Data_Sheet_1_Deregulation of mTORC1-TFEB axis in human iPSC model of GBA1-associated Parkinson’s disease.docx by Fahad Mubariz (16010003)

“…Using PD patients’ induced-pluripotent stem cells (iPSCs), we examined TFEB activity and regulation of the ALP in dopaminergic neuronal cultures generated from iPSC lines harboring heterozygous GBA1 mutations and the CRISPR/Cas9-corrected isogenic controls. Our data showed a significant decrease in TFEB transcriptional activity and attenuated expression of many genes in the CLEAR network in GBA1 mutant neurons, but not in the isogenic gene-corrected cells. …”

Supplementary Material for: Characteristics of asthmatic patients with IL18R1 differential expression in induced sputum by figshare admin karger (2628495)

“…IL18R1high asthma had higher FeNO levels, higher peripheral blood eosinophil counts, lower FEV1/FVC%, and higher Th2 cytokine (IL-4, IL-5, and IL-13) expression than IL18R1low subgroup or controls. IL18R1high asthma had a significant decrease in FeNO and more improvement in FEV1 during inhaled corticosteroid (ICS) treatment compared with patients having the IL18R1low subgroup. …”

Measurements per sample and cycle. by David Nora (10098723)

“…The outcome demonstrates that the variables by which we test the edge efficiency of lithic raw materials are highly relevant for raw material selection and, consequently, may have been of utmost importance in influencing the decision-aking process of past hunter-gatherers. A decrease in tool efficiency during use may have constrained daily activities, necessitating technological adaptations. …”

Detailed view of the SMARTTESTER® device. by David Nora (10098723)

“…The outcome demonstrates that the variables by which we test the edge efficiency of lithic raw materials are highly relevant for raw material selection and, consequently, may have been of utmost importance in influencing the decision-aking process of past hunter-gatherers. A decrease in tool efficiency during use may have constrained daily activities, necessitating technological adaptations. …”

Data Sheet 1_Dynamics and drivers of the carbonate system: response to terrestrial runoff and upwelling along the Northeastern Colombian Caribbean coast.pdf by Constanza Ricaurte-Villota (14169471)

“…The observed trends in pH and pCO₂ were driven by a decrease in DIC and TA, attributed to increased river runoff, contrasting with typical ocean acidification trends driven by rising atmospheric CO₂ levels.…”

Data Sheet 1_Global, regional and national burden of neck pain in children and adolescents: GBD 2021 systematic analysis.pdf by Chao Sun (139686)

“…Background<p>Neck pain (NP) has emerged as a significant health concern among children and adolescents, with potential lifelong consequences. …”

Image 1_Screening of LAB strains and their co-culture fermentation with Bacillus subtilis of Cili fruit substrate: impact on γ-aminobutyric acid enrichment, key enzyme activities,... by Angelo Uriho (20992232)

“…Compared to B. subtilis fermented substrate (Bs), a significant decrease in pH (4.89, except BsLf), increase in TTA (19.30–29.20 mL) was observed after co-culture fermentation of Cili fruit. …”

CONSORT flow chart of included patients. by Zhiwei Li (131853)

“…Furthermore, PCV-VG was associated with an increased center of ventilation (45.1 ± 3.7 vs. 41.7 ± 3.5, P < 0.05), a decrease in global inhomogeneity (GI) (0.85 ± 0.16 vs. 1.06 ± 0.30, P < 0.05), and a reduction in regional ventilation delay index (RVDI) (10.5 ± 4.5 vs. 15.9 ± 5.3, P < 0.05), when compared to VCV. …”

Table 1_Screening of LAB strains and their co-culture fermentation with Bacillus subtilis of Cili fruit substrate: impact on γ-aminobutyric acid enrichment, key enzyme activities,... by Angelo Uriho (20992232)

“…Compared to B. subtilis fermented substrate (Bs), a significant decrease in pH (4.89, except BsLf), increase in TTA (19.30–29.20 mL) was observed after co-culture fermentation of Cili fruit. …”

Imaging equipment, acquisition settings. by David Nora (10098723)

“…The outcome demonstrates that the variables by which we test the edge efficiency of lithic raw materials are highly relevant for raw material selection and, consequently, may have been of utmost importance in influencing the decision-aking process of past hunter-gatherers. A decrease in tool efficiency during use may have constrained daily activities, necessitating technological adaptations. …”

Ventilation parameters. by Zhiwei Li (131853)

“…Furthermore, PCV-VG was associated with an increased center of ventilation (45.1 ± 3.7 vs. 41.7 ± 3.5, P < 0.05), a decrease in global inhomogeneity (GI) (0.85 ± 0.16 vs. 1.06 ± 0.30, P < 0.05), and a reduction in regional ventilation delay index (RVDI) (10.5 ± 4.5 vs. 15.9 ± 5.3, P < 0.05), when compared to VCV. …”

Experience-dependent and temporally restricted serotonin signaling and synaptic glomeruli pruning. by Vanessa Kay Miller (19775496)

“…Two-way ANOVA with Tukey’s multiple comparison shows a highly significant decrease in the Or42a OSN innervation (<i>n</i> = 28/condition, <i>p</i> = 7.45 × 10⁻¹¹) and increase in serotonin (<i>n</i> = 28/condition, <i>p</i> = 4.10 × 10⁻¹⁴). …”

Image 1_Behavioral benefits of GSK-3β inhibition and state-dependent microtubule signatures in the Fmr1-KO mouse.jpeg by John Kealy (17399515)

“…SB216763 normalized social discrimination in 3-CST, while AF3581 only produced a non-significant positive trend. Neither compound altered α-tubulin PTMs. …”

Data Sheet 1_Decoding MexB efflux pump genes: structural, molecular, and phylogenetic analysis of multidrug-resistant and extensively drug-resistant Pseudomonas aeruginosa.docx by Muhammad Bilal Habib (20589857)

“…Following addition of efflux pump inhibitor carbonyl cyanide m-chlorophenyl hydrazone (CCCP), a significant decrease (p<0.05) in MIC was observed in resistance, that revealed the presence of active efflux pump system. …”

<b>Three-year follow-up after antiviral treatment in new-onset type 1 diabetes. Results from the Diabetes Virus Detection and Intervention trial.</b> by Ida M. Mynarek (20479470)

“…<p dir="ltr"><b>Objective</b></p><p dir="ltr">In the Diabetes Virus Detection and Intervention trial, antiviral treatment with pleconaril and ribavirin was shown to decrease the decline in endogenous C-peptide one year after diagnosis of type 1 diabetes in children and adolescents compared to placebo. …”

Opposing mechanisms by which miRNAs mediate distinct Nrf1 and Nrf2 regulation of epithelial–mesenchymal transition in hepatocellular carcinoma by Juan Chen (61123)

“…The <i>Nrf1α</i>^{<i>–/–</i>}-leading EMT results from a significant decrease in the epithelial CDH1 expression, plus another increased expression of the mesenchymal CDH2. …”

The context for each survey round. by Robert C. Hughes (2726941)

“…In conclusion, despite adaptations over time and the decrease in reported disruptions, prolonged economic shock was associated with multiple adverse effects on Nurturing Care. …”

Table 1_High-dose medium-term HMB supplementation did not trigger body composition changes in trained and untrained males under usual conditions or high-intensity functional exerci... by Krzysztof Durkalec-Michalski (4691311)

“…Nevertheless, there was an impact (p < 0.05) from training status (but not HMB/PLA) on FM (kg; slight increases in UTR) and TBW (slight decreases in UTR).</p>Discussion<p>The individually adjusted high HMB dose did not change body mass and composition in trained or untrained individuals during a three-week exclusive supplementation or three-week supplementation in combination with additional HIFT stimuli. …”

Survey respondent characteristics by round. by Robert C. Hughes (2726941)

“…In conclusion, despite adaptations over time and the decrease in reported disruptions, prolonged economic shock was associated with multiple adverse effects on Nurturing Care. …”

Key results by category and survey round. by Robert C. Hughes (2726941)

“…In conclusion, despite adaptations over time and the decrease in reported disruptions, prolonged economic shock was associated with multiple adverse effects on Nurturing Care. …”