First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

Data Sheet 1_Differentiated response mechanisms of soil microbial communities to nitrogen deposition driven by tree species variations in subtropical planted forests.docx by Zheng Hou (67780)

“…</p>Results and discussion<p>The results showed that species differences led to variations in soil properties between the two forests, particularly a significant increase in soil pH in P. yunnanensis Franch. forests and a significant decrease in soil pH in P. armandii Franch. forests. …”

Clinical data of lymphoma patients. by Runlong Lin (20796909)

“…Moreover, the count of patients with abnormal cardiac uptake significantly rose post-treatment. Analyzing changes in uptake patterns, the group displaying abnormal changes exhibited an increase in left atrial diameter and a decrease in left ventricular ejection fraction compared to the group with normal changes. …”

Contribution of Chloride to Salty Taste in Gustatory Sensation by Miku Nakagai (21015162)

“…When amiloride was added, the saltiness intensities of sodium salts decreased significantly, whereas those of chloride salts did not decrease. …”

Supplementary Material 4–DMSO does not alter zebrafish motility at concentrations below 1%. by Geyse Gomes (22075629)

“…No significant alterations in embryos motility were observed, although a dose-dependent tendency of decrease in locomotion was observed. …”

The dataset for Aerosol emission reductions cause post-2011 rapid warming in the northwestern Pacific. by Nan Yang (22539191)

“…Aerosol-driven ocean warming manifests a five-year lag post-emission reductions, governed by threshold-triggered nonlinear aerosol-cloud interaction where cloud decrease occurs only below critical aerosol thresholds (AOD = 0.2). …”

TLR4 is involved in the VCC-induced activation of BMDCs. by Shraddha Gandhi (21001590)

“…Immunoblots shown here are the representatives of three independent experiments. (E-F) Significant decrease in the VCC-mediated IL-6 production in BMDCs, upon pre-neutralization of TLR4 with anti-TLR4 antibody. …”

Table 1_New serum soluble factors predicting inflammatory and non-inflammatory disability worsening in multiple sclerosis.doc by Alexander Rodero-Romero (20172186)

“…Q-values below 0.05 were considered as significant.</p>Results<p>Compared with HC, patients with low sGFAP concentrations exhibited decreased levels of granulocyte-macrophage colony stimulating factor (GM-CSF), a cytokine inducing innate cell activation q=0.009 for NLGL and q=0.002 for NHGL groups). …”

Impact of environmental temperature on daily brood sizes across species. by Ben T. Gregory (20442502)

“…<i>elegans</i> adults showed a significant decrease in brood size on day 1. n = 31–54 adult worms. ns = not significant, ****<i>p</i><0.0001, two-way ANOVA with Tukey’s multiple comparisons test.…”

Data Sheet 1_Quantitative EEG and its relationship with attentional control in patients with anxiety disorders.docx by Danfeng Yuan (12068884)

“…Additionally, a significant decrease in temporal beta power was observed in the ANX group. …”

Supplementary Material for: Temporal trends of pediatric stroke burden attributable to non-optimal temperature in the United States, 1990-2019: An analysis for the Global Burden of... by figshare admin karger (2628495)

“…R and Joinpoint were used to conduct the statistical analyses in this study. A p-value <0.05 was considered statistically significant. …”