Illustrative examples of our study. حسب Mustafa Tuşat (21094179)

Four grid table. حسب Xiaoling Zhong (181270)

"…The median time to onset of all AEs was 61 days, with the majority occurring within the first month of treatment. Notably, a significant number of AEs persisted beyond one year of treatment.…"

Four major algorithms used for signal detection. حسب Xiaoling Zhong (181270)

"…The median time to onset of all AEs was 61 days, with the majority occurring within the first month of treatment. Notably, a significant number of AEs persisted beyond one year of treatment.…"

All data used in the article. حسب Mustafa Tuşat (21094179)

"…It was determined that EO treatment significantly reduced the histopathological damage and the caspase-3 (CASP3) expression level in the lung (p < 0.001).…"

Lung injury scoring system. حسب Mustafa Tuşat (21094179)

"…It was determined that EO treatment significantly reduced the histopathological damage and the caspase-3 (CASP3) expression level in the lung (p < 0.001).…"

Content of EO administered to rats. حسب Mustafa Tuşat (21094179)

"…It was determined that EO treatment significantly reduced the histopathological damage and the caspase-3 (CASP3) expression level in the lung (p < 0.001).…"

Prediction of the effect of the 9 nsSNPs on AKT2 proteins’ structure and function by eight computational tools. حسب Sadia Afrin Runa (22504971)

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Distribution of SNPs and their frequencies based on mutation classes. حسب Sadia Afrin Runa (22504971)

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Hydrogen bond interactions between Capivasertib (red) and the AKT2 protein (blue) as predicted by molecular docking analyses. حسب Sadia Afrin Runa (22504971)

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Hydrogen bond interactions between Ipatasertib (red) and the AKT2 protein (blue) as predicted by molecular docking analyses. حسب Sadia Afrin Runa (22504971)

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Hydrogen bond interactions between Akt1/Akt2-IN-1 (red) and the AKT2 protein (blue) as predicted by molecular docking analyses. حسب Sadia Afrin Runa (22504971)

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Predicted pathogenicity of R274H, Y265N, and R467W substitutions and their molecular mechanisms. حسب Sadia Afrin Runa (22504971)

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The Fig illustrates the effects of mutations on the stability, flexibility, compactness, and interactions of the AKT2-Akt1/Akt2-IN-1 through molecular dynamics simulations. حسب Sadia Afrin Runa (22504971)

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Non-covalent interactions between Capivasertib (ball stick) and the AKT2 protein as predicted by molecular docking analyses. حسب Sadia Afrin Runa (22504971)

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Non-covalent interactions between Akt1/Akt2-IN-1 (ball stick) and the AKT2 protein as predicted by molecular docking analyses. حسب Sadia Afrin Runa (22504971)

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Binding affinity of Akt1/Akt2-IN-1, Capivasertib, and Ipatasertib with AKT2 (wild and mutants) protein. حسب Sadia Afrin Runa (22504971)

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Superimposed structures of AKT2 native (green color) and mutant (red color) models to visualize the stereochemical conformation of wild type and mutant residues at (a) 274, (b) 265... حسب Sadia Afrin Runa (22504971)

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The Fig illustrates the effects of mutations on the stability, flexibility, compactness, and interactions of the AKT2-Ipatasertib complex through molecular dynamics simulations. حسب Sadia Afrin Runa (22504971)

الموضوعات:

Non-covalent interactions between Ipatasertib (ball stick) and the AKT2 protein as predicted by molecular docking analyses. حسب Sadia Afrin Runa (22504971)

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The Fig appears to depict the results of conservation profile of amino acids of protein AKT2. حسب Sadia Afrin Runa (22504971)

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