Data Sheet 4_N6-methyladenosine RNA landscape in the aged mouse hearts.pdf by Xia Jing (3255219)

“…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H₂O₂-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …”

Table 3_Global, regional, and national burden of acute hepatitis (1990–2021): a systematic analysis of the global burden of disease in 2021.xlsx by Zhixun Bai (14021787)

“…</p>Conclusion<p>While global AVH burden is decreasing, significant disparities persist, warranting tailored interventions to enhance resource equity in high-SDI regions and strengthen healthcare infrastructure in low-SDI areas.…”

Table 2_Global, regional, and national burden of acute hepatitis (1990–2021): a systematic analysis of the global burden of disease in 2021.xlsx by Zhixun Bai (14021787)

“…</p>Conclusion<p>While global AVH burden is decreasing, significant disparities persist, warranting tailored interventions to enhance resource equity in high-SDI regions and strengthen healthcare infrastructure in low-SDI areas.…”

Table 1_Global, regional, and national burden of acute hepatitis (1990–2021): a systematic analysis of the global burden of disease in 2021.docx by Zhixun Bai (14021787)

“…</p>Conclusion<p>While global AVH burden is decreasing, significant disparities persist, warranting tailored interventions to enhance resource equity in high-SDI regions and strengthen healthcare infrastructure in low-SDI areas.…”

PRISMAS flowchart of the screening process. by Xianghong Hu (17966261)

“…</p><p>Conclusions</p><p>The available evidence indicates that preoperative PENG block can significantly decrease opioid consumption and pain early after hip surgery, and it may also promote early functional rehabilitation. …”

Image_1_Dietary soy protein reverses obesity-induced liver steatosis and alters fecal microbial composition independent of isoflavone level.JPEG by Reza Hakkak (11086)

“…HIF) did not affect any of these measurements except in the SPC-HIF group, which had an additional decrease in liver weight (p < 0.05) compared to the SPC-LIF group. …”

Data Sheet 1_Exploring the glucose-lowering and anti-inflammatory immune mechanism of artemether by AMPK/mTOR pathway and microbiome based on multi-omics.docx by Tao Jiang (28401)

“…</p>Results<p>ATM treatment (160 mg/kg) observably ameliorated insulin resistance (IR), hyperglycemia, hyperlipemia and pathological injury in the liver and pancreas. In addition, ATM significantly decreased the expression of TNF-α, IL-1β, IL-6, NF-κB and IL-17A, and significantly increased the level of IL-10 in diabetic mice. 16S rRNA sequencing and targeted GC-MS metabolomics result indicated that ATM restored gut microbiota dysbiosis based on increasing beneficial bacteria Lactobacillus and reducing pathogenic bacteria Helicobacter and Prevotella leading to the accumulation of propionic and valeric acids and the reduction of lipopolysaccharides (LPS) release, intestinal inflammation and intestinal barrier damage. …”

Table_1_Dietary soy protein reverses obesity-induced liver steatosis and alters fecal microbial composition independent of isoflavone level.DOCX by Reza Hakkak (11086)

“…HIF) did not affect any of these measurements except in the SPC-HIF group, which had an additional decrease in liver weight (p < 0.05) compared to the SPC-LIF group. …”

Data Sheet 1_Combination of Sodium Butyrate and Immunotherapy in Glioma: regulation of immunologically hot and cold tumors via gut microbiota and metabolites.docx by Sui Li (8872481)

“…Moreover, metabolites produced by the gut microbiota can significantly impact both systemic immune responses and central nervous system (CNS) immunity. …”

Assessment of calcium events, pERK levels, NMDA receptor expression and extracellular zinc levels in <i>slc13a5</i> mutants. by Deepika Dogra (21072023)

“…<i>5a</i>^{<i>−/−</i>}<i>;5b</i>^{<i>−/−</i>} larvae show a significant decrease in Palm-ZP1:CellMask Orange CTCF ratio in the plasma membrane compared to WTs. …”

Image 4_Serum neuritin as a predictive biomarker of early neurological deterioration and poor prognosis after spontaneous intracerebral hemorrhage: a prospective cohort study.tif by Yanwen Xu (663813)

“…END was defined as a decrease of ≥2 points in the GCS score within 24 h of admission. …”

Table 2_Epidemiology of second trimester induced abortion in Ethiopia: a systematic review and meta-analysis.docx by Mesfin Abebe (12400154)

“…The findings highlight the urgent need for targeted interventions to address these factors and decrease the incidence of second-trimester abortions. …”

Image 6_Serum neuritin as a predictive biomarker of early neurological deterioration and poor prognosis after spontaneous intracerebral hemorrhage: a prospective cohort study.tif by Yanwen Xu (663813)

“…END was defined as a decrease of ≥2 points in the GCS score within 24 h of admission. …”

Supplementary file 2_Histopathological examination and transcriptomic profiling reveal gossypol toxicity-responsive genes related to fertility in mice.docx by Teame Gereziher Mehari (11253141)

“…Routine blood tests revealed significantly elevated neutrophil granulocytes and monocytes, along with a marked decrease in lymphocytes. …”

Table 1_Unexpected estradiol decline during ovarian stimulation monitoring affects cumulative live birth.docx by Haixiao Chen (12565087)

“…In both unmatched and matched cohorts, the CLBRs were significantly decreased (unmatched cohort: 66.3% versus 55%, P<0.001, adjusted OR 0.83, 95% CI: 0.76,0.91; matched cohort: 59% versus 55%, P = 0.003, adjusted OR 0.84, 95%CI: 0.75,0.94). …”

Image 3_Serum neuritin as a predictive biomarker of early neurological deterioration and poor prognosis after spontaneous intracerebral hemorrhage: a prospective cohort study.tif by Yanwen Xu (663813)

“…END was defined as a decrease of ≥2 points in the GCS score within 24 h of admission. …”

Image 7_Serum neuritin as a predictive biomarker of early neurological deterioration and poor prognosis after spontaneous intracerebral hemorrhage: a prospective cohort study.tiff by Yanwen Xu (663813)

“…END was defined as a decrease of ≥2 points in the GCS score within 24 h of admission. …”

Data Sheet 1_Effects of sodium tanshinone IIA sulfonate injection on pro-inflammatory cytokines, adhesion molecules and chemokines in Chinese patients with atherosclerosis and athe... by Fan Xie (562816)

“…</p>Conclusion<p>The use of STS in patients with AS and ASCVD appeared to significantly decrease levels of pro-inflammatory cytokines, adhesion molecules, and chemokines.…”

Data Sheet 1_Retroperitoneal fibrosis in presence of autoimmune coagulation factor XIII deficiency result in recurrent critical post-operative hemorrhage: a case report and molecul... by Tomonori Matsushita (1682554)

“…Background<p>Idiopathic retroperitoneal fibrosis is an IgG4-related disease where pathological role and clinical significance of IgG4 antibodies remain largely unknown. …”

Data Sheet 1_ESAT-6 protein suppresses allograft rejection by inducing CD4+Foxp3+ regulatory T cells through IκBα/cRel pathway.docx by Xiaofei Huang (2262337)

“…Moreover, it suppressed conventional CD4⁺CD25^- T cell proliferation in vitro in the absence of antigen-presenting cells (APCs), with an increase in IL-10 and decrease in IFN-γ production. On the other hand, it did not significantly alter DC maturation after allotransplantation.…”