Deleterious Effects of a GAD65 Monoclonal Autoantibody on Islet Function by Christiane S. Hampe (248347)

“…<p dir="ltr">An intrinsic hallmark of Type 1 Diabetes is the correlation between appearance of autoantibodies directed against islet cell autoantigens with subsequent development of the disease. We recently studied effects of human monoclonal autoantibodies (mAb) derived from a pre-diabetic patient and demonstrated that a GAD65mAb penetrated and accumulated in beta cells and significantly reduced the insulin secretion rate (ISR). …”

Supplementary Material for: Construction of a hybrid vaccine based on Der f 35-derived peptides with reduced allergenicity by Hu H. (4145581)

“…The levels of IL-5 and IL-13 from PBMCs were significantly decreased after stimulation by the vaccine than that by Der f 35 (p < 0.05). …”

Table 1_Association of cardiovascular health with reproductive lifespan and pregnancy loss: insights from NHANES 2005–2018.pdf by Yang Yan (222441)

“…Since the cardiovascular system delivers oxygen, nutrients, and hormones throughout the body, cardiovascular health (CVH) may significantly impact hormonally controlled events such as pregnancy, menarche, and menopause. …”

Table 2_Association of cardiovascular health with reproductive lifespan and pregnancy loss: insights from NHANES 2005–2018.docx by Yang Yan (222441)

“…Since the cardiovascular system delivers oxygen, nutrients, and hormones throughout the body, cardiovascular health (CVH) may significantly impact hormonally controlled events such as pregnancy, menarche, and menopause. …”

Figure S1-S21 from miR-196b-5p Regulates Colorectal Cancer Cell Migration and Metastases through Interaction with HOXB7 and GALNT5 by Verena Stiegelbauer (4582930)

“…The miR-196b-5p inhibited DLD1 cells closed the scratch significantly earlier than the inhibitor control cells, whereas the miR-196b-5p overexpression in SW480 resulted in decreased scratch closure (* = significant, p < 0.05; **, p < 0.01; ***, p < 0.001; studentÂ's t-test). …”

Data Sheet 1_The CENPN/STAT3/USP37 signaling axis promotes invasion, migration and metastasis in nasopharyngeal carcinoma.docx by Yu-Fei Wang (322119)

“…</p>Results<p>The invasion and migration capacities of nasopharyngeal carcinoma cells decreased significantly after CENPN knockdown, whereas the overexpression of CENPN significantly promoted the invasion and metastasis abilities of nasopharyngeal carcinoma cells. …”

Table 2_Impact of chemoradiotherapy for first primary lung cancer on the prognosis and re-chemoradiotherapy sensitivity of second primary lung cancer.docx by Zhe Chen (196097)

“…</p>Results<p>The competitive risk model indicated that FPLC radiotherapy and chemotherapy did not significantly change the risk of developing SPLC. However, the Cox proportional hazards model revealed that FPLC radiotherapy was associated with decreased overall survival (OS; HR=1.251, P<0.001) and cancer-specific survival (CSS; HR=1.228, P=0.001) in patients with SPLC. …”

Data Sheet 1_Patient engagement in radiation oncology: a large retrospective study of survey response dynamics.docx by Bailey A. Loving (20573882)

“…MVA showed that higher socioeconomic disadvantage significantly decreased survey participation (ADI third tertile vs. first tertile OR=0.708, p<0.001), with each unit increase in ADI reducing the odds of completion by 1% (p<0.001). …”

Data Sheet 1_Impact of chemoradiotherapy for first primary lung cancer on the prognosis and re-chemoradiotherapy sensitivity of second primary lung cancer.xlsx by Zhe Chen (196097)

“…</p>Results<p>The competitive risk model indicated that FPLC radiotherapy and chemotherapy did not significantly change the risk of developing SPLC. However, the Cox proportional hazards model revealed that FPLC radiotherapy was associated with decreased overall survival (OS; HR=1.251, P<0.001) and cancer-specific survival (CSS; HR=1.228, P=0.001) in patients with SPLC. …”

