Supplementary file 1_Dietary α-sitosterol mitigates titanium dioxide nanoparticle-induced hemato-immunotoxicity, oxidative stress, and gene expression dysregulation in Oreochromis... by Amany Behairy (22658510)

“…Furthermore, STL significantly decreased elevated serum alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, urea, and creatinine levels induced by TDNPs, and normalized lipid profiles by reducing total cholesterol, triglycerides, and low-density lipoprotein cholesterol, while elevating high-density lipoprotein cholesterol. …”

Data Sheet 1_Dietary α-sitosterol mitigates titanium dioxide nanoparticle-induced hemato-immunotoxicity, oxidative stress, and gene expression dysregulation in Oreochromis niloticu... by Amany Behairy (22658510)

“…Furthermore, STL significantly decreased elevated serum alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, urea, and creatinine levels induced by TDNPs, and normalized lipid profiles by reducing total cholesterol, triglycerides, and low-density lipoprotein cholesterol, while elevating high-density lipoprotein cholesterol. …”

Uncovering the mechanistic basis of <i>Rheum palmatum</i> L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular doc... by Wenjing He (4278625)

“…MR analysis demonstrated a statistically significant causal association between TNF and CKD (OR = 1.02, <i>p</i> < 0.05), with positive trends for IL6 and CASP3. …”

Data Sheet 1_Population pharmacokinetics/pharmacodynamics and safety of YPEG-rhGH in elderly subjects.docx by Yajie He (20323682)

“…In the final model, AGE was identified as a significant covariate for K_a, V₁/F, and V_max, while WEIGHT significantly influenced V_max. …”

Data Sheet 1_Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.xlsx by Yu Chen (29959)

“…Interestingly, NcGRA7 formed a complex with the prohibitins PHB1 and PHB2. Using inhibitors of PHB1 or transfecting N. caninum-infected THP-1 cells with PHB1 siRNA significantly decreased IL-1β production, but not TNF-α.…”

Table 1_Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.docx by Yu Chen (29959)

“…Interestingly, NcGRA7 formed a complex with the prohibitins PHB1 and PHB2. Using inhibitors of PHB1 or transfecting N. caninum-infected THP-1 cells with PHB1 siRNA significantly decreased IL-1β production, but not TNF-α.…”

Table 1_Effect of simulated acidification on soil properties and plant nutrient uptake of eggplant in greenhouse.docx by Tianqi Wang (4093009)

“…Thus, it decreases crop yield. However, there has been a lack of systematic research on how soil acidification influences nutrient absorption in eggplant cultivated in greenhouse. …”

The interaction of COVID-19 and sociodemographic factors on pediatric rehabilitation service initiation by Lynn R. Tanner (21311527)

“…</p> <p>During COVID, service initiation decreased significantly by 23% (<i>p</i> < 0.001), whereas referral rates remained stable. …”

Supplementary Material for: Intermittent Hypoxemia and Neurodevelopmental Impairment at 12 and 24 months in Preterm Infants by figshare admin karger (2628495)

“…In adjusted models, a greater % time <90% and referral scores for communication skills (p=0.0158) at 12 months remained significant. …”

CSF proteins favoring <i>NSE</i> vs <i>HAD</i>. by Zicheng Hu (3825313)

“…For the most part, the protein elevations do not differ significantly, and this volcano plot shows a high degree of protein similarity (or lack of significant differences) within the context of the full complement of measured proteins (identified by simple blue symbols) on each side of the central vertical axis. …”

Presentation 1_Attenuation of cisplatin-induced acute kidney injury by sanguinarine: modulation of oxidative stress, inflammation, and cellular damage.pptx by Nur Elena Zaaba (17891507)

“…Introduction<p>Cisplatin (CP)-induced acute kidney injury (AKI) is a significant side effect of CP chemotherapy, driven by oxidative stress and inflammation. …”

Supplementary file 1_Clinical features of benign paroxysmal positional vertigo in the elderly.docx by Ran Zhou (1450756)

“…</p>Conclusion<p>Compared to the middle-aged BPPV group, elderly patients with BPPV exhibited a higher DHI score, increased fall rates, lower BBS scores, and lower rate maneuver, which had a more significant negative impact on daily life.…”

Table 1_Study on the effect of GCY-12 gene on albendazole sensitivity of Haemonchus contortus by RNA interference.xlsx by Xindi Chen (6485522)

“…Introduction<p>Haemonchus contortus (H. contortus) is a common gastrointestinal nematode in small ruminants, posing a significant threat to the livestock industry. …”

Data Sheet 1_Temporal changes in grain yield and quality of rice varieties released in Guangdong Province, China (1990–2020).docx by Huifang Yang (451937)

“…Temporal analysis showed significant increases in the release of inbred rice, hybrid rice, and high-quality hybrid late rice varieties. …”

Data Sheet 1_Dietary inflammatory index and disability among older adults in Guangzhou: a cross-sectional analysis.pdf by Junbin Liao (4766355)

“…</p>Results<p>Inactivity (never exercising, OR = 8.48, 95% CI = 2.30–31.31) and reduced activity (formerly exercising, OR = 4.85, 95% CI = 1.39–16.96), stroke (OR = 2.78, 95% CI = 1.61–4.80), and dementia (OR = 2.69, 95% CI = 1.26–5.78) were significantly associated with increased disability. After adjusting for confounding factors, a higher DII was linked to a greater degree of disability, with the highest DII quartile showing a notably higher risk (OR = 2.61, 95% CI = 1.21–5.61) compared to the lowest quartile.…”

Plant-based diet and mortality in adults with cardiovascular-kidney-metabolic syndrome: evidence from NHANES with mediation by leukocyte telomere length by Zhuotao Xiao (17355718)

“…Mediation analysis indicated that LTL mediated 7.7, 5.8, and 4.3% of the effect of total PDI, hPDI, and uPDI on all-cause mortality, and 1.3, 1.0, and 8.0% of the effect on CVD mortality, respectively. Thus, greater adherence to a healthful PBD is associated with significantly lower all-cause and CVD mortality in adults with CKM syndrome, an association partially mediated by LTL.…”

Trends and levels of the global, regional, and national burden of injuries from 1990 to 2021: findings from the global burden of disease study 2021 by Jiaqi Lou (17806337)

“…</p> <p>Globally, while absolute numbers of injury incidence, prevalence, deaths, and DALYs increased from 1990 to 2021, all corresponding ASRs declined significantly (EAPC: incidence – 0.96%, prevalence – 0.73%, mortality – 1.55%, and DALYs – 1.75%). …”

Data Sheet 1_Analysis of humoral and cellular immune activation up to 21 months after heterologous and homologous COVID-19 vaccination.docx by Davide Torre (21232373)

“…Antibody titers declined by 12-months post-primary vaccination, regardless of the third dose administered, and increased significantly by 21-months, potentially due to a fourth dose (BNT or mRNA-1273) or natural SARS-CoV-2 infection. …”

Obstructive sleep apnea and polysomnographic predictors of neuropsychological performance two years after injury in a prospective cohort of adults with traumatic brain injury by Marc A. Silva (10360716)

“…Persons with traumatic brain injury (TBI) are at increased risk of OSA compared to community samples, and many experience chronic cognitive disability. …”

Data Sheet 1_A hypoxia-on-a-chip platform for modeling ischemic arrhythmogenesis and evaluating the effects of levosimendan and OR-1896 on ischemic human iPSC-derived cardiomyocyte... by Mahmoud Gaballah (7818905)

“…Hypoxia-induced injury was further assessed by measuring cardiac biomarkers and gene expression profiling of hypoxia-associated pathways. Hypoxia induced significant structural damage, including sarcomere disorganization, mitochondrial cristae fragmentation, and nuclear shrinkage, accompanied by increased release of cardiac biomarkers. …”