Data Sheet 1_Disproportionate impact of the COVID-19 pandemic on socially vulnerable communities: the case of Jane and Finch in Toronto, Ontario.docx حسب Zahra Movahedi Nia (9238798)

"…</p>Results<p>The Jane and Finch community had a significantly (p < 0.0001) higher number of COVID-19 cases, hospitalizations, and mortalities. …"

Data Sheet 2_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.pdf حسب Linjie Peng (12553717)

"…Pathological analysis demonstrated that TB001 treatment reduced inflammatory cell infiltration and downregulated the expression of fibrosis markers, including TGF-β1, α-SMA, COL1A1, and Vimentin. Further transcriptome sequencing of kidney grafts revealed that TB001-treated group had a gene expression pattern similar to that of the syngeneic control group and showed significant enhancement of lipid metabolism-related pathways, particularly the PPAR pathway. …"

Data_Sheet_1_Cytomegalovirus results in poor graft function via bone marrow-derived endothelial progenitor cells.pdf حسب Weiran Lv (715679)

"…Introduction<p>Poor graft function (PGF), characterized by myelosuppression, represents a significant challenge following allogeneic hematopoietic stem cell transplantation (allo-HSCT) with human cytomegalovirus (HCMV) being established as a risk factor for PGF. …"

Data Sheet 3_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.zip حسب Linjie Peng (12553717)

"…Pathological analysis demonstrated that TB001 treatment reduced inflammatory cell infiltration and downregulated the expression of fibrosis markers, including TGF-β1, α-SMA, COL1A1, and Vimentin. Further transcriptome sequencing of kidney grafts revealed that TB001-treated group had a gene expression pattern similar to that of the syngeneic control group and showed significant enhancement of lipid metabolism-related pathways, particularly the PPAR pathway. …"

Clinical and Imaging Characteristics of Posterior Scleritis in Children حسب Ayala Katzir (20605679)

"…Retinal nerve fiber layer (RNFL) was thickened in all examined eyes (mean±SD 136.2 ± 28.4 µm) at presentation and it significantly decreased with treatment (109.8 ± 8.2 µm two months later). …"

DataSheet1_Population pharmacokinetic study of the effect of polymorphisms in the ABCB1 and CES1 genes on the pharmacokinetics of dabigatran.docx حسب Zhuan Yang (18251657)

"…</p>Results<p>The results showed that covariates food intake and ABCB1 SNP rs4148738 were shown to have statistically significant impacts. Specifically, in postprandial administration increased lag time (ALAG) and clearance (CL) by 2.65% and 0.51%, respectively, and decreased absorption rate constant (KA) by 0.24%. …"

Image 4_Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.tif حسب Jorgo Lika (21189020)

"…Treatment with these inhibitors also impacts neutrophil redox status, migration, and apoptosis without significantly changing overall bioenergetics.</p>Conclusions<p>Together, these results demonstrate that mitochondrial metabolism is dynamically remodeled and plays a significant role in neutrophils. …"

Data Sheet 4_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.pdf حسب Linjie Peng (12553717)

"…Pathological analysis demonstrated that TB001 treatment reduced inflammatory cell infiltration and downregulated the expression of fibrosis markers, including TGF-β1, α-SMA, COL1A1, and Vimentin. Further transcriptome sequencing of kidney grafts revealed that TB001-treated group had a gene expression pattern similar to that of the syngeneic control group and showed significant enhancement of lipid metabolism-related pathways, particularly the PPAR pathway. …"

Table 2_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.docx حسب Linjie Peng (12553717)

"…Pathological analysis demonstrated that TB001 treatment reduced inflammatory cell infiltration and downregulated the expression of fibrosis markers, including TGF-β1, α-SMA, COL1A1, and Vimentin. Further transcriptome sequencing of kidney grafts revealed that TB001-treated group had a gene expression pattern similar to that of the syngeneic control group and showed significant enhancement of lipid metabolism-related pathways, particularly the PPAR pathway. …"

