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20361
Table 4_Global, regional, and national analyses of the burden among adult women of breast cancer attributable to diet high in red meat from 1990 to 2021: longitudinal observational...
Published 2025“…In high SDI regions, age-standardized mortality (−1.47%) and DALYs (−1.48%) rates declined, while low-middle and high-middle SDI regions showed significant increases. Low SDI regions, despite lower absolute numbers, experienced sharp relative increases in both deaths and DALYs. …”
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20362
Image 2_Global, regional and national burden of diabetes mellitus type 2 attributable to low physical activity from 1990 to 2021 and projections to 2050: a finding from the global...
Published 2025“…</p>Result<p>In 2021, T2DM attributed to low physical activity caused 149,214 deaths and 5,523,050 DALYs, with significant increases since 1990. Both age-standardized mortality rate (ASMR) and age-standardized disability-adjusted life years (DALYs) rate (ASDR) rose, especially among females. …”
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20363
Image 12_Global, regional and national burden of diabetes mellitus type 2 attributable to low physical activity from 1990 to 2021 and projections to 2050: a finding from the global...
Published 2025“…</p>Result<p>In 2021, T2DM attributed to low physical activity caused 149,214 deaths and 5,523,050 DALYs, with significant increases since 1990. Both age-standardized mortality rate (ASMR) and age-standardized disability-adjusted life years (DALYs) rate (ASDR) rose, especially among females. …”
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20364
Image 4_Global, regional and national burden of diabetes mellitus type 2 attributable to low physical activity from 1990 to 2021 and projections to 2050: a finding from the global...
Published 2025“…</p>Result<p>In 2021, T2DM attributed to low physical activity caused 149,214 deaths and 5,523,050 DALYs, with significant increases since 1990. Both age-standardized mortality rate (ASMR) and age-standardized disability-adjusted life years (DALYs) rate (ASDR) rose, especially among females. …”
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20365
Supplementary Material for: Exploratory Analysis of Sleep Deprivation Effects on Gene Expression and Regional Brain Metabolism
Published 2025“…For brain metabolism, sleep deprivation resulted in significant decreases in the left insula, left medial prefrontal cortex (BA32), left somatosensory cortex (BA1/2), and left motor premotor cortex (BA6) and increases in the right inferior longitudinal fasciculus, right primary visual cortex (BA17), right amygdala, left cerebellum, and bilateral pons. …”
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20366
Supplementary file 1_Persistent burden and health inequalities of disease in women of childbearing age attributable to Intimate Partner Violence, 1990–2021.docx
Published 2025“…The absolute value of the SII for ASMR increased from 2.04 in 1990 to 4.59 in 2021, while that of the SII for ASDR decreased from 321 in 1990 to 190 in 2021. …”
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20367
Image 1_China’s colorectal cancer burden and dietary risk factors: a temporal analysis (1990–2021).pdf
Published 2025“…The estimated annual percentage change (EAPC) trends were assessed.</p>Results<p>In 2021, China had 658321.36 new CRC cases (315.63% increase vs. 1990) and 275129.23 deaths (130.61% increase), with males showing greater burden increases. …”
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20368
Data Sheet 1_Burden and trends of ovarian and uterine cancer due to high body mass index from 1990 to 2021: an age–period–cohort study based on the GBD 2021, and projections throug...
Published 2025“…From 1990 to 2021, ASRs for mortality and DALYs for both OC and UC attributable to high BMI significantly increased and are projected to continue rising over the next 15 years. …”
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20369
Table 1_China’s colorectal cancer burden and dietary risk factors: a temporal analysis (1990–2021).pdf
Published 2025“…The estimated annual percentage change (EAPC) trends were assessed.</p>Results<p>In 2021, China had 658321.36 new CRC cases (315.63% increase vs. 1990) and 275129.23 deaths (130.61% increase), with males showing greater burden increases. …”
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20370
Table 1_Global disease burden of colorectal cancer attributable to high BMI has more than doubled over the past 30 years.xlsx
Published 2025“…Trends in age-standardized death rates (ASDR) and disability-adjusted life-years (DALYs) were assessed using the estimated annual percentage change (EAPC).</p>Results<p>Between 1990 and 2021, CRC deaths attributable to obesity increased from 41,535.8 (95% UI 17,665.6–67,379) to 99,268.0 (95% UI 42,956.3–157,948.8), while DALYs increased from 15,042.1 (95% UI 4,297.8–16,319.7) to 64,664.2 (95% UI 102,159.3–375,234.0). …”
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20371
Human disturbance facilitates the environmental dependence of biodiversity-ecosystem multifunctionality relationship across spatial scales in temperate forests
Published 2025“…<p dir="ltr">The relationship between biodiversity and ecosystem multifunctionality (BEMF) is environmentally dependent under global climate change, and increasing human disturbance may affect this dependence. …”
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20372
Image 3_Low CD46 expression on activated CD4+ T cells predict improved Th1 cell reactivity to calcitriol in majority of patients with allergic eosinophilic asthma and healthy donor...
