Data Sheet 1_Nutraceutical supplement slim reshaped colon histomorphology and reduces Mucispirillum schaedleri in obese mice.docx by Jessica Alves Freitas (20974076)

“…</p>Results<p>Our results demonstrated that Slim supplementation significantly improved lipid metabolism, reshaped colon histomorphology, and decreased levels of Mucispirillum schaedleri, which were correlated with VLDL-c and triglycerides.…”

H2AK119ub is depleted from facultative heterochromatin as the cerebellum matures. by Aditya Parmar (22331873)

“…<b>(D)</b> Volcano plot depicting H2AK119ub abundance, as detected in normalized CUT&RUN data from early and late cerebellum, within H3K27me peak regions identified by SEACR in the early cerebellum. The significance threshold was a p-value <0.05, as computed using edgeR [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011843#pgen.1011843.ref071" target="_blank">71</a>] and limma [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011843#pgen.1011843.ref072" target="_blank">72</a>] (n = 4). …”

Data Sheet 1_HAX1, gene responsible for Kostmann syndrome, regulates gingival epithelial barrier function via intracellular trafficking of JAM1.pdf by Keita Tanigaki (13162449)

“…In HAX1-knockdown IHGE cells, significantly decreased levels of JAM1 were found. Additionally, cisplatin, a chemotherapeutic agent reported to inhibit HAX1, also led to decreased expression of both HAX1 and JAM1. …”

Deletion of glycosyltransferase <i>galE</i> impairs the InlB anchoring and pathogenicity of <i>Listeria monocytogenes</i> by Xiaowei Fang (696967)

“…In this study, we deleted the <i>galE</i> gene, which is involved in galactosylation, from <i>L. monocytogenes</i> strain ScottA. We found that <i>galE</i> deletion reduced InlB anchoring, weakened bacterial adhesion and invasion of Caco-2 cells (human colorectal adenocarcinoma cells) and MGC803 cells (human gastric carcinoma cells), increased phagocytosis but decreased proliferation in RAW264.7 cells (mouse mononuclear macrophage leukaemia cells), and decreased bacteria load, mortality, and tissue damage in infected mice. …”

Data Sheet 1_Investigation of the physiological and molecular regulatory mechanism of soluble sugar metabolism in Lavandula angustifolia Mill. under cold stress.docx by Yuchen Liang (8596404)

“…<p>Lavender (Lavandula angustifolia Mill.) is a valuable aromatic plant with significant commercial importance. …”

<b>Canagliflozin-induced adaptive metabolism in bone</b> by Sher Bahadur Poudel (20686192)

“…Beyond this, these drugs induce various metabolic changes, including weight loss and impaired bone integrity. There is a significant gap in understanding SGLT2i-induced skeletal changes, as SGLT2 is not expressed in osteoblasts or osteocytes, which use glucose to remodel the bone matrix. …”

Database of the impact of temperature on development of Aedes aegypti and Aedes albopictus in Cambodia by Bros Doeurk (21163097)

“…The experiment was conducted in a climatic chamber with temperatures ranging from 15°C to 40°C, with a 5°C incrementation between each treatment. …”

S1 Raw data - by Dao-Cheng Zhou (20314697)

“…All-cause and CVD mortality gradually decreased with increasing ideal LE8 metrics. LE8 was not significantly associated with cancer mortality. …”

PVD neurons show reduced lysosome function during aging and in the <i>hlh-30</i> mutant. by Ruiling Zhong (22339779)

“…<p><b>(A–D)</b> A fluorescent reporter for luminal acidity of neuronal lysosomal compartments shows that acidity decreases with aging and in the <i><i>hlh-30</i></i> mutant. …”

Data for “Impact of multiscale heterogeneous sediments and boundary conditions on dispersivity spatial variations” by Ziqi Ma (12099365)

“…These experiments contain various sedimentary structures, including several nearly-homogeneous column tests, a heterogeneous column test, a horizontally stratified tank experiment, a randomly filled tank experiment, and a three-dimensional tank experiment utilizing an analogous simulation to a field-scale site. …”

Data Sheet 1_Cognitive component of auditory attention to natural speech events.pdf by Nhan Duc Thanh Nguyen (20506628)

“…Importantly, the component decreases in strength but is still significantly observable in increasingly realistic paradigms of multi-talker environments. …”

Supplementary file 1_Rotation of soybean and Corydalis yanhusuo enhances yield and active compounds of C. yanhusuo via soil nutrient optimisation and rhizosphere microbiome enginee... by Jia Liu (41593)

“…Microbial OTUs increased in the bulk soil, rhizosphere soil, and roots, along with significant improvements in α-diversity. Over time, the Proteobacteria and pathogenic genera decreased, while Firmicutes and other beneficial genera increased. …”

Supplementary file 1_Lurasidone induces developmental toxicity and behavioral impairments in zebrafish embryos.docx by Wentian Li (28857)

“…Neurotransmitter profiling showed significant reductions in glutamate, dopamine, and GABA levels.…”

Image 1_Can Chinese patients restore normal knee function 1 year after total knee arthroplasty?.jpeg by YiShun Guo (22629887)

“…Based on expert and patient focus group discussions, a set of evaluation items was established, followed by designing a self-administered questionnaire assessing importance, frequency, and difficulty. …”

Image 3_Can Chinese patients restore normal knee function 1 year after total knee arthroplasty?.jpeg by YiShun Guo (22629887)

“…Based on expert and patient focus group discussions, a set of evaluation items was established, followed by designing a self-administered questionnaire assessing importance, frequency, and difficulty. …”

Image 2_Can Chinese patients restore normal knee function 1 year after total knee arthroplasty?.jpeg by YiShun Guo (22629887)

“…Based on expert and patient focus group discussions, a set of evaluation items was established, followed by designing a self-administered questionnaire assessing importance, frequency, and difficulty. …”

Control analyses of behavioral timescales. by Isabel Raposo (21615517)

“…<p><b>(A)</b> Left: Randomly shuffling the time series data abolishes the signal autocorrelation; hence, removes the aperiodic temporal structure as indexed by decreasing timescales (<i>p</i> < 0.0001; <i>z</i>-scored relative to shuffled distribution). …”

Table 1_Aerobic exercise ameliorates atherosclerosis-induced cognitive impairment via hippocampal IL-33/NF-κB signaling modulation.xlsx by Jianwei Peng (811819)

“…Then, AS mice were divided into sedentary (AS-SED) and exercise (AS-EX) groups for a 10-week aerobic exercise intervention. Results showed significant aortic plaques and cognitive deficits in AS mice after 6 weeks on the HFHCD diet. …”

Data Sheet 1_Aerobic exercise ameliorates atherosclerosis-induced cognitive impairment via hippocampal IL-33/NF-κB signaling modulation.xlsx by Jianwei Peng (811819)

“…Then, AS mice were divided into sedentary (AS-SED) and exercise (AS-EX) groups for a 10-week aerobic exercise intervention. Results showed significant aortic plaques and cognitive deficits in AS mice after 6 weeks on the HFHCD diet. …”

Effect of soil salinity on cotton cultivation and the potential for introducing <i>Amaranthaceae</i> halophytes in the Yellow River Delta, China by Hiroshi Takagi (271173)

“…Levels of major (K⁺, Ca²⁺ and Mg²⁺) or minor (Fe²⁺, Mn²⁺, Zn²⁺ and Cu²⁺) essential elements were not significantly decreased by the increase of field EC in any plant species, except for K⁺ in <i>S</i>. …”