction on postoperative days 21 and 28, and decreased the number of osteoclasts on the periapical alveolar bone on postoperative day 28. …”