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significant variations » significant associations (Expand Search), significant implications (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
variations decrease » variation increases (Expand Search)
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1021
Image 1_Global, regional, and national epidemiology of congenital heart disease in children from 1990 to 2021.tif
Published 2025“…Background<p>Congenital heart disease (CHD) is a leading cause of morbidity and mortality in children globally, with significant variations in outcomes across different regions.…”
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1022
Data Sheet 1_Global burden of Type 2 Diabetes Mellitus attributable to dietary risks in elderly adults: insights from the Global Burden of Disease study 2021.docx
Published 2025“…This study aims to comprehensively quantify the global burden of T2DM attributable to dietary risks among elderly adults, identify significant dietary risk factors driving disease burden, and evaluate temporal, regional, and demographic variations to inform targeted public health strategies and interventions for reducing the impact of T2DM.…”
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1023
Data Sheet 1_Exploratory study on the ascending pain pathway in patients with chronic neck and shoulder pain based on combined brain and spinal cord diffusion tensor imaging.docx
Published 2025“…FA values of the left STT (C2 segment, C5 segment) and right STT (C1 segment, C2 segment) were significantly decreased in bilateral cervical STTs of CNSP patients; MD values of the left STT (C1 segment, C2 segment, C5 segment) and right STT (C1 segment, C5 segment) were significantly increased (p < 0.05). …”
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1024
Supplementary file 1_Analysis of gut and circulating microbiota characteristics in patients with liver cirrhosis and portal vein thrombosis.docx
Published 2025“…</p>Results<p>(1) Gut microbiota showed no α-diversity difference between groups, but β-diversity differed significantly. PVT patients had increased Gram-negative bacteria (such as Escherichia-Shigella) and decreased SCFA-producing taxa. (2) Compared with peripheral vein microbiota, portal vein microbiota showed significant difference in α diversity and β diversity in cirrhotic patients with PVT, with Massilia enriched. (3) Portal microbiota had the highest diagnostic value for PVT (AUC = 0.95). (4) The tPVT group had more portal-feces shared genera than the tNPVT group (49 vs. 29). …”
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1025
Data Sheet 1_Global, regional, and national burden of fracture of vertebral column, 1990–2021: analysis of data from the global burden of disease study 2021.docx
Published 2025“…</p>Conclusion<p>Our findings highlight the substantial and growing global burden of vertebral column fractures, with significant variations across regions and countries. …”
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1026
Image 2_The global burden of lead exposure-related ischemic stroke: based on Bayesian age-period-cohort analysis.png
Published 2025“…Clustering analysis revealed region-specific variations. The BAPC model predicts differing global trends in lead exposure-related ischemic stroke burden genders, with females expecting stable cases but decreasing rates, while males anticipate declines in all indicators over the next 11 years.…”
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1027
Table 1_The global burden of lead exposure-related ischemic stroke: based on Bayesian age-period-cohort analysis.docx
Published 2025“…Clustering analysis revealed region-specific variations. The BAPC model predicts differing global trends in lead exposure-related ischemic stroke burden genders, with females expecting stable cases but decreasing rates, while males anticipate declines in all indicators over the next 11 years.…”
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1028
Image 3_The global burden of lead exposure-related ischemic stroke: based on Bayesian age-period-cohort analysis.png
Published 2025“…Clustering analysis revealed region-specific variations. The BAPC model predicts differing global trends in lead exposure-related ischemic stroke burden genders, with females expecting stable cases but decreasing rates, while males anticipate declines in all indicators over the next 11 years.…”
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1029
Image 1_The global burden of lead exposure-related ischemic stroke: based on Bayesian age-period-cohort analysis.png
Published 2025“…Clustering analysis revealed region-specific variations. The BAPC model predicts differing global trends in lead exposure-related ischemic stroke burden genders, with females expecting stable cases but decreasing rates, while males anticipate declines in all indicators over the next 11 years.…”
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1030
Table 1_Effects of gut microbiota dysbiosis on the metabolism and pharmacokinetics of losartan in rats: from endogenous to ceftriaxone-induced dysbiosis.docx
Published 2025“…</p>Results<p>The results showed that the intestinal flora from SHRs led to a more significant degradation of losartan than that from Wistar Kyoto rats (WKYs) in vitro. …”
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1031
Data Sheet 1_Primary care and specialist physicians’ prescribing preferences for concurrent probiotic-antibiotic therapy: a multinational clinical practice survey across 13 countri...
Published 2025“…<p>Antibiotic-induced intestinal microbiota disruption represents a significant clinical concern, yet physician practices regarding concurrent probiotic supplementation remain poorly characterized across international healthcare systems. …”
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1032
DataSheet_1_FCGR2/3 polymorphisms are associated with susceptibility to Kawasaki disease but do not predict intravenous immunoglobulin resistance and coronary artery aneurysms.docx
Published 2024“…Treatment with intravenous immunoglobulin (IVIg) significantly decreases the risk of CAA, possibly through competitive binding to Fc-gamma receptors (FcγRs), which reduces the binding of pathological immune complexes. …”
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1033
Data Sheet 1_The impact of sublethal antimicrobial blue light on lipidomic changes of Escherichia coli and Salmonella Typhimurium.pdf
Published 2025“…We identified more than 70 lipid species across 6 classes, with over 50% showing significant variations in profile, intensity, and degree of unsaturation following aBL exposure. …”
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1034
Data Sheet 3_The impact of sublethal antimicrobial blue light on lipidomic changes of Escherichia coli and Salmonella Typhimurium.csv
Published 2025“…We identified more than 70 lipid species across 6 classes, with over 50% showing significant variations in profile, intensity, and degree of unsaturation following aBL exposure. …”
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1035
Data Sheet 2_The impact of sublethal antimicrobial blue light on lipidomic changes of Escherichia coli and Salmonella Typhimurium.csv
Published 2025“…We identified more than 70 lipid species across 6 classes, with over 50% showing significant variations in profile, intensity, and degree of unsaturation following aBL exposure. …”
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1036
Enhancement of mechanical and thermal properties of porous alkaline cements using silica and alumina nanoparticles
Published 2025“…Al nanoparticles did not enhance mechanical performance, but led to density reduction, resulting in decreased strength. Thermal conductivity showed no significant variations due to nanoparticles, with all formulations classified as T2 thermal mortars. …”
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1037
Supplementary file 1_Burden of urogenital congenital anomalies: findings from the global burden of disease study 2021.docx
Published 2025“…Regionally, Southern Sub-Saharan Africa exhibited the highest prevalence, while Oceania and East Asia showed significant increases and decreases, respectively. Decomposition analysis of change in prevalence indicated that, globally, population contributed the most to changes in prevalence, followed by aging and epidemiological change. …”
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1038
Supplementary file 2_Burden of urogenital congenital anomalies: findings from the global burden of disease study 2021.pdf
Published 2025“…Regionally, Southern Sub-Saharan Africa exhibited the highest prevalence, while Oceania and East Asia showed significant increases and decreases, respectively. Decomposition analysis of change in prevalence indicated that, globally, population contributed the most to changes in prevalence, followed by aging and epidemiological change. …”
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1039
Table 1_The impact of climate change on medicinal plants and natural products: A scoping review.pdf
Published 2025“…Data were extracted to summarize study characteristics, climate change factors, species distribution, bioactive metabolites and marker compounds variations, and healthcare implications.</p>Results<p>A total of 219 studies were included, showing a significant increase in publication after 2021. …”
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1040
Table 3_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.xlsx
Published 2024“…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”