Hypoxia-inducible factor-1α promotes tubulointerstitial fibrosis via the upregulation of <i>Muc4</i> by Zhong-Tang Li (21183172)

“…Then, the results of transcriptomic analysis and <i>in vivo</i> and <i>in vitro</i> experiments revealed that expression of Mucin 4 (MUC4) was significantly decreased at the transcriptional and protein levels in tubular HIF-1α-knockout mice. …”

Pan-cancer analysis reveals PRRT4 is a potential prognostic factor of AML by Wenqiong Xiang (17738962)

“…After PRRT4 knockdown, the proliferation ability of THP1 cells was significantly enhanced, and the apoptosis ratio was significantly decreased.…”

Learning-related changes in assembly–reader relations. by Marco N. Pompili (12288422)

“…Assembly–reader pairs above the higher dashed line (respectively, below the lower dashed line) significantly (<i>p</i> < 0.05, Monte–Carlo bootstrap test) increased (respectively, decreased) their responses in post-task sleep. …”

Image 2_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.tiff by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Table 1_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.xlsx by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

DataSheet1_Apolipoprotein A-I attenuates peritoneal fibrosis associated with peritoneal dialysis by inhibiting oxidative stress and inflammation.ZIP by Jing Lu (120666)

“…In this study, by analyzing PD patients (n = 81), we found that decreased apoA/HDL-C ratio is significantly associated with rapid decline in peritoneal function. …”

Image 1_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.tiff by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Image 4_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.tiff by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Image 5_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.tif by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Data Sheet 1_Characterization of peripheral immune cells in kidney transplantation recipients under different immunosuppressive treatments.docx by Yunze Tai (21522872)

“…</p>Results<p>In KTRs, the expression of G-MDSCs and M-MDSCs was significantly higher than the HCs, while the expression of HLA-DR⁺ monocytes, CD38⁺/CD28⁺ activated T cells, CD4⁺ naïve T cells, CD4⁺ effector memory T cells, and central memory T cells were significantly lower. …”

Image 3_The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis.tiff by Qitian Zhang (19791372)

“…Four distinct FB trajectory patterns were identified, Trajectory 1 (rapid transition to negative balance), Trajectory 2 (stable balance), Trajectory 3 (positive balance gradually decreasing), and Trajectory 4 (decreasing at a high level). …”

Data Sheet 1_Multimodal MRI reveals distinct hippocampal subregional alterations in de novo Parkinson’s disease across the cognitive spectrum.docx by Chenxi Pan (10211363)

“…</p>Results<p>Compared to the PD-NC, the PD-SCD group revealed a significantly decreased FC between the left middle hippocampus (HIPm) and right postcentral gyrus (PoCG. …”

Functional predictions and abundance top 15. by Xia Deng (613144)

“…The FUN Guild prediction showed that six groups of plant pathogens and plant saprotrophs changed significantly (<i>P <</i> 0.05), the amount of harmful bacteria in the soil increased while the amount of arbuscular mycorrhizal fungui (AMF) decreased, leading to a continuous cropping obstacle of lavender. …”

Impact of Gemin5 in protein synthesis: phosphoresidues of the dimerization domain regulate ribosome binding by Salvador Abellan (19499424)

“…In addition, ribosome binding decreased when Ser/Thr 847 and 852–854 are substituted by a non-phosphorylatable residue, consistent with decreased protein stability, and reduced number of associated factors. …”

Data Sheet 1_Alpha-synuclein knockout impairs melanoma development and alters DNA damage repair in the TG3 mouse model in a sex-dependent manner.docx by Moriah R. Arnold (20908868)

“…Furthermore, decreased tumor volume is correlated with a decreased DNA damage signature and increased apoptotic markers, indicating a role for αSyn in modulating the DNA damage response (DDR) pathway. …”

Supplementary file 1_Longitudinal assessment of oral and gut microbiome overlap in patients with Alcohol Use Disorder undergoing inpatient treatment.docx by Jennifer J. Barb (9153014)

“…Results indicated that the oral and gut microbiomes became less similar during the first week of treatment, with both the number of shared genera and Sorenson-Dice Index values decreasing significantly (p <.001). However, the Robust Aitchison Distance also decreased over time (p <.05), suggesting increased compositional similarity among the shared genera. …”

Table 2_Longitudinal assessment of oral and gut microbiome overlap in patients with Alcohol Use Disorder undergoing inpatient treatment.csv by Jennifer J. Barb (9153014)

“…Results indicated that the oral and gut microbiomes became less similar during the first week of treatment, with both the number of shared genera and Sorenson-Dice Index values decreasing significantly (p <.001). However, the Robust Aitchison Distance also decreased over time (p <.05), suggesting increased compositional similarity among the shared genera. …”

Data Sheet 1_Knockdown of annexin A2 enhances the host cell apoptosis induced by Eimeria tenella.zip by Jixia Wang (1685902)

“…Following ANXA2 knockdown, the cell apoptosis rate, caspase-3 activity, and Bax expression levels were significantly increased (P < 0.01), whereas the infection rate and Bcl-2 expression levels were significantly decreased (P < 0.01) compared to the group infected with E. tenella alone. …”

Image 1_First-trimester choroid plexus-to-head ratio: a novel sonographic marker for the early detection of fetal central nervous system malformations.jpeg by Xianghua Xue (22563098)

“…Compared with the control group, scatter diagrams and box-and-whiskers plots showed ventriculomegaly (VM) fetuses had significantly decreased CPA/HA and CPL/OFD ratios (p < 0.001), but increased CFD/OFD and HC/AC ratios (p < 0.001). …”

Image 2_First-trimester choroid plexus-to-head ratio: a novel sonographic marker for the early detection of fetal central nervous system malformations.jpeg by Xianghua Xue (22563098)

“…Compared with the control group, scatter diagrams and box-and-whiskers plots showed ventriculomegaly (VM) fetuses had significantly decreased CPA/HA and CPL/OFD ratios (p < 0.001), but increased CFD/OFD and HC/AC ratios (p < 0.001). …”