Data_Sheet_2_Cytomegalovirus results in poor graft function via bone marrow-derived endothelial progenitor cells.pdf حسب Weiran Lv (715679)

"…Introduction<p>Poor graft function (PGF), characterized by myelosuppression, represents a significant challenge following allogeneic hematopoietic stem cell transplantation (allo-HSCT) with human cytomegalovirus (HCMV) being established as a risk factor for PGF. …"

Image 1_Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.tif حسب Jorgo Lika (21189020)

"…Treatment with these inhibitors also impacts neutrophil redox status, migration, and apoptosis without significantly changing overall bioenergetics.</p>Conclusions<p>Together, these results demonstrate that mitochondrial metabolism is dynamically remodeled and plays a significant role in neutrophils. …"

Image_1_Cytomegalovirus results in poor graft function via bone marrow-derived endothelial progenitor cells.PNG حسب Weiran Lv (715679)

"…Introduction<p>Poor graft function (PGF), characterized by myelosuppression, represents a significant challenge following allogeneic hematopoietic stem cell transplantation (allo-HSCT) with human cytomegalovirus (HCMV) being established as a risk factor for PGF. …"

Supplementary Materials -Table حسب Shaojie Zhang (20807333)

"…<p dir="ltr">Exposure to hypobaric hypoxia during rapid ascent to high altitudes significantly impacts intestinal barrier function. Goblet cells, as one of the primary cell types in the intestinal mucosa, play a crucial role in maintaining this barrier. …"

Image 2_Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.tif حسب Jorgo Lika (21189020)

"…Treatment with these inhibitors also impacts neutrophil redox status, migration, and apoptosis without significantly changing overall bioenergetics.</p>Conclusions<p>Together, these results demonstrate that mitochondrial metabolism is dynamically remodeled and plays a significant role in neutrophils. …"

Table 1_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.docx حسب Linjie Peng (12553717)

"…Pathological analysis demonstrated that TB001 treatment reduced inflammatory cell infiltration and downregulated the expression of fibrosis markers, including TGF-β1, α-SMA, COL1A1, and Vimentin. Further transcriptome sequencing of kidney grafts revealed that TB001-treated group had a gene expression pattern similar to that of the syngeneic control group and showed significant enhancement of lipid metabolism-related pathways, particularly the PPAR pathway. …"

Table 1_Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19.docx حسب Giuseppe G. F. Leite (18186056)

"…<p>The COVID-19 pandemic has significantly impacted global health, especially in vulnerable populations like kidney transplant recipients (KTRs). …"

Table 3_Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19.xlsx حسب Giuseppe G. F. Leite (18186056)

"…<p>The COVID-19 pandemic has significantly impacted global health, especially in vulnerable populations like kidney transplant recipients (KTRs). …"

Image_2_Cytomegalovirus results in poor graft function via bone marrow-derived endothelial progenitor cells.PNG حسب Weiran Lv (715679)

"…Introduction<p>Poor graft function (PGF), characterized by myelosuppression, represents a significant challenge following allogeneic hematopoietic stem cell transplantation (allo-HSCT) with human cytomegalovirus (HCMV) being established as a risk factor for PGF. …"

Data Sheet 1_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.pdf حسب Linjie Peng (12553717)

"…Pathological analysis demonstrated that TB001 treatment reduced inflammatory cell infiltration and downregulated the expression of fibrosis markers, including TGF-β1, α-SMA, COL1A1, and Vimentin. Further transcriptome sequencing of kidney grafts revealed that TB001-treated group had a gene expression pattern similar to that of the syngeneic control group and showed significant enhancement of lipid metabolism-related pathways, particularly the PPAR pathway. …"

DataSheet1_Engineered myeloid precursors differentiate into osteoclasts and resorb heterotopic ossification in mice.docx حسب Cameron Rementer (20310858)

"…Once symptomatic, HO causes pain, limited mobility and decreased quality of life. Current treatments are limited and have significant complications with high recurrence rates, underscoring the need for improved therapeutic interventions. …"