Table 3_Impact of chemoradiotherapy for first primary lung cancer on the prognosis and re-chemoradiotherapy sensitivity of second primary lung cancer.docx by Zhe Chen (196097)

“…</p>Results<p>The competitive risk model indicated that FPLC radiotherapy and chemotherapy did not significantly change the risk of developing SPLC. However, the Cox proportional hazards model revealed that FPLC radiotherapy was associated with decreased overall survival (OS; HR=1.251, P<0.001) and cancer-specific survival (CSS; HR=1.228, P=0.001) in patients with SPLC. …”

DataSheet1_HER2 expression in different cell lines at different inoculation sites assessed by [52Mn]Mn-DOTAGA(anhydride)-trastuzumab.docx by Toàn Minh Ngô (21195116)

“…The ratios for orthotopic HER2-positive tumors were significantly higher than those for ectopic HER2-negative tumors and melanoma at all time points. …”

Table 1_Microbial diversity and community assembly in heavy metal-contaminated soils: insights from selenium-impacted mining areas.xlsx by Zhiyong Wang (313131)

“…Heavy metal pollution significantly impacts soil microbial communities due to its persistence and long-term residual effects. …”

Data Sheet 1_High spatial resolution gene expression profiling and characterization of neuroblasts migrating in the peri-injured cortex using photo-isolation chemistry.docx by Takuya Miyamoto (567070)

“…Experiments using primary cultured neuroblasts showed that application of TGF-β significantly decreased proliferating cells labeled with BrdU. …”

Table 1_Impact of chemoradiotherapy for first primary lung cancer on the prognosis and re-chemoradiotherapy sensitivity of second primary lung cancer.docx by Zhe Chen (196097)

“…</p>Results<p>The competitive risk model indicated that FPLC radiotherapy and chemotherapy did not significantly change the risk of developing SPLC. However, the Cox proportional hazards model revealed that FPLC radiotherapy was associated with decreased overall survival (OS; HR=1.251, P<0.001) and cancer-specific survival (CSS; HR=1.228, P=0.001) in patients with SPLC. …”

Table 2_Microbial diversity and community assembly in heavy metal-contaminated soils: insights from selenium-impacted mining areas.docx by Zhiyong Wang (313131)

“…Heavy metal pollution significantly impacts soil microbial communities due to its persistence and long-term residual effects. …”

Data Sheet 1_Genetic variation in RYR1 is associated with heart failure progression and mortality in a diverse patient population.docx by Leonardo A. Guerra (20762270)

“…Based on eQTL data, these SNPs were associated with decreased RYR1 expression in vascular tissue. Two missense variants, in linkage disequilibrium with rs2915950 (rs2915952 and rs2071089) were significantly associated with decreased mortality risk (P = 0.03) and decreased risk of atrial fibrillation/flutter (OR: 0.66, 95% CI: 0.44–0.96; P = 0.03 and OR: 0.67, 95% CI: 0.45–0.98; P = 0.04, respectively). …”

GI variables of single-task versus dual-task. by Angeloh Stout (21755757)

“…We found that dual-task conditions significantly affected both gait initiation and sit-to-walk patterns, increasing the duration of transitions and mediolateral center of mass displacements, while reducing vertical center of mass displacements and forward propulsion. …”

STW variables of single-task versus dual-task. by Angeloh Stout (21755757)

“…We found that dual-task conditions significantly affected both gait initiation and sit-to-walk patterns, increasing the duration of transitions and mediolateral center of mass displacements, while reducing vertical center of mass displacements and forward propulsion. …”

Image 10_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg by Chen Wang (88408)

“…Additionally, we evaluated tumor growth and immune cell infiltration using syngeneic mouse models.…”

DataSheet8_Refining dual RNA-seq mapping: sequential and combined approaches in host-parasitic plant dynamics.csv by Carmine Fruggiero (20143830)

“…However, it has to deal with issues related to multiple mapping and cross-mapping of reads in host and parasite genomes, particularly as evolutionary divergence decreases. In this paper, we evaluated the feasibility of this technique by simulating interactions between parasitic and host plants and refining the mapping process. …”