Published 2024“…The calcitriol-induced regulatory effect manifested by a stronger surface decrease of CD46 on activated CD4<sup>+</sup> T cells (by 40% in HDs and by 26% in AEA), accompanied by a significant inhibition of IFN-γ and increased IL-10 production (by 31% in HDs and by 85% in AEA). …”
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20373
Image 1_Low CD46 expression on activated CD4+ T cells predict improved Th1 cell reactivity to calcitriol in majority of patients with allergic eosinophilic asthma and healthy donor...
Published 2024“…The calcitriol-induced regulatory effect manifested by a stronger surface decrease of CD46 on activated CD4<sup>+</sup> T cells (by 40% in HDs and by 26% in AEA), accompanied by a significant inhibition of IFN-γ and increased IL-10 production (by 31% in HDs and by 85% in AEA). …”
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20374
Image 4_Low CD46 expression on activated CD4+ T cells predict improved Th1 cell reactivity to calcitriol in majority of patients with allergic eosinophilic asthma and healthy donor...
Published 2024“…The calcitriol-induced regulatory effect manifested by a stronger surface decrease of CD46 on activated CD4<sup>+</sup> T cells (by 40% in HDs and by 26% in AEA), accompanied by a significant inhibition of IFN-γ and increased IL-10 production (by 31% in HDs and by 85% in AEA). …”
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20375
Image 2_Low CD46 expression on activated CD4+ T cells predict improved Th1 cell reactivity to calcitriol in majority of patients with allergic eosinophilic asthma and healthy donor...
Published 2024“…The calcitriol-induced regulatory effect manifested by a stronger surface decrease of CD46 on activated CD4<sup>+</sup> T cells (by 40% in HDs and by 26% in AEA), accompanied by a significant inhibition of IFN-γ and increased IL-10 production (by 31% in HDs and by 85% in AEA). …”
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20376
Data Sheet 1_Low CD46 expression on activated CD4+ T cells predict improved Th1 cell reactivity to calcitriol in majority of patients with allergic eosinophilic asthma and healthy...
Published 2024“…The calcitriol-induced regulatory effect manifested by a stronger surface decrease of CD46 on activated CD4<sup>+</sup> T cells (by 40% in HDs and by 26% in AEA), accompanied by a significant inhibition of IFN-γ and increased IL-10 production (by 31% in HDs and by 85% in AEA). …”
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20377
Table 1_Socio-hydrology and sustainable tank management: empirical case from a Mailam tank cascade, Tamil Nadu, India.xlsx
Published 2025“…The dependence on tanks for irrigation by farmers in the study area has decreased, ranging from 9 to 54%. There has been a significant change in land use; a 44% reduction in the area under cropping (1,707 ha to 954 ha), with a 13% increase in fallow land (1,607 ha to 1,822 ha) and a 43% increase in other vegetation and built-up area from 5 ha to 60 ha. …”
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20378
Data Sheet 1_Developing emotional intelligence and counseling self-efficacy in clinical pastoral education in healthcare settings: a multicenter pre-post study.pdf
Published 2025“…EI gains significantly predicted CSE improvements for both groups, with moderate correlations between EI and CSE changes. …”
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20379
Data Sheet 1_Global, regional, and national burden of Pediatric and adolescent thyroid cancer from 1990 to 2021: a statistical analysis of prevalence, incidence, and DALYs.zip
Published 2025“…It assessed the evolving trends in the burden of thyroid cancer among children and adolescents by employing the EAPC (Estimated Annual Percentage Change) and percentage change metric.</p>Results<p>In 2021, the global prevalence, incidence, and disability-adjusted life-years of pediatric and adolescent thyroid cancer reached 91,313 cases, 10,137 cases, and 60,185 years respectively. …”
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20380
Data Sheet 1_Evolving trends and burden of idiopathic epilepsy among children (0–14 years), 1990–2021: a systematic analysis for the Global Burden of Disease study 2021.zip
Published 2025“…Joinpoint regression analyses assessed changes over time, calculating average annual percentage change (AAPC) statistics. …”