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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
altered decrease » altered release (Expand Search), observed decrease (Expand Search), teer decrease (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
altered decrease » altered release (Expand Search), observed decrease (Expand Search), teer decrease (Expand Search)
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21041
Supplementary file 1_Oral bacterial community dynamics during induction of gingival inflammation.docx
Published 2025“…</p>Results<p>The study revealed pronounced microbial changes, particularly in supragingival plaque, where Leptotrichia and Prevotella increased while Streptococcus decreased. Alpha diversity significantly increased in supragingival plaque, tongue, and saliva during gingivitis induction, highlighting shifts in microbial complexity. …”
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21042
Table 1_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.docx
Published 2025“…</p>Results<p>We found that, in addition to ACTR3C, 17 ARPs were significantly overexpressed in HCC compared with normal tissues. …”
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21043
<i>Salmonella </i>Typhimurium <i>StiP</i>-mediated upregulation of membrane protein Alx drives complement evasion via CFI-dependent C3b degradation
Published 2025“…Invasive strains exhibited significantly enhanced serum resistance (>17-fold survival in 75% isolates) and HeLa cell invasive ability (minimum bacterial loads 3.93 × 10⁵ CFU/mL) compared to non-invasive strains (< 9.8-fold survival; maximum bacterial loads 1.47 × 10⁵ CFU/mL). …”
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21044
Presentation 1_Anti-PD1 therapies induce an early expansion of Ki67+CD8+ T cells in metastatic non-oncogene addicted NSCLC patients.pptx
Published 2024“…Concurrently, 14 soluble immune checkpoints were analyzed by Luminex assay. Immunotherapy significantly increased the levels of Ki67<sup>+</sup>(total and CD8<sup>+</sup>) T cells, PMN(Lox1<sup>+</sup>)-MDSCs, non-suppressive Tregs (nsTregs), and soluble PD1 from T0 to T1 in the entire NSCLC population, while decreased active Tregs. …”
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21045
Image 5_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno...
Published 2025“…Accordingly, we developed the SNS staging and found that the OS and DFS were significantly different among patients at different stages (all P < 0.001). …”
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21046
Table 1_Moderating effects of a healthy lifestyle on the association of pre-metabolic syndrome with multiple chronic disease comorbidities.docx
Published 2025“…PreMetS [OR = 1.38, 95%CI: 1.16–1.64] and MetS [OR = 1.61, 95%CI: 1.32–1.97] were associated with a significantly higher risk of multiple comorbidities compared with the normal population, and the risk of multiple comorbidities tended to increase as the number of metabolic disorder components increased (p < 0.001). …”
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21047
Glucagon-like peptide-1 receptor agonists, inflammation, and kidney diseases: evidence from Mendelian randomization
Published 2025“…</p> <p>After meta-analyses of both discovery and validation cohorts, genetically proxied GLP1R agonist was found to significantly associated with a decreased risk of diabetic nephropathy (OR = 0.72, 95%CI = 0.54–0.97, <i>p</i> = 0.031) and IgA nephropathy (OR = 0.58, 95%CI = 0.36–0.94, <i>p</i> = 0.027). …”
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21048
Data Sheet 1_Dietary resveratrol and β-Hydroxy-β-Methylbutyric acid enhance flavor and modulate intramuscular fat in Tibetan sheep: insights from transcriptomics and lipidomics.zip...
Published 2025“…Among medium- and long-chain fatty acids, the H-RES-HMB group showed significantly decreased SFAs (C17:0 and C18:0) (p < 0.05) and significantly increased MUFAs (C15:1N5 and C18:1N9) and PUFAs (C18:2N6, C18:3N6, C18:3N3, C20:3N6, and C20:3N3) (p < 0.05). …”
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21049
H2AK119ub is neurodevelopmentally enriched within H3K9ac-positive euchromatin.
Published 2025“…(F) Heatmaps depicting H3K9ac CUT&RUN data within loci with no change, increased or decreased H2AK119ub over neurodevelopment. (G) Heatmaps depicting H3K9ac CUT&RUN data within loci harboring both H2AK119ub and H3K27me3. …”
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21050
Table1_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.docx
Published 2024“…Finally, among septic patients, decreased total TNF and IFNγ expression were associated with 180-day mortality.…”
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21051
Image2_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.jpeg
Published 2024“…Finally, among septic patients, decreased total TNF and IFNγ expression were associated with 180-day mortality.…”
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21052
Data Sheet 1_Endophytic and antagonistic Bacillus amyloliquefaciens 8SE-IF1-derived nanoparticles encumber phytopathogenic oomycetes, fungi, bacteria, and viruses with enhanced gro...
Published 2025“…The water-diffusible extract (WDE) of Ba-8SE-IF1 significantly inhibited the mycelial growth of Pythium aphanidermatum (44.6%), Phytophthora nicotianae (60.1%), Fusarium oxysporum f. sp. lycopersici (65.5%), and Colletotrichum gloeosporioides (66.7%) in poisoned food assays; the growth of Ralstonia solanacearum and Xanthomonas campestris in the agar well method (inhibition zones of 20.25 mm and 28.52 mm, respectively); and decreased the symptoms produced by tomato spotted wilt virus (TSWV) in local lesion host (68.3%) and tomato leaf curl New Delhi virus (ToLCNDV) in tomato plants (66.1%). …”
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21053
Image3_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.jpeg
Published 2024“…Finally, among septic patients, decreased total TNF and IFNγ expression were associated with 180-day mortality.…”
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21054
Image1_Surviving septic patients endotyped with a functional assay demonstrate active immune responses.jpeg
Published 2024“…Finally, among septic patients, decreased total TNF and IFNγ expression were associated with 180-day mortality.…”
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21055
Time-limited downregulation of cerebellar neurophysiological processes in NHPs during LACV infection.
Published 2025“…The color scale is based on the significance (-log<sub>10</sub> p-adj). The gene ontology (GO) sources: BP, Biological Process; CC, Cellular Component; and MF, Molecular Function (terms are highlighted by respective colors). …”
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21056
Data Sheet 1_OvaRePred (HerTempo): an enhanced ovarian aging clock for personalized reserve assessment, endocrine age modeling, and predicting reproductive milestones across the fe...
Published 2025“…AMH sampling on different cycle days showed only modest effects from minor fluctuations; only substantial AMH decreases significantly affected prediction accuracy. …”
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21057
Table 1_Determining the efficacy and safety of acupuncture for the treatment of menstrual migraine: an updated systematic review and meta-analysis.docx
Published 2025“…Compared with control interventions, acupuncture significantly reduced VAS scores, decreased the frequency and duration of migraine attacks, and improved response rates, as well as HIT-6 and MHI scores. …”
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21058
Image 1_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.tif
Published 2025“…</p>Results<p>Polygonatum sibiricum polysaccharides significantly improved zebrafish swimming behavior, reduced blood glucose and fructosamine levels, and enhanced ATP production (p < 0.01). …”
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21059
Table 1_Avoiding touching until 60 min—contamination of transdermal estradiol gel after physical contact.docx
Published 2025“…In the estradiol gel group, estradiol levels remained stable within the first 30 min (p >0.05), rapidly decreased at 60 min (p <0.001) and remained stable from 60 min to 120 min (p >0.05). …”
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21060
List of primers used in quantitative RT-PCR.
Published 2025“…The results demonstrated that NPs significantly reduced basal rot symptoms and decreased the Area Under the Disease Progress Curve (AUDPC) values